Treatment outcomes and factors associated with “successful treatment” among tuberculosis patients at peripheral health settings of Northern Ethiopia: a registry-based retrospective case-series analysis.

Abstract Objective Evidence on treatment outcomes and identifying factors facilitating treatment success through a register based retrospective study have significant contribution in the improvement of a National Tuberculosis Program. However there is a scarcity of data from peripheral health settings in Ethiopia. Therefore this study was aimed at determining treatment outcomes and factors associated with “successful treatment” outcomes among tuberculosis patients.Results A total of 3445 patient records were included. More than half, (58%) were males and the mean age was 33.88 ± 16.91 (range: 0-90). Majority, 1471 (42.7%) had extra-pulmonary TB. From the total TB patients, 18.8% were HIV co infected. The overall treatment success rate was 89.5%. The treatment outcome of TB patients were 371 (10.8%) cured, 2234 (64.8) treatment completed, died 119 (3.5%) died, 9 (0.3%) failed, 178 (5.1%) defaulted and 534 (15.5%) were transferred out. A successful treatment outcome was achieved in 2605 (89.3%). Multinomial regression analysis revealed that being new treatment case (AOR 1.76; 95% CI: 1.19 to 2.60, p=0.005) and age less than 17 years old (AOR 1.65; 95% CI: 1.01 to 2.68, p=0.045) to be statistically associated with favorable treatment outcome.