Evaluation of the Effects of Tetrapleura tetraptera Extract and Clomiphene Citrate to Determine Influence of Reproductive Hormones and Estrous Cycle on Leukocyte Counts: Novel Evidence for a Potential Developmental Link Between Luteinizing Hormone and MID Cells

\n\tEstrous cycle influences circulating leukocyte count via reproductive hormones. Tetrapleura tetraptera extract has been shown to cause an increase in leukocyte count. Our previous work showed thatTetrapleura tetraptera pod extract inhibited LH and estrogen around ovulation stage. Therefore, the present study evaluated the effects of Tetrapleura tetraptera extracts and clomiphene citrate on leukocyte counts in order to determine whether the varying reproductive hormones secreted in both extracts and drug, and estrous cycle caused alteration in leukocyte counts.