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Review of: "Effect of neutrophil-to-lymphocyte ratio and vitamin D3 levels on the pathological complete response after neoadjuvant treatment in TNBC and HER2-positive early breast cancer – results of a prospective study"

Rapport d'évaluation 2023 Anglais

Résumé

Thank you for the opportunity to review your manuscript which is entitled, "Effect of neutrophil-to-lymphocyte ratio and vitamin D3 levels on the pathological complete response after neoadjuvant treatment in TNBC and HER2-positive early breast cancer -results of a prospective study" (Qeios ID: HTU980).Authors evaluated the possibility of using neutrophil-to-lymphocyte ratio as useful tool for predicting neoadjuvant treatment outcome in triple negative and HER-2 early state breast cancer patients.The concept is very interesting and the article is well written with much competence.The methods adopted are very appropriate, and the results are properly described and discussed logically.The article is well organized with a good flow and ended with an apt conclusion.I recommend publication of the paper after effecting some minor corrections.My comments for the authors are below: Authors evaluated the possibility of using neutrophil-to-lymphocyte ratio as useful tool for predicting neoadjuvant treatment outcome in triple negative and HER-2 early state breast cancer patients.The concept is very interesting and the article is properly organized and well written with clarity.However, I have suggested the following minor corrections: Abstract 1.There may be need to include findings on vitamin D3 in result and conclusion statements in the abstract with regards to the title of the study.

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Aprioku, J. S. (2023). Review of: "Effect of neutrophil-to-lymphocyte ratio and vitamin D3 levels on the pathological complete response after neoadjuvant treatment in TNBC and HER2-positive early breast cancer – results of a prospective study". https://doi.org/10.32388/htu980

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