659 publication(s) trouvée(s)
Article scientifique
Detection of horizontal sequence transfer in microorganisms in the genomic era
Abstract Sequence transfer and genome remodeling are very frequent events in microorganisms, especially prokaryotes. This is due to the mosaic …
Article scientifique
Incidence, antifungal resistance properties, and virulence traits of candida species isolated from HIV/AIDS Patients from the hospital system in Kenya
ABSTRACT Candidiasis is the most common fungal infection in hospitalized patients with acquired immune deficiency syndrome resulting to morbidity and …
Article scientifique
Protective human IgE responses are promoted by comparable life-cycle dependent Tegument Allergen-Like protein expression in Schistosoma haematobium and Schistosoma mansoni infection
Abstract Schistosoma haematobium is the most prevalent of the human-infecting schistosome species, causing significant morbidity in endemically exposed populations. Despite …
Article scientifique
First fully-automated AI/ML virtual screening cascade implemented at a drug discovery centre in Africa
Abstract We present ZairaChem, an artificial intelligence (AI)- and machine learning (ML)-based tool to train small-molecule activity prediction models. ZairaChem …
Article scientifique
Common predators and factors influencing their abundance in Anopheles funestus aquatic habitats in rural south-eastern Tanzania
Abstract Background The role that larval predators play in regulating the population of malaria vectors remains relatively unknown. This study …
Article scientifique
Plasmodium falciparum adapts its investment into replication versus transmission according to the host environment
Abstract The malaria parasite life cycle includes asexual replication in human blood, with a proportion of parasites differentiating to gametocytes …
Article scientifique
Simple Models For Neuroscience Research Discoveries: How Often Are These Models Used In Africa
ABSTRACT Simple animal model systems such as Drosophila , Zebrafish, and C. Elegans have enabled numerous breakthroughs in understanding human …
Article scientifique
Intervention reducing malaria parasite load in vector mosquitoes: no impact on Plasmodium falciparum extrinsic incubation period and the survival of Anopheles gambiae
Abstract In the fight against malaria, transmission blocking interventions (TBIs) are promising approaches to complement conventional tools. They aim to …
Article scientifique
The Megachilidae (Hymenoptera, Apoidea, Apiformes) of the Democratic Republic of Congo curated at the Royal Museum for Central Africa (RMCA, Belgium)
Abstract Natural history collections (NHCs) are a cornerstone of entomology, and the conservation of specimens is the essential prerequisite for …
Article scientifique
A Very virulent infectious bursal disease virus closely related to New York strain isolated from vaccinated small-scale broiler poultry farm in Addis Ababa, Ethiopia
Abstract Infectious bursal disease virus (IBDV) was initially identified in the USA. The first IBD case in Ethiopia was reported …
Article scientifique
Widely targeted metabolomics analysis reveals differences in volatile metabolites among four Angelica species
Abstract Angelica L. has attracted global interest for its traditional medicinal uses and commercial values. However, few studies have focused …
Article scientifique
Investigation on the Effectiveness of Lactobacillus plantarum in Enhancing the Folate content of Injera made with Different Cereals
ABSTRACT Injera is an Ethiopian fermented pancake-like flatbread made from different cereals. The aim of the study was to investigate …
Article scientifique
Quantification of the diversity sampling bias resulting from rice root bacterial isolation on popular and nitrogen-free culture media, using 16S amplicon barcoding
Abstract Culturing bacteria from plant material is well known to introduce a strong bias compared to the real diversity present …
Article scientifique
Physico-chemical and microbiological characteristics of honey produced by stingless bees (Meliponula beccarii) from the Oromia Region, Ethiopia
Abstract The study was designed to characterize the Physico-chemical and microbiological properties of stingless bee honey (Meliponula beccarii L.) in …
Article scientifique
Production of Rabies virus-specific monoclonal antibodies and evaluation of their neutralizing potential
Abstract Rabies is a severe viral infection that causes acute encephalomyelitis, with a case fatality rate of nearly 100% following …
Article scientifique
Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria mosquito
Abstract Species distributed across heterogeneous environments often evolve locally adapted ecotypes, but understanding of the genetic mechanisms involved in their …
Article scientifique
Preparation of inactivated whole culture vaccine composed of Pasteurella multocida, Avibacterium paragallinarum , and Ornithobacterium rhinotracheale and evaluation of its protective efficacy in chickens
Abstract Poultry, mainly chickens and its white meat represents one of the main, nutritionally valuable, and affordable red meat replacer …
Article scientifique
Genome editing of an African elite rice variety confers resistance against endemic and emerging Xanthomonas oryzae pv. oryzae strains
Abstract Bacterial leaf blight (BB) of rice, caused by Xanthomonas oryzae pv. oryzae ( Xoo ), threatens global food security …
Article scientifique
Nasopharyngeal competition dynamics are likely to be altered following vaccine introduction: bacteriocin prevalence and diversity among Icelandic and Kenyan pneumococci
Abstract Bacteriocins are antimicrobial peptides produced by bacteria to inhibit other bacteria in the surrounding environment. Streptococcus pneumoniae is a …
Article scientifique
GHB degradation via TCA cycle is the major metabolic route in Arabidopsis thaliana
Abstract Gamma-hydroxybutyric acid (GHB) is a reduced product of the chemically reactive succinic semi-aldehyde (SSA), which itself is produced from …