659 publication(s) trouvée(s)
Article scientifique
RNA-Seq-Pop: Exploiting the sequence in RNA-Seq - a Snakemake workflow reveals patterns of insecticide resistance in the malaria vector Anopheles gambiae
Abstract Background We provide a reproducible and scalable Snakemake workflow, called RNA-Seq-Pop, which provides end-to- end analysis of RNA-Seq data …
Article scientifique
Profiling RNA at chromatin targets in situ by antibody-targeted tagmentation
Abstract Whereas techniques to map chromatin-bound proteins are well-developed, mapping chromatin-associated RNAs remains a challenge. Here we describe Reverse Transcribe …
Article scientifique
Blue turns to grey - Palaeogenomic insights into the evolutionary history and extinction of the blue antelope ( Hippotragus leucophaeus )
Abstract The blue antelope ( Hippotragus leucophaeus ) is the only large African mammal species to have become extinct in …
Article scientifique
Phylogenetic analysis of the origin and spread of plague in Madagascar
Abstract Background Plague is a zoonotic disease caused by the bacterium Yersinia pestis , highly prevalent in the Central Highlands, …
Article scientifique
Impact of dominance rank specification in dyadic interaction models
Abstract Dominance rank is a vital descriptor of social dynamics in animal societies and regularly used in studies to explain …
Article scientifique
High resolution species assignment of Anopheles mosquitoes using k -mer distances on targeted sequences
Abstract The ANOSPP amplicon panel is a genus-wide targeted sequencing panel to facilitate large-scale monitoring of Anopheles species diversity. Combining …
Article scientifique
Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection
Abstract Background Undernutrition and schistosomiasis are public health problems and often occur in low and middle-income countries. Protein undernutrition can …
Article scientifique
How drought affects range and variability of environmental conditions in subtropical South African estuaries
Abstract Globally estuaries are under increasing pressure from human development impacts as well as the growing effects of climate change …
Article scientifique
High-throughput profiling of natural acquired humoral immune response to a large panel of known and novel full length ectodomain P. falciparum merozoite vaccine candidates under reduced malaria transmission
ABSTRACT Despite recent progress in the fight against malaria, it still remains a global health challenge necessitating development of intervention …
Article scientifique
Integrated pretraining with evolutionary information to improve RNA secondary structure prediction
A bstract RNA secondary structure prediction is a fundamental task in computational and molecular biology. While machine learning approaches in …
Article scientifique
Genomic surveillance of Bacillus cereus sensu lato strains isolated from meat and poultry products in South Africa enables inter- and intra-national surveillance and source tracking
Abstract Members of the Bacillus cereus sensu lato ( s.l. ) species complex, also known as the B. cereus group, …
Article scientifique
The Antimicrobial Activity of Pechuel-Loeschea leubnitziae Leaf Extract and its Effect on The Expression Level of Methicillin Resistant Staphylococcus Aureus and Candida albicans Virulence-Associated Genes
ABSTRACT The complete halt in the synthesis of new effective antimicrobial compounds is a global concern. Pathogenic microorganisms’ virulence mechanisms …
Article scientifique
Genome-wide analysis of Schistosoma mansoni reveals population structure and praziquantel drug selection pressure within Ugandan hot-spot communities
Abstract Populations within schistosomiasis control areas, especially those in Africa, are recommended to receive regular mass drug administration (MDA) with …
Article scientifique
Impact of contamination on biology, biochemical, and histology of Eobania vermiculata and Monacha obstructa during different seasons in Ismailia, Egypt
Abstract Land snails are found to be an appropriate sentinel organism, and the biomarkers chosen are effective for terrestrial heavy …
Article scientifique
Seroprevalence of brucellosis and molecular characterization of Brucella spp. from slaughtered cattle in Rwanda
Abstract Bovine brucellosis is endemic in Rwanda, although, there is paucity of documented evidence about the disease in slaughtered cattle. …
Article scientifique
Influence of selected plant growth stimulators in enhancing germinability and germination parameters of Zea mays L. under microgravity conditions simulated by a two-dimensional clinostat
Abstract The earth has become increasingly overcrowded as a result of rapid urbanization and population growth, predicting that its carrying …
Article scientifique
The natural compound TMYX reduces SAN cells rate by antagonizing the cAMP modulation of f-channels
Abstract Tongmai Yangxin (TMYX), is a complex compound of a Traditional Chinese Medicine (TCM) used to treat several cardiac rhythm …
Article scientifique
Validation of cervical lesion proportion measure using a gridded imaging technique to assess cervical pathology in women with genital schistosomiasis
Abstract Female genital schistosomiasis (FGS) is characterized by a pattern of lesions which manifest at the cervix and the vagina, …
Article scientifique
Low-coverage reduced representation sequencing reveals subtle within-island genetic structure in Aldabra giant tortoises
Abstract Aldabrachelys gigantea (Aldabra giant tortoise) is one of only two giant tortoise species left in the world and survives …
Article scientifique
Genomic variation across a clinical Cryptococcus population linked to disease outcome
Abstract Cryptococcus neoformans is the causative agent of cryptococcosis, a disease with poor patient outcomes, accounting for approximately 180,000 deaths …