391 publication(s) trouvée(s)
Article scientifique
Oxindole–benzothiazole hybrids as CDK2 inhibitors and anticancer agents: design, synthesis and biological evaluation
Abstract In the current study, molecular hybridization between the oxindole core and benzothiazole system through an acetohydrazide moiety was accomplished …
Article scientifique
A sustainable HPLC method coupled with diode array detection for versatile quantification of telmisartan, chlorthalidone and amlodipine in a fixed-dose antihypertensive formulation and dissolution studies
Abstract Cardiovascular diseases, especially hypertension, stand as prominent contributors to global mortality. Hypertension, often referred to as a silent killer …
Article scientifique
Laser enhanced photothermal effect of silver nanoparticles synthesized by chemical and green method on Gram-positive and Gram-negative bacteria
PURPOSE: The antibacterial properties of silver nanoparticles (AgNPs) are extensively identified. In large quantities, they might be harmful. So many …
Article scientifique
Novel thiazole-based cyanoacrylamide derivatives: DNA cleavage, DNA/BSA binding properties and their anticancer behaviour against colon and breast cancer cells
Abstract A novel series of 2-cyano-3-(pyrazol-4-yl)- N -(thiazol-2-yl)acrylamide derivatives ( 3a – f ) were synthesized using Knoevenagel condensation and …
Article scientifique
Synthesis of new binary trimethoxyphenylfuran pyrimidinones as proficient and sustainable corrosion inhibitors for carbon steel in acidic medium: experimental, surface morphology analysis, and theoretical studies
Abstract In this study, synthesis and assessment of the corrosion inhibition of four new binary heterocyclic pyrimidinones on CS in …
Article scientifique
Full green assay of parenteral dosage forms of polymyxins utilizing xanthene dye: application to content uniformity testing
Abstract Due to the lack of other treatment options, a rebirth of polymyxins is urgently required. Colistin (also called polymyxin …
Article scientifique
Independent concentration extraction as a novel green approach resolving overlapped UV–Vis binary spectra and HPTLC-densitometric methods for concurrent determination of levocloperastine and chlorpheniramine
Abstract Background The proposed research study introduces independent concentration extraction (ICE) as a novel UV–Vis spectrophotometric approach. The approach can …
Article scientifique
Eco-conscious potentiometric sensing: a multiwalled carbon nanotube-based platform for tulathromycin monitoring in livestock products
Abstract Tulathromycin (TUL) is a widely used veterinary antibiotic for treating bovine and porcine respiratory infections. Consuming animal-derived food contaminated …
Article scientifique
Chromatographic fingerprinting of ipratropium and fenoterol in their novel co-formulated inhaler treating major respiratory disorders; application to delivered dose uniformity testing along with greenness and whiteness assessment
Abstract Ipratropium bromide (IPR) and fenoterol hydrobromide (FEN) have recently been combined in a promising inhaler to treat two prevalent …
Article scientifique
Sorption of chromium from aqueous solutions using Fucus vesiculosus algae biosorbent
The presence of heavy metals in wastewater is an environmental concern and the current treatment procedures are very expensive so …
Article scientifique
Promising superabsorbent hydrogel based on carboxymethyl cellulose and polyacrylic acid: synthesis, characterization, and applications in fertilizer engineering
The combination of hydrogel and fertilizer as slow release fertilizer hydrogel (SRFH) has become one of the most promising materials …
Article scientifique
Green synthesis of Carbonized Chitosan-Fe3O4-SiO2 nano-composite for adsorption of heavy metals from aqueous solutions
Abstract Water pollution with heavy metals owing to industrial and agricultural activities have become a critical dilemma to humans, plants …
Article scientifique
Metal complexes featuring a quinazoline schiff base ligand and glycine: synthesis, characterization, DFT and molecular docking analyses revealing their potent antibacterial, anti-helicobacter pylori, and Anti-COVID-19 activities
Abstract Mixed ligand complexes of manganese(II), cobalt(II), copper(II), and cadmium(II)with an innovative Schiff base ligand denoted as (L1), 4-(2-((1E,2E)-1-(2-(p-tolyl)hydrazineylidene)propan-2-ylidene)hydrazineyl), served …
Article scientifique
Green micellar UPLC and complementary eco-friendly spectroscopic techniques for simultaneous analysis of anti-COVID drugs: a comprehensive evaluation of greenness, blueness, and whiteness
Abstract The development of sustainable analytical methodologies that minimize hazards, waste generation, and energy consumption has become crucial. This study …
Article scientifique
Bimetallic MOF-based electrochemical sensor for determination of paracetamol in spiked human plasma
Abstract Metal-organic frameworks (MOFs) with their exceptional properties have the potential to revolutionize the field of electrochemistry and pave the …
Article scientifique
Drug repurposing of pyrazolotriazine derivatives as potential anti-SARS-CoV-2 agents: in vitro and in silico studies
Abstract The search for new molecules targeting SARS-CoV-2 has been a priority since 2020. The continuous evolution of new mutants …
Article scientifique
Implementation of green-assessed nanotechnology and quality by design approach for development of optical sensor for determination of tobramycin in ophthalmic formulations and spiked human plasma
A fast eco-friendly colorimetric method was developed for the determination of Tobramycin in drug substance, ophthalmic formulations, and spiked human …
Article scientifique
Synthesis, docking and characterization of some novel 5-(S-alkyl)-1.3.4-thiadiazole-2-carboxamide derivatives as anti-inflammatory and antibacterial agents
Abstract Because of the great pharmacological and industrial significance of 1,3,4-thiadiazole and its related compounds, researchers are still very interested …
Article scientifique
Facile synthesis of copper nitroprusside chitosan nanocomposite and its catalytic reduction of environmentally hazardous azodyes
Abstract One of the biggest issues affecting the entire world currently is water contamination caused by textile industries’ incapacity to …
Article scientifique
Development and validation of a precise flow injection method for the assessment of brexpiprazole, with application to pharmaceutical dosage forms and human plasma analysis
Abstract A novel antipsychotic medication named brexpiprazole (BRX) is currently employed for the treatment of schizophrenia and other psychotic disorders. …