269 publication(s) trouvée(s)
Article scientifique
A cross-sectional survey on the use of herbal tea among Cameroonian adults (18–65 years)
BACKGROUND: In respect of the WHO's commendation to incorporate traditional medicine (TM) in health care, the Cameroon government wants to …
Article scientifique
Evaluation of anti-quorum sensing and antibiofilm effects of secondary metabolites from Gambeya lacourtiana (De Wild) Aubr. & Pellegr against selected pathogens
BACKGROUND: Microbial infections cause serious health problems especially with the rising antibiotic resistance which accounts for about 700,000 human deaths …
Article scientifique
Jatrophone: a cytotoxic macrocylic diterpene targeting PI3K/AKT/NF-κB pathway, inducing apoptosis and autophagy in resistant breast cancer cells
Abstract Background Breast cancer is a prevalent malignant tumor that affects women worldwide. The primary challenge in treating breast cancer …
Article scientifique
Enhanced anti-inflammatory and ulcerogenicity of Ibuprofen microsphere formulations using Irvingia wombolu fat (IRW) and moringa oil (MO) as co-lipids
Ibuprofen is a member of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAIDs) with anti-inflammatory, analgesic, and antipyretic activities …
Article scientifique
In-silico and in-vitro assessments of some fabaceae, rhamnaceae, apocynaceae, and anacardiaceae species against Mycobacterium tuberculosis H37Rv and triple-negative breast cancer cells
Abstract Medicinal plants play a huge role in the treatment of various diseases in the Limpopo province (South Africa). Traditionally, …
Article scientifique
Metabolic bioprofiling of different Glycyrrhiza glabra solvent fractions for the identification of anti-adenoviral compounds using LC-HRMS/MS and in-vitro cytopathic assay coupled with chemometry
Abstract Human adenovirus type-7 (HAdV-7) is a common pathogen that may cause significant morbidity as well as severe complications. Currently, …
Article scientifique
Repurposing drugs to treat trichinellosis: in vitro analysis of the anthelmintic activity of nifedipine and Chrysanthemum coronarium extract
Abstract Albendazole is the most common benzimidazole derivative used for trichinellosis treatment but has many drawbacks. The quest for alternative …
Article scientifique
Comparative anticancer effects of Annona muricata Linn (Annonaceae) leaves and fruits on DMBA-induced breast cancer in female rats
BACKGROUND: Numerous studies have reported the anti-cancer effects of different parts of Annona muricata Linn, however ; most of them …
Article scientifique
Anticancer potential of Carica papaya Linn black seed extract against human colon cancer cell line: in vitro study
BACKGROUND: Since cancer is one of the most prevalent diseases in the world, further studies are needed to identify the …
Article scientifique
Anti-cancer effect of nano-encapsulated boswellic acids, curcumin and naringenin against HepG-2 cell line
BACKGROUND: liver cancer is one of the most common cancers in the world. So far, there is no gold standard …
Article scientifique
Gallic acid and metformin co-administration reduce oxidative stress, apoptosis and inflammation via Fas/caspase-3 and NF-κB signaling pathways in thioacetamide-induced acute hepatic encephalopathy in rats
BACKGROUND: Hepatic encephalopathy (HE) is a consequence of chronic or acute liver diseases. This study evaluates the combined effect of …
Article scientifique
Myco-synthesized copper oxide nanoparticles using harnessing metabolites of endophytic fungal strain Aspergillus terreus: an insight into antibacterial, anti-Candida, biocompatibility, anticancer, and antioxidant activities
Abstract Background The overuse of antibiotics leads to the emergence of antibiotic-resistant microbes which causes high mortality worldwide. Therefore, the …
Article scientifique
Unani Tibb practitioners’ perceptions and attitudes towards spirituality and spiritual care in Unani Tibb practice in South Africa
BACKGROUND: Unani Tibb is an Arabic term which means Greek medicine. It is an ancient holistic medical system based on …
Article scientifique
Antimicrobial, antioxidant activities, and total phenolic contents of Pycnanthus angolensis Sap and Cryptolepis sanguinolenta root extracts
The death of many people in tropical countries can be attributed to microbial infection, probably, because synthetic antibiotics are failing …
Article scientifique
Phytopharmaceutical practices of traditional health practitioners in Burkina Faso: a cross-sectional study
BACKGROUND: Traditional health practitioners constitute an important part of the health care system in Burkina Faso, particularly in the supply …
Article scientifique
Antioxidant evaluation and computational prediction of prospective drug-like compounds from polyphenolic-rich extract of Hibiscus cannabinus L. seed as antidiabetic and neuroprotective targets: assessment through in vitro and in silico studies
Abstract Background Reports have implicated diabetes mellitus (DM) and Alzheimer’s disease (AD) as some of the global persistent health challenges …
Article scientifique
In vitro antiplasmodial activity and toxicological profile of extracts, fractions and chemical constituents of leaves and stem bark from Dacryodes edulis (Burseraceae)
Abstract Background Dacryodes edulis is a plant that belongs to the Burseraceae family. It is widely used traditionally alone or …
Article scientifique
Cytotoxic flavone-C-glycosides from the leaves of Dypsis pembana (H.E.Moore) Beentje & J.Dransf., Arecaceae: in vitro and molecular docking studies
BACKGROUND: Cancer poses a health threat, with an increased incidence worldwide. Thus, it is essential to develop new natural anticancer …
Article scientifique
Safety profile of colocasia esculenta tuber extracts in benign prostate hyperplasia
INTRODUCTION: This study was motivated by the increasing global incidence of benign prostatic hyperplasia (BPH) and the promising potential of …
Article scientifique
Antimicrobial, antioxidant, and sun protection potential of the isolated compounds from Spermacoce princeae (K. Schum)
Abstract Background Spermacoce princeae (K. Schum) has been used in the treatment of bacterial skin infections in Uganda. Pharmacological studies …