1373 publication(s) trouvée(s)
Article scientifique
Implementation of evidence-based multiple focus integrated intensified TB screening to end TB (EXIT-TB) package in East Africa: a qualitative study
INTRODUCTION: Tuberculosis (TB) remains a major cause of morbidity and mortality, especially in sub-Saharan Africa. We qualitatively evaluated the implementation …
Article scientifique
Cost-effectiveness analysis of typhoid conjugate vaccines in an outbreak setting: a modeling study
BACKGROUND: Several prolonged typhoid fever epidemics have been reported since 2010 throughout eastern and southern Africa, including Malawi, caused by …
Article scientifique
Modelling the impact of combining HIV prevention interventions on HIV dynamics in fishing communities in Uganda
BACKGROUND: In countries with mature generalized HIV epidemics such as Uganda, there are still groups of individuals that are disproportionately …
Article scientifique
Case-control study of human anthrax outbreak investigation in farta woreda, South Gondar, Northwest Ethiopia
BACKGROUND: Anthrax is a zoonotic disease caused by the Bacillus anthracis bacteria, which is one of the top five important …
Article scientifique
Fluoroquinolone resistance among fecal extended spectrum βeta lactamases positive Enterobacterales isolates from children in Dar es Salaam, Tanzania
BACKGROUND: Fluoroquinolones have been, and continue to be, routinely used for treatment of many bacterial infections. In recent years, most …
Article scientifique
Prevalence and factors associated with reported adverse-events among patients on multi-drug-resistant tuberculosis treatment in two referral hospitals in Uganda
BACKGROUND: Multi-drug-resistant tuberculosis (MDR-TB) treatment involves toxic drugs that cause adverse events (AEs), which are life-threatening and may lead to …
Article scientifique
Seroprevalence of hepatitis B virus surface antigen (HBsAg) in Egypt (2000–2022): a systematic review with meta-analysis
BACKGROUND: Hepatitis B infection seriously threatens global public health, especially in developing nations. Despite several investigations on HBV incidence, the …
Article scientifique
HIV-1 Tat amino acid residues that influence Tat-TAR binding affinity: a scoping review
HIV-1 remains a global health concern and to date, nearly 38 million people are living with HIV. The complexity of …
Article scientifique
Spatiotemporal overlapping of dengue, chikungunya, and malaria infections in children in Kenya
Malaria, chikungunya virus (CHIKV), and dengue virus (DENV) are endemic causes of fever among children in Kenya. The risks of …
Article scientifique
Evaluation of the impact of COVID-19 in people coinfected with HIV and/or tuberculosis in low-income countries: study protocol for mixed methods research in Burkina Faso
BACKGROUND: An issue of particular concern is the impact of the 2019 novel coronavirus (2019 nCOV) on the people coinfected …
Article scientifique
Applying mathematical modelling to estimate the impact of COVID-19-related VMMC service disruptions on new HIV infections in Zimbabwe
BACKGROUND: The COVID-19 pandemic has overwhelmed health systems with knock on effects on diagnosis, treatment, and care. To mitigate the …
Article scientifique
Comparison of paediatric infectious disease deaths in public sector health facilities using different data sources in the Western Cape, South Africa (2007–2021)
BACKGROUND: Routinely collected population-wide health data are often used to understand mortality trends including child mortality, as these data are …
Article scientifique
The clinical and epidemiological characteristics of a series of patients living with HIV admitted for COVID-19 in a district hospital
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic continues to evolve. Globally, COVID-19 continues to strain even the most resilient healthcare …
Article scientifique
Candida bloodstream infection among children hospitalised in three public-sector hospitals in the Metro West region of Cape Town, South Africa
BACKGROUND: Candida bloodstream infection (BSI) causes appreciable mortality in neonates and children. There are few studies describing the epidemiology of …
Article scientifique
Impact of population based indoor residual spraying with and without mass drug administration with dihydroartemisinin-piperaquine on malaria prevalence in a high transmission setting: a quasi-experimental controlled before-and-after trial in northeastern Uganda
BACKGROUND: Declines in malaria burden in Uganda have slowed. Modelling predicts that indoor residual spraying (IRS) and mass drug administration …
Article scientifique
Predictors of the observed high prevalence of loss to follow-up in ART-experienced adult PLHIV: a retrospective longitudinal cohort study in the Tanga Region, Tanzania
BACKGROUND: Antiretroviral therapy (ART) programs have expanded rapidly, and they are now accessible free of charge, yet "loss to follow-up, …
Article scientifique
Reducing urinary catheter use in geriatric patients - results of a single-center champion-led intervention
BACKGROUND: Indwelling urinary tract catheters (UTC) are a well-known risk factor for urinary tract infections (UTI). Because geriatric patients are …
Article scientifique
A comparison of four epidemic waves of COVID-19 in Malawi; an observational cohort study
BACKGROUND: Compared to the abundance of clinical and genomic information available on patients hospitalised with COVID-19 disease from high-income countries, …
Erratum
Correction: Gender differences among patients with drug resistant tuberculosis and HIV co-infection in Uganda: a countrywide retrospective cohort study
Article scientifique
Invasiveness potential of pneumococcal serotypes in children after introduction of PCV13 in Blantyre, Malawi
INTRODUCTION: The introduction of PCV13 to the Malawi infant immunization schedule in 2011 has been associated with reduced disease from …