1373 publication(s) trouvée(s)
Article scientifique
Prevalence of hepatotoxicity among HIV-infected patients in Ethiopia: a systematic review and meta-analysis
Abstract Background Globally, the human immunodeficiency virus has been recognized as a major public health concern. The direct toxicity of …
Article scientifique
Multidrug resistant bacterial infections in severely ill COVID-19 patients admitted in a national referral and teaching hospital, Kenya
BACKGROUND: Bacterial infections are a common complication in patients with seasonal viral respiratory tract infections and are associated with poor …
Article scientifique
Risk factors for severe Covid-19 breakthrough infections: an observational longitudinal study
BACKGROUND: The drive to vaccinate large populations is nowadays the main instrument for combating the pandemic and preventing serious disease …
Article scientifique
Bedaquiline safety, efficacy, utilization and emergence of resistance following treatment of multidrug-resistant tuberculosis patients in South Africa: a retrospective cohort analysis
BACKGROUND: This retrospective cohort study assessed benefits and risks of bedaquiline treatment in multidrug-resistant-tuberculosis (MDR-TB) combination therapy by evaluating safety, …
Article scientifique
‘If I am playing football, I forget that I have this virus’: the challenges and coping strategies of adolescents with perinatally acquired HIV in KwaZulu-Natal, South Africa
BACKGROUND: Adolescents who have acquired HIV perinatally (ALHIV) face unique challenges in taking lifelong antiretroviral therapy (ART), but little is …
Article scientifique
Detection of Salmonella Typhi nucleic acid by RT-PCR and anti-HlyE, -CdtB, -PilL, and -Vi IgM by ELISA at sites in Ghana, Madagascar and Ethiopia
BACKGROUND: We aimed to assess the prevalence of Salmonella Typhi through DNA and IgM-antibody detection methods as a prelude to …
Article scientifique
Effect of Schistosoma haematobium infection on the cognitive functions of preschool age children and benefits of treatment from an endemic area in Zimbabwe
BACKGROUND: Schistosomiasis is known to affect the cognitive functions of children, however, but there is paucity of information on its …
Article scientifique
Serological evidence of chronic pulmonary Aspergillosis in tuberculosis patients in Kenya
BACKGROUND: Pulmonary tuberculosis (PTB) is a significant risk factor for fungal infection. The cavitary lesions post PTB serves as a …
Article scientifique
Clinical malaria incidence and health seeking pattern in geographically heterogeneous landscape of western Kenya
Abstract Background Malaria remains a public health problem in Kenya despite sustained interventions deployed by the government. One of the …
Article scientifique
Escalating pyrethroid resistance in two major malaria vectors Anopheles funestus and Anopheles gambiae (s.l.) in Atatam, Southern Ghana
Abstract Background Aggravation of insecticide resistance in malaria vectors is threatening the efforts to control malaria by reducing the efficacy …
Article scientifique
Development and validation of a risk prediction model for lost to follow-up among adults on active antiretroviral therapy in Ethiopia: a retrospective follow-up study
BACKGROUND: Over 420,000 people have initiated life-saving antiretroviral therapy (ART) in Ethiopia; however, lost-to-follow-up (LTFU) rates continues to be high. …
Article scientifique
Depression management and antiretroviral treatment outcome among people living with HIV in Northwest and East regions of Cameroon
BACKGROUND: Several interventions have shown benefits in improving mental health problems such as depression which is common in people living …
Article scientifique
Low prevalence of hepatitis B virus infection in HIV-uninfected pregnant women in Cape Town, South Africa: implications for oral pre-exposure prophylaxis roll out
BACKGROUND: Oral daily preexposure prophylaxis (PrEP) using emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) is recommended as standard of care for prevention …
Article scientifique
Usability and acceptability of oral fluid hepatitis C self-testing among people who inject drugs in Coastal Kenya: a cross-sectional pilot study
BACKGROUND: People who inject drugs (PWID) are disproportionally affected by hepatitis C virus (HCV) infection and many remain undiagnosed. HCV …
Article scientifique
Modeling the potential impact of pre-exposure prophylaxis for HIV among men who have sex with men in Cameroon
BACKGROUND: Men who have sex with men (MSM) are consistently burdened by HIV at higher levels than other adults. While …
Article scientifique
Facilitators and barriers to COVID-19 vaccination among healthcare workers and the general population in Guinea
INTRODUCTION: The advent of the effective COVID-19 vaccine was the most eagerly expected worldwide. However, this hope quickly became hesitation …
Article scientifique
Relationship between active Helicobacter pylori infection and risk factors of cardiovascular diseases, a cross-sectional hospital-based study in a Sub-Saharan setting
BACKGROUND: Chronic inflammation has been reported as one of the novel coronary heart disease (CHD) risk factors. Knowing that Helicobacter …
Article scientifique
Epidemiological and viral characteristics of undiagnosed HIV infections in Botswana
BACKGROUND: HIV-1 is endemic in Botswana. The country's primary challenge is identifying people living with HIV who are unaware of …
Article scientifique
“I am alive because of her”: factors affecting adherence to combination antiretroviral therapy among people living with HIV in KwaZulu-Natal, South Africa
BACKGROUND: People living with HIV need to take lifelong, combination antiretroviral therapy (cART), but there have been only limited explorations …
Article scientifique
Epidemiology of sexually transmitted infections: trends among patients screened for sexually transmitted infections in rwandan health facilities 2014–2020
BACKGROUND: Sexually Transmitted Infections (STIs) are of great global health concern. Currently, there are limited epidemiological data characterizing STIs in …