1373 publication(s) trouvée(s)
Article scientifique
Molecular epidemiology of Staphylococcus aureus in African children from rural and urban communities with atopic dermatitis
BACKGROUND: Staphylococcus aureus has been associated with the exacerbation and severity of atopic dermatitis (AD). Studies have not investigated the …
Article scientifique
Haematological abnormalities in children with sickle cell disease and non-severe malaria infection in western Kenya
Abstract Background In Plasmodium falciparum infection, clinical conditions such as anaemia, thrombocytopenia and leukocytosis are common. Mutation in haemoglobin sub-unit …
Article scientifique
Effect of hookworm infection and anthelmintic treatment on naturally acquired antibody responses against the GMZ2 malaria vaccine candidate and constituent antigens
BACKGROUND: Malaria and helminths diseases are co-endemic in most parts of sub-Saharan Africa. Immune responses from each of these pathogens …
Article scientifique
Co-infection of HIV in patients with Buruli ulcer disease in Central Ghana
Abstract Background Previous studies have reported that presence and severity of Buruli ulcer (BU) may reflect the underlying immunosuppression in …
Article scientifique
HIV voluntary counseling and testing uptake and associated factors among Ethiopian youths: evidence from the 2016 EDHS using multilevel modeling
BACKGROUND: Existing evidence showed that Human Immunodeficiency Virus counselling and testing uptake among Ethiopian youths is low, and factors contributing …
Article scientifique
Assessing the determinants of Ebola virus disease transmission in Baka Community of the Tropical Rainforest of Cameroon
BACKGROUND: Ebola virus disease (EVD) is a severe, often fatal illness in humans and nonhuman primates caused by the Ebola …
Article scientifique
Prevalence of cryptosporidiosis among children with diarrhoea under five years admitted to Kosti teaching hospital, Kosti City, Sudan
BACKGROUND: Cryptosporidiosis is a disease caused by infection with an intestinal coccidian parasite Cryptosporidium. Cryptosporidium species are the second leading …
Article scientifique
Prevalence of sexually transmitted infections among cervical cancer suspected women at University of Gondar Comprehensive Specialized Hospital, North-west Ethiopia
BACKGROUND: Sexually transmitted infections (STIs) such as Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), and …
Article scientifique
Efficacy and safety of artemisinin-based combination therapies for the treatment of uncomplicated malaria in pediatrics: a systematic review and meta-analysis
Abstract Background Malaria is a major cause of morbidity and mortality in pediatrics in malaria endemic areas. Artemisinin-based combination therapies …
Article scientifique
Improved detection of microbiological pathogens: role of partner and non-governmental organizations
BACKGROUND: Proper detection of disease-causing organisms is very critical in controlling the course of outbreaks and avoiding large-scale epidemics. Nonetheless, …
Article scientifique
Hepatic expression of cholesterol regulating genes favour increased circulating low-density lipoprotein in HIV infected patients with gallstone disease: a preliminary study
BACKGROUND: HIV endemic populations are displaying higher incidence of metabolic disorders. HIV and the standard treatment are both associated with …
Article scientifique
Molecular characterization of high-risk human papillomavirus (HR-HPV) in women in Lomé, Togo
BACKGROUND: The causative agent of cervical cancer referred to as Human papillomavirus (HPV) remains a real public health problem. Many …
Article scientifique
Phenotypic and genotypic drug sensitivity profiles of Mycobacterium tuberculosis infection and associated factors in northeastern Ethiopia
BACKGROUND: Tuberculosis is a devastating and a deadly disease despite the novel advances in its diagnostic tools and drug therapy. …
Article scientifique
Sputum smear grading and associated factors among bacteriologically confirmed pulmonary drug-resistant tuberculosis patients in Ethiopia
Abstract Background The sputum smear bacilliary load is a fundamental indicator of the level of infectiousness in DR-TB patients. However, …
Article scientifique
The utility of point-of-care urinary lipoarabinomannan testing for the diagnosis of tuberculosis in critically ill patients: a prospective observational study
BACKGROUND: Tuberculosis is a major global public health concern. Patients with tuberculosis who require critical care have a high mortality …
Article scientifique
Epidemiological risk factors and the geographical distribution of eight Mycobacterium species
BACKGROUND: Nontuberculous mycobacteria (NTM) are environmental bacterium that may cause and/or compound respiratory diseases in humans. There are over a …
Article scientifique
Risk factors for mortality among patients diagnosed with multi-drug resistant tuberculosis in Uganda- a case-control study
BACKGROUND: The World Health Organization (WHO) End TB strategy aims to reduce mortality due to tuberculosis (TB) to less than …
Article scientifique
Surveillance of the major pathogenic arboviruses of public health concern in Gabon, Central Africa: increased risk of West Nile virus and dengue virus infections
BACKGROUND: Increasing arbovirus infections have been a global burden in recent decades. Many countries have experienced the periodic emergence of …
Article scientifique
Serial interval and incubation period of COVID-19: a systematic review and meta-analysis
Abstract Background Understanding the epidemiological parameters that determine the transmission dynamics of COVID-19 is essential for public health intervention. Globally, …
Article scientifique
Tuberculosis diagnosis cascade in Blantyre, Malawi: a prospective cohort study
BACKGROUND: Tuberculosis (TB) control relies on early diagnosis and treatment. International guidelines recommend systematic TB screening at health facilities, but …