1373 publication(s) trouvée(s)
Article scientifique
Retention of HIV infected pregnant and breastfeeding women on option B+ in Gomba District, Uganda: a retrospective cohort study
BACKGROUND: Lifelong antiretroviral therapy for HIV infected pregnant and lactating women (Option B+) has been rapidly scaled up but there …
Article scientifique
Prevalence and antibiotic susceptibility pattern of CTX-M type extended-spectrum β-lactamases among clinical isolates of gram-negative bacilli in Jimma, Ethiopia
The prevalence of extended-spectrum β-lactamases (ESBLs) have been reported in clinical isolates obtained from various hospitals in Ethiopia. However, there …
Article scientifique
A high burden of asymptomatic genital tract infections undermines the syndromic management approach among adolescents and young adults in South Africa: implications for HIV prevention efforts
BACKGROUND: Youth in southern Africa, particularly adolescent girls and young women, are a key population for HIV prevention interventions. Untreated …
Article scientifique
Methods for conducting a double-blind randomized controlled clinical trial of three days versus five days of amoxicillin dispersible tablets for chest indrawing childhood pneumonia among children two to 59 months of age in Lilongwe, Malawi: a study protocol
BACKGROUND: Pneumonia is the leading infectious cause of death in children under 5 years of age around the globe. In …
Article scientifique
Phenotypic and functional heterogeneity of peripheral γδ T cells in pulmonary TB and HIV patients in Addis Ababa, Ethiopia
BACKGROUND: Previous studies reported HIV infection alters the distribution and function of γδ T cells and their subsets. γδ T …
Article scientifique
Upper respiratory infections in a rural area with reduced malaria transmission in Senegal: a pathogens community study
BACKGROUND: Acute Respiratory Infections (ARI) are common causes of febrile illnesses in many settings in Senegal. These infections are usually …
Article scientifique
Syphilis reinfection is associated with an attenuated immune profile in the same individual: a prospective observational cohort study
BACKGROUND: Ascertaining if the clinical and immunological response to repeat syphilis differs from that in initial syphilis may assist in …
Article scientifique
Assessing the impact of antiretroviral therapy on tuberculosis notification rates among people with HIV: a descriptive analysis of 23 countries in sub-Saharan Africa, 2010–2015
BACKGROUND: HIV is a major driver of the tuberculosis epidemic in sub-Saharan Africa. The population-level impact of antiretroviral therapy (ART) …
Article scientifique
Current treatment of multidrug resistant tuberculosis in Ethiopia: an aggregated and individual patients’ data analysis for outcome and effectiveness of the current regimens
BACKGROUND: The programmatic management of Multidrug-resistant tuberculosis (MDR-TB) is entirely based on a WHO recommended long-term, 18-24 month lasting treatment …
Article scientifique
Incubation period of typhoidal salmonellosis: a systematic review and meta-analysis of outbreaks and experimental studies occurring over the last century
Salmonella Typhi is a human pathogen that causes typhoid fever. It is a major cause of morbidity and mortality in …
Article scientifique
Contamination of microbial pathogens and their antimicrobial pattern in operating theatres of peri-urban eastern Uganda: a cross-sectional study
BACKGROUND: Microbial contamination of hospital environment, especially in operating theatres (OT) and other specialized units has greatly contributed to continuous …
Article scientifique
Prevalence and risk factors of tungiasis among children of Wensho district, southern Ethiopia
BACKGROUND: Tungiasis is an ectoparasitic infestation, which still has public health importance in deprived populations of developing countries. Data on …
Article scientifique
Seroprevalence of hepatitis B virus infection and associated factors among healthcare workers in northern Tanzania
Hepatitis B virus infection is a global health problem with the highest prevalence in East Asia and Sub-Saharan Africa. The …
Article scientifique
Impact of alcohol consumption on tuberculosis treatment outcomes: a prospective longitudinal cohort study protocol
BACKGROUND: An estimated 10% of tuberculosis (TB) deaths are attributable to problematic alcohol use globally, however the causal pathways through …
Article scientifique
Virological failure among adolescents on ART, Harare City, 2017- a case-control study
BACKGROUND: Zimbabwe is on track towards achieving viral suppression among adults (87%). However, adolescents have only achieved 44% by 2016. …
Article scientifique
Exceptional association of two species of bacteria causing mediastinitis: Haemophilus influenzae (H. influenzae) and Aggregatibacter aphrophilus (A. aphrophilus)
BACKGROUND: Post cardiac surgery mediastinitis is the major infectious complication, despite the development of surgical techniques and the application of …
Article scientifique
Low prevalence of lipodystrophy in HIV-infected Senegalese children on long-term antiretroviral treatment: the ANRS 12279 MAGGSEN Pediatric Cohort Study
BACKGROUND: The long-term benefits of antiretroviral treatment (ART) are associated with metabolic complications, especially lipodystrophy, which has been well described …
Article scientifique
Spectrum of disease in HIV-positive patients presenting to a tertiary care hospital: a retrospective, cross-sectional review in Kumasi, Ghana
BACKGROUND: HIV remains a significant public health dilemma in West and Central Africa. HIV-related morbidity and mortality are unjustly high, …
Article scientifique
Evidence of human leptospirosis cases in a cohort of febrile patients in Bangui, Central African Republic: a retrospective study, 2012–2015
BACKGROUND: In spite of a local favorable environment, leptospirosis has never been described in Central African Republic so far mainly …
Article scientifique
Epidemiology of measles in the metropolitan setting, Addis Ababa, Ethiopia, 2005–2014: a retrospective descriptive surveillance data analysis
BACKGROUND: Measles is a highly infectious and serious respiratory viral disease which caused by a virus. It is a significant …