1373 publication(s) trouvée(s)
Article scientifique
Measuring influenza laboratory capacity: use of a tool to measure improvements
BACKGROUND: To collect information, identify training needs, and assist with influenza capacity building voluntary laboratory capacity assessments were conducted using …
Article scientifique
Misdiagnosis of HIV treatment failure based on clinical and immunological criteria in Eastern and Central Kenya
BACKGROUND: Routine laboratory monitoring is part of the basic care package offered to people living with the Human Immunodeficiency Virus …
Article scientifique
Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert® MTB/RIF era: a cohort study
BACKGROUND: The Xpert™ MTB/RIF (XP) has a higher sensitivity than sputum smear microscopy (70% versus 35%) for TB diagnosis and …
Article scientifique
Comparison of apoptosis in human primary pulmonary endothelial cells and a brain microvascular endothelial cell line co-cultured with Plasmodium falciparum field isolates
BACKGROUND: Plasmodium falciparum infection can progress unpredictably to severe forms including respiratory distress and cerebral malaria. The mechanisms underlying the …
Article scientifique
Joint Bayesian modeling of time to malaria and mosquito abundance in Ethiopia
BACKGROUND: This paper studies the effect of mosquito abundance and malaria incidence in the last 3 weeks, and their interaction, …
Article scientifique
Multi-state models for the analysis of time-to-treatment modification among HIV patients under highly active antiretroviral therapy in Southwest Ethiopia
BACKGROUND: Highly active antiretroviral therapy (HAART) has shown a dramatic change in controlling the burden of HIV/AIDS. However, the new …
Article scientifique
Antiretroviral therapy initiation within seven days of enrolment: outcomes and time to undetectable viral load among children at an urban HIV clinic in Uganda
BACKGROUND: Viral suppression is a critical indicator of HIV treatment success. In the era of test-and-start, little is known about …
Article scientifique
Isolation, biochemical and molecular identification of Nocardia species among TB suspects in northeastern, Tanzania; a forgotten or neglected threat?
BACKGROUND: Pulmonary nocardiosis mimic pulmonary tuberculosis in most clinical and radiological manifestations. In Tanzania, where tuberculosis is one of the …
Article scientifique
Peripheral neuropathy in a diabetic child treated with linezolid for multidrug-resistant tuberculosis: a case report and review of the literature
BACKGROUND: Extensively drug-resistant (XDR) tuberculosis (TB) and multidrug resistant (MDR)-TB with additional resistance to injectable agents or fluoroquinolones are challenging …
Article scientifique
Assessing the knowledge of expectant mothers on mother–to-child transmission of viral hepatitis B in Upper West region of Ghana
BACKGROUND: Viral Hepatitis B is of a major public health concern globally, especially in developing countries. Expectant mothers' knowledge of …
Article scientifique
Development and validation of a risk score to assist screening for acute HIV-1 infection among men who have sex with men
BACKGROUND: Early treatment of acute HIV-1 infection (AHI) is beneficial for patients and could reduce onward transmission. However, guidelines on …
Article scientifique
Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa
BACKGROUND: Anaemia is common in malaria. It is important to quantitate the risk of anaemia and to distinguish factors related …
Article scientifique
Early experiences from one of the first treatment programs for chronic hepatitis B in sub-Saharan Africa
BACKGROUND: Treatment for chronic hepatitis B (CHB) is virtually absent in sub-Saharan Africa. Here we present early experiences from a …
Article scientifique
Risk factors of lower limb cellulitis in a level-two healthcare facility in Cameroon: a case-control study
BACKGROUND: Cellulitis is a common infection of the skin and subcutaneous tissues. It is associated with significant morbidity from necrosectomies …
Article scientifique
Performance comparison of CareStart™ HRP2/pLDH combo rapid malaria test with light microscopy in north-western Tigray, Ethiopia: a cross-sectional study
BACKGROUND: Rapid diagnostic tests (RDTs) are alternative methods for microscopy in the diagnosis of malaria in resource limited settings. Among …
Article scientifique
Prevalence and risk factors for latent tuberculosis infection among healthcare workers in Nampula Central Hospital, Mozambique
BACKGROUND: Healthcare workers in high tuberculosis burdened countries are occupationally exposed to the tuberculosis disease with uncomplicated and complicated tuberculosis …
Article scientifique
Spatial patterns of childhood diarrhea in Ethiopia: data from Ethiopian demographic and health surveys (2000, 2005, and 2011)
BACKGROUND: Childhood diarrhea is a major public health problem, especially in developing countries, including Ethiopia. Exploring the spatial pattern of …
Article scientifique
Risk factors, person, place and time characteristics associated with Hepatitis E Virus outbreak in Napak District, Uganda
BACKGROUND: Hepatitis E is self-limiting, but can cause death in most at risk groups like pregnant women and those with …
Article scientifique
Prevalence and molecular characteristics of Staphylococcus aureus, including methicillin resistant strains, isolated from bulk can milk and raw milk products in pastoral communities of South-West Uganda
BACKGROUND: Staphylococcus aureus strains are now regarded as zoonotic agents. In pastoral settings where human-animal interaction is intimate, multi-drug resistant …
Article scientifique
An integrated study of human and animal infectious disease in the Lake Victoria crescent small-holder crop-livestock production system, Kenya
BACKGROUND: The neglected zoonotic diseases (NZD) are an understudied group that are a major cause of illness throughout the developing …