168 publication(s) trouvée(s)
Article scientifique
Is trofinetide a future treatment for Rett syndrome? A comprehensive systematic review and meta-analysis of randomized controlled trials
BACKGROUND: Rett syndrome (RTT) is a rare, life-threatening, genetic neurodevelopmental disorder. Treatment in RTT encounters many challenges. Trofinetide, a modified …
Article scientifique
The impact of the COVID-19 pandemic on tuberculosis treatment outcomes in 49 high burden countries
BACKGROUND: The COVID-19 pandemic disrupted tuberculosis (TB) health services, including treatment support and access to drugs, as patients were not …
Erratum
Correction: Transient increased risk of influenza infection following RSV infection in South Africa: findings from the PHIRST study, South Africa, 2016–2018
Article scientifique
Malaria vaccination: hurdles to reach high-risk children
Ensuring that malaria vaccines deliver maximum public health impact is non-trivial. Drawing on current research, this article examines hurdles that …
Article scientifique
Association of in utero HIV exposure with child brain structure and language development: a South African birth cohort study
BACKGROUND: There is a growing population of children with in utero HIV exposure who are at risk of poor neurodevelopmental …
Article scientifique
Mapping heterogeneity in family planning indicators in Burkina Faso, Kenya, and Nigeria, 2000–2020
BACKGROUND: Family planning is fundamental to women's reproductive health and is a basic human right. Global targets such as Sustainable …
Article scientifique
Strategies for addressing the needs of children with or at risk of developmental disabilities in early childhood by 2030: a systematic umbrella review
BACKGROUND: There are over 53million children worldwide under five with developmental disabilities who require effective interventions to support their health …
Article scientifique
Mosquito odour-baited mass trapping reduced malaria transmission intensity: a result from a controlled before-and-after intervention study
BACKGROUND: Conventional vector control strategies have significantly reduced the malaria burden. The sustainability of these methods is currently challenged. Odour-based …
Article scientifique
Performance of a safe and dignified burial intervention during an Ebola epidemic in the eastern Democratic Republic of the Congo, 2018–2019
BACKGROUND: A protracted Ebola Virus Disease (EVD) epidemic in the eastern Ituri, North and South Kivu provinces of the Democratic …
Article scientifique
Transient increased risk of influenza infection following RSV infection in South Africa: findings from the PHIRST study, South Africa, 2016–2018
BACKGROUND: Large-scale prevention of respiratory syncytial virus (RSV) infection may have ecological consequences for co-circulating pathogens, including influenza. We assessed …
Article scientifique
Malnutrition-related mortality trends in older adults in the United States from 1999 to 2020
BACKGROUND: Malnutrition mortality in older adults is underrepresented in scientific literature. This obscures any recent changes and hinders needed social …
Article scientifique
Establishing international optimal cut-offs of waist-to-height ratio for predicting cardiometabolic risk in children and adolescents aged 6–18 years
BACKGROUND: Waist-to-height ratio (WHtR) has been proposed as a simple and effective screening tool for assessing central obesity and cardiometabolic …
Article scientifique
Factors affecting haemoglobin dynamics in African children with acute uncomplicated Plasmodium falciparum malaria treated with single low-dose primaquine or placebo
BACKGROUND: Single low-dose primaquine (SLDPQ) effectively blocks the transmission of Plasmodium falciparum malaria, but anxiety remains regarding its haemolytic potential …
Article scientifique
Impacts of performance-based financing on health system performance: evidence from the Democratic Republic of Congo
BACKGROUND: Health systems' weakness remains one of the primary obstacles towards achieving universal access to quality healthcare in low-income settings. …
Article scientifique
Five-year results of a treatment program for chronic hepatitis B in Ethiopia
BACKGROUND: In sub-Saharan Africa, less than 1% of treatment-eligible chronic hepatitis B (CHB) patients receive antiviral therapy. Experiences from local …
Article scientifique
Early neuro-rehabilitation in traumatic brain injury: the need for an African perspective
BACKGROUND: Traumatic brain injury (TBI) is a global public health challenge, affecting about 69 million individuals annually and being one …
Article scientifique
Informing a target product profile for rapid tests to identify HBV-infected pregnant women with high viral loads: a discrete choice experiment with African healthcare workers
BACKGROUND: Elimination of mother-to-child transmission of hepatitis B virus (HBV) requires infant immunoprophylaxis and antiviral prophylaxis for pregnant women with …
Article scientifique
Housing modification for malaria control: impact of a “lethal house lure” intervention on malaria infection prevalence in a cluster randomised control trial in Côte d’Ivoire
BACKGROUND: In recent years, the downward trajectory of malaria transmission has slowed and, in some places, reversed. New tools are …
Article scientifique
The burden of RSV-associated illness in children aged < 5 years, South Africa, 2011 to 2016
BACKGROUND: Vaccines and monoclonal antibodies to protect the very young infant against the respiratory syncytial virus (RSV)-associated illness are effective …
Article scientifique
The economic burden of RSV-associated illness in children aged < 5 years, South Africa 2011–2016
BACKGROUND: Data on the economic burden of RSV-associated illness will inform decisions on the programmatic implementation of maternal vaccines and …