41 publication(s) trouvée(s)
Article scientifique
Soluble triggering receptor expressed on myeloid cells 1 (sTREM-1) predicts mortality in patients with febrile illness in southern Mozambique
BACKGROUND: Fever is a leading reason for seeking healthcare globally. Early in the course of febrile illness, it is challenging …
Article scientifique
Cancer Research Funding in Africa
BACKGROUND: Africa is projected to witness the steepest rise in cancer incidence and mortality in the coming decades. Therefore, it …
Article scientifique
High diversity of Escherichia coli causing invasive disease in neonates in Malawi poses challenges for O-antigen based vaccine approach
BACKGROUND: Escherichia coli is an important cause of neonatal sepsis and the third most prevalent cause of neonatal infection in …
Article scientifique
Mapping and quantifying travel time to define health facility catchment areas in Blantyre city in Malawi
BACKGROUND: Mapping health facility catchment areas is important for estimating the population that uses the health facility, as a denominator …
Article scientifique
An analysis of One Health timeliness metrics across multisectoral public health emergencies in Uganda
BACKGROUND: Timeliness metrics offer countries a framework by which to assess and optimize speed in outbreak detection and response times. …
Article scientifique
Compartmentalised mucosal and blood immunity to SARS-CoV-2 is associated with high seroprevalence before the Delta wave in Africa
BACKGROUND: The reported number of SARS-CoV-2 cases and deaths are lower in Africa compared to many high-income countries. However, in …
Article scientifique
Analysis of travel-time to HIV treatment in sub-Saharan Africa reveals inequities in access to antiretrovirals
BACKGROUND: UNAIDS proposes ending inequalities in access to HIV treatment. We use data from nationally-representative Population-Based HIV Impact Assessment (PHIA) …
Article scientifique
A public health call for action to address liver cancer and hepatitis in northern Ghana
April 2024 saw the World Health Organization (WHO) release of the Global hepatitis report 2024: action for access in low- …
Article scientifique
Hydroxyurea mobile directly observed therapy versus standard monitoring in patients with sickle cell anemia: a phase 2 randomized trial
BACKGROUND: Sickle cell anemia (SCA) prevalence remains high in sub-Saharan Africa. Long-term treatment with hydroxyurea (HU) increases survival, however, poor …
Article scientifique
Household-level effects of seasonal malaria chemoprevention in the Gambia
BACKGROUND: In 2022 the WHO recommended the discretionary expansion of the eligible age range for seasonal malaria chemoprevention (SMC) to …
Article scientifique
Genomics reveals heterogeneous Plasmodium falciparum transmission and selection signals in Zambia
BACKGROUND: Genomic surveillance is crucial for monitoring malaria transmission and understanding parasite adaptation to interventions. Zambia lacks prior nationwide efforts …
Article scientifique
Socio-spatial equity analysis of relative wealth index and emergency obstetric care accessibility in urban Nigeria
BACKGROUND: Better geographical accessibility to comprehensive emergency obstetric care (CEmOC) facilities can significantly improve pregnancy outcomes. However, with other factors, …
Article scientifique
Substantial but spatially heterogeneous progress in male circumcision for HIV prevention in South Africa
BACKGROUND: Voluntary medical male circumcision (VMMC) reduces the risk of male HIV acquisition by 60%. Programmes to provide VMMCs for …
Article scientifique
A geospatial analysis of accessibility and availability to implement the primary healthcare roadmap in Ethiopia
BACKGROUND: Primary healthcare (PHC) is a crucial strategy for achieving universal health coverage. Ethiopia is working to improve its primary …
Article scientifique
Intestinal disturbances associated with mortality of children with complicated severe malnutrition
BACKGROUND: Children admitted to hospital with complicated severe malnutrition (CSM) have high mortality despite compliance with standard WHO management guidelines. …
Article scientifique
Acquisition and carriage of genetically diverse multi-drug resistant gram-negative bacilli in hospitalised newborns in The Gambia
BACKGROUND: This detailed genomic study characterised multi-drug resistant-Gram negative bacilli (MDR-GNB) carriage in neonates < 2 kg and paired mothers …
Article scientifique
Why and how a university in Rwanda is training its medical students in one health
The One Health approach considers the contribution of animals and the environment to health. Here we describe how the University …
Article scientifique
A mobile-optimized artificial intelligence system for gestational age and fetal malpresentation assessment
Abstract Background Fetal ultrasound is an important component of antenatal care, but shortage of adequately trained healthcare workers has limited …
Article scientifique
Differences between gridded population data impact measures of geographic access to healthcare in sub-Saharan Africa
Background: Access to healthcare is imperative to health equity and well-being. Geographic access to healthcare can be modeled using spatial …
Article scientifique
Temporal lineage replacements and dominance of imported variants of concern during the COVID-19 pandemic in Kenya
Background: Kenya's COVID-19 epidemic was seeded early in March 2020 and did not peak until early August 2020 (wave 1), …