64 publication(s) trouvée(s)
Article scientifique
Fezolinetant’s efficacy and safety in treatment of vasomotor symptoms in postmenopausal women: a meta-analysis and GRADE evaluation of randomized controlled trials
BACKGROUND: Postmenopausal women are more likely to experience vasomotor symptoms (VMS), such as heat sensation and sweating. Recent trials have …
Article scientifique
CYP3A4*1B and CYP3A5*3 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin
BACKGROUND: A single nucleotide polymorphism (SNP) is a variation in the DNA sequence that results from the alteration of a …
Article scientifique
Parasites revive hope for cancer therapy
Parasites have attained a life-long stigma of being detrimental organisms with deleterious outcomes. Yet, recently, a creditable twist was verified …
Article scientifique
Diagnostic performance of new BAST score versus FIB-4 index in predicating of the liver fibrosis in patients with metabolic dysfunction-associated steatotic liver disease
BACKGROUND AND AIM: Metabolic dysfunction-associated steatotic liver disease (MASLD) formerly known as non-alcoholic fatty liver disease (NAFLD) is the most …
Article scientifique
Steady-state pharmacokinetics of lamivudine in end-stage kidney failure persons with detectable and undetectable HIV-1 RNA in peritoneal dialysis effluent
Abstract Background Renally adjusted lamivudine dosages are effective. However, some of the kidney failure patients managed with lamivudine-containing regimens are …
Article scientifique
Assessment of interleukin-18 gene polymorphism and serum levels in cutaneous lichen planus
BACKGROUND: Lichen planus (LP) is a chronic inflammatory disease with uncertain etiology. Interleukin-18 (IL-18) is an interferon gamma (INFγ) inducing …
Article scientifique
Dyslipidemia and associated factors among adult cardiac patients: a hospital-based comparative cross-sectional study
BACKGROUND: Atherosclerotic vascular diseases are a leading global cause of morbidity and mortality. Dyslipidemia, a major modifiable risk factor for …
Article scientifique
CD4+ T cell count and HIV-1 viral load dynamics positively impacted by H. pylori infection in HIV-positive patients regardless of ART status in a high-burden setting
Abstract Background There is a widespread co-infection of HIV and Helicobacter pylori (H. pylori) globally, particularly in developing countries, and …
Article scientifique
The efficacy and safety of cannabidiol (CBD) in pediatric patients with Dravet Syndrome: a narrative review of clinical trials
BACKGROUND: Dravet Syndrome (DS) is a rare and severe form of childhood epilepsy that is often refractory to conventional antiepileptic …
Article scientifique
The efficacy of tixagevimab/cilgavimab (Evusheld) in prophylaxis and treatment of COVID-19 in immunocompromised patients: a systematic review and meta-analysis
BACKGROUND: During the COVID-19 pandemic, some populations, including immunocompromised patients, could not tolerate COVID-19 vaccination or had low responses. Evusheld …
Article scientifique
Nanotechnology in leukemia: diagnosis, efficient-targeted drug delivery, and clinical trials
Leukemia is a group of malignant disorders which affect the blood and blood-forming tissues in the bone marrow, lymphatic system, …
Article scientifique
Novel CAD–CAM fabrication of a custom-made ball attachment retentive housing: an in-vitro study
PURPOSE: This study aims to evaluate the digitally designed ball attachment housing in its initial retentive force and after 2 …
Article scientifique
Serum growth differentiation factor-15 (GDF-15) is a biomarker of cardiac manifestations in children with COVID-19
BACKGROUND: COVID-19 leads to severe overwhelming inflammation in some patients mediated by various cytokines (cytokine storm) that usually leads to …
Article scientifique
Current clinical presentations of AIDS dementia in a tropical environment: study of 26 observations in the neurology department of the University Hospital of Conakry
INTRODUCTION: In sub-Saharan Africa (SSA), the clinical and progressive diagnostic certainty of AIDS dementia is difficult to establish due to …
Article scientifique
Predictors of cervical tumour size for outpatients with cervical cancer at the University of Gondar referral hospital: a retrospective study design
Abstract Background Cervical cancer is one of the most serious threats to women's lives. Modelling the change in tumour size …
Article scientifique
Role of tranexamic acid-soaked gelatin sponge in minimizing rectus sheath hematoma after cesarean section in women treated with warfarin, a simple tool for high-risk cases, a randomized controlled trial
BACKGROUND: This study aims to illustrate the impact of applying the tranexamic acid impregnated in a gelatin sponge between the …
Article scientifique
Clinical implications of heat shock protein 70 in oral carcinogenesis and prediction of progression and recurrence in oral squamous cell carcinoma patients: a retrospective clinicopathological study
BACKGROUND: Oral cancer is a common cause of death worldwide. The search for novel biomarkers for oral cancer is an …
Article scientifique
Effectiveness of thyme honey in the management of xerostomia in geriatric patients with end-stage renal disease: a randomized controlled clinical trial with a biochemical assessment
Abstract Background Taking into consideration the value of the oral health condition in geriatric people with end-stage renal disease (ESRD) …
Article scientifique
Respiratory co-infections in COVID-19-positive patients
BACKGROUND: Opportunistic respiratory infections may complicate critically ill patients with COVID-19. Early detection of co-infections helps to administrate the appropriate …
Article scientifique
Intention to use maternal waiting home and its predictors among pregnant women in Ethiopia: systematic review and meta-analysis
Abstract Background A high maternal death rate is a result of maternal delays in seeking emergency obstetric care, particularly in …