29 publication(s) trouvée(s)
Article scientifique
Different Phenotypes in Pseudodominant Inherited Retinal Dystrophies
Retinal dystrophies (RD) are a group of Mendelian disorders caused by rare genetic variations leading to blindness. A pathogenic variant …
Article scientifique
In vitro Characterization of Insulin−Producing β-Cell Spheroids
Over the years, immortalized rodent β-cell lines such as RIN, HIT, MIN, βTC, and INS-1 have been used to investigate …
Article scientifique
Tumor Microenvironment Uses a Reversible Reprogramming of Mesenchymal Stromal Cells to Mediate Pro-tumorigenic Effects
The role of mesenchymal stromal cells (MSCs) in the tumor microenvironment is well described. Available data support that MSCs display …
Article scientifique
Amino Acid Starvation Sensitizes Resistant Breast Cancer to Doxorubicin-Induced Cell Death
Many clinical trials are beginning to assess the effectiveness of compounds known to regulate autophagy in patients receiving anti-cancer chemotherapy. …
Article scientifique
Mesenchymal Stem Cells and Their Extracellular Vesicles: A Potential Game Changer for the COVID-19 Crisis
Corona virus disease 2019 (COVID-19) is a global public health crisis. The high infectivity of the disease even from non-symptomatic …
Article scientifique
Methylomic Changes of Autophagy-Related Genes by Legionella Effector Lpg2936 in Infected Macrophages
Legionella pneumophila is a Gram-negative bacteria that infects human respiratory tract causing Legionaries disease; a severe form of pneumonia. Recently, …
Article scientifique
Therapeutic Potential of Wharton’s Jelly Mesenchymal Stem Cells for Diabetes: Achievements and Challenges
Diabetes mellitus is an alarming metabolic disease in which insulin secreting β-cells are damaged to various extent. Unfortunately, although currently …
Article scientifique
Lnc-ing Trained Immunity to Chromatin Architecture
Human innate immune cells exposed to certain infections or stimuli develop enhanced immune responses upon re-infection with a different second …
Article scientifique
In vitro Culture of Naïve Human Bone Marrow Mesenchymal Stem Cells: A Stemness Based Approach
Human bone marrow derived mesenchymal stem cells (BM-MSCs) resides in their niches in close proximity to hematopoietic stem cells (HSCs). …
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