185 publication(s) trouvée(s)
Article scientifique
Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes
Introduction Streptococcus pneumoniae bacteria cause life-threatening invasive pneumococcal disease (IPD), including meningitis. Pneumococci are classified into serotypes, determined by differences …
Article scientifique
Therapeutic efficacy of dihydroartemisinin-piperaquine combination for the treatment of uncomplicated malaria in Ghana
In 2020, Dihydroartemisinin-Piperaquine (DHAP) was adopted as a second-line antimalarial for treatment of uncomplicated malaria in Ghana following a review …
Article scientifique
Faecal carriage of ESBL producing and colistin resistant Escherichia coli in avian species over a 2-year period (2017-2019) in Zimbabwe
Introduction Extended spectrum beta-lactamase (ESBL) producing Escherichia coli have become widespread among food producing animals. These strains serve as a …
Article scientifique
Biochemical and hematological factors associated with COVID-19 severity among Gabonese patients: A retrospective cohort study
The COVID-19 disease presents a large range of clinical manifestations and includes asymptomatic, mild, and severe cases. The level of …
Article scientifique
Survival and detection of SARS-CoV-2 variants on dry swabs post storage
COVID-19 has resulted in nearly 598 million infections and over 6.46 million deaths since the start of the severe acute …
Article scientifique
The detection of mixed tuberculosis infections using culture filtrate and resuscitation promoting factor deficient filtrate
Tuberculosis (TB) infected individuals harbor a heterogenous population of differentially culturable tubercle bacilli (DCTB). Herein, we describe how DCTB assays …
Article scientifique
The filarial and the antibiotics: Single or combination therapy using antibiotics for filariasis
Filarial infections caused by nematodes are one of the major neglected tropical diseases with public health concern. Although there is …
Article scientifique
Culture filtrate supplementation can be used to improve Mycobacterium tuberculosis culture positivity for spinal tuberculosis diagnosis
Culture remains the gold standard to diagnose spinal tuberculosis (STB) despite the paucibacillary nature of the disease. Current methods can …
Article scientifique
Seroprevalence of Toxoplasma gondii and Neospora caninum in camels recently imported to Egypt from Sudan and a global systematic review
Introduction: Toxoplasma gondii and Neospora caninum are closely related intracellular protozoan parasites of medical and veterinary concern by causing abortions …
Article scientifique
In vitro susceptibility profile of Plasmodium falciparum clinical isolates from Ghana to antimalarial drugs and polymorphisms in resistance markers
Drug resistance in Plasmodium falciparum compromises the effectiveness of antimalarial therapy. This study aimed to evaluate the extent of drug …
Article scientifique
Comparison of interferon gamma release assay and CXCL9 gene expression assay for the detection of Mycobacterium bovis infection in African lions (Panthera leo)
Mycobacterium bovis (M. bovis) infection has been identified in both domestic and wild animals and may threaten the conservation of …
Article scientifique
Longitudinal impact of asymptomatic malaria/HIV-1 co-infection on Plasmodium falciparum gametocyte transcript expression and transmission to Anopheles mosquitoes
Despite significant developments towards malaria reduction, parasite transmission in the common context of HIV-1 co-infection and treatment for one or …
Article scientifique
Short-term cryopreservation and thawing have minimal effects on Plasmodium falciparum ex vivo invasion profile
Ex vivo phenotyping of P. falciparum erythrocyte invasion diversity is important in the identification and down selection of potential malaria …
Article scientifique
Microscopic and submicroscopic infection by Plasmodium falciparum: Immunoglobulin M and A profiles as markers of intensity and exposure
Assessment of serological Plasmodium falciparum–specific antibodies in highly endemic areas provides valuable information about malaria status and parasite exposure in …
Article scientifique
Detection of differentially culturable tubercle bacteria in sputum from drug-resistant tuberculosis patients
Several studies described the presence of non-replicating, drug-tolerant differentially culturable tubercle bacteria (DCTB) in sputum from patients with active tuberculosis …
Article scientifique
Silicone Foley catheters impregnated with microbial indole derivatives inhibit crystalline biofilm formation by Proteus mirabilis
Proteus mirabilis is a common causative agent for catheter-associated urinary tract infections (CAUTI). The crystalline biofilm formation by P. mirabilis …
Article scientifique
Phenotypic adaptation of Mycobacterium tuberculosis to host-associated stressors that induce persister formation
Mycobacterium tuberculosis exhibits a remarkable ability to interfere with the host antimicrobial response. The pathogen exploits elaborate strategies to cope …
Article scientifique
Drug resistant tuberculosis: Implications for transmission, diagnosis, and disease management
Drug resistant tuberculosis contributes significantly to the global burden of antimicrobial resistance, often consuming a large proportion of the healthcare …
Article scientifique
Role of Immunity and Vaginal Microbiome in Clearance and Persistence of Human Papillomavirus Infection
Cervical cancer disproportionately affects women of reproductive age, with 80% of cases occurring in low- and middle-income countries. Persistent infection …
Article scientifique
Genomic and Evolutionary Analysis of Salmonella enterica Serovar Kentucky Sequence Type 198 Isolated From Livestock In East Africa
Since its emergence in the beginning of the 90’s, multidrug-resistant (MDR) Salmonella enterica subsp. enterica serovar Kentucky has become a …