220 publication(s) trouvée(s)
Article scientifique
Epigenetic modifications in solid tumor metastasis in people of African ancestry
This review focuses on the critical role of epigenetic modifications in solid tumor metastasis, particularly in people of African ancestry. …
Article scientifique
Humoral immunoprofiling identifies novel biomarkers and an immune suppressive autoantibody phenotype at the site of disease in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous cancer, with minimal response to therapeutic intervention and with 85% of cases diagnosed …
Article scientifique
Quality of life and associated factors among patients with cancer receiving chemotherapy at Dessie Comprehensive Specialized Hospital, North-East Ethiopia: a cross-sectional study
Background: Cancer is a major public health problem around the world. Cancer by itself and its treatment modalities affect the …
Article scientifique
Aluminium phthalocyanine-mediated photodynamic therapy induces ATM-related DNA damage response and apoptosis in human oesophageal cancer cells
Introduction Photodynamic therapy (PDT) is a light-based technique used in the treatment of malignant and non-malignant tissue. Aluminium-phthalocyanine chloride tetra …
Article scientifique
Drinking patterns, alcoholic beverage types, and esophageal cancer risk in Africa: a comprehensive systematic review and meta-analysis
Africa is the continent most affected by esophageal cancer in the world. Alcoholic beverages are controversially blamed, as esophageal cancer …
Article scientifique
Utilization of cancer immunotherapy in sub-Saharan Africa
Introduction: The Lancet Oncology Commission for sub-Saharan Africa (SSA) predicts that cancer deaths will double from 520,158 per year to …
Article scientifique
Psychosocial distress and associated factors among adult cancer patients at oncology: a case of Ethiopia
Background Psychosocial distress is a chronic burden for cancer survivors, which impacts both their quality of life and their oncologic …
Article scientifique
Lung cancer mortality and associated predictors: systematic review using 32 scientific research findings
Background: Cancer is a chronic disease brought on by mutations to the genes that control our cells' functions and become …
Article scientifique
Pediatric neurosurgical-oncology scope and management paradigms in Sub-Saharan Africa: a collaboration among 7 referral hospitals on the subcontinent
Background: Understanding of the epidemiology and biology of pediatric CNS tumors has advanced dramatically over the last decade; however there …
Article scientifique
Management pattern and medication-related harms and its predictors in colorectal cancer patients: an institutional-based retrospective study
Introduction: Data on colorectal cancer (CRC) patients' thorough management practices and medication-related harms (MRH) are scarce. This study's aim was …
Article scientifique
Cervical cancer screening uptake and associated factors among Women Living with Human Immunodeficiency Virus in public hospitals, eastern Ethiopia
Background: Cervical cancer, the second leading cancer in Ethiopia women, is six times higher among women infected with the Human …
Article scientifique
TP53 Gene 72 Arg/Pro (rs1042522) single nucleotide polymorphism increases the risk and the severity of chronic lymphocytic leukemia
Background Genetic variations in TP53 gene are known to be important in chronic lymphocytic leukemia (CLL) and may cause its …
Article scientifique
Prevalence and risk factors for high-risk human papillomavirus infection among women from three southern geopolitical zones of Nigeria
Introduction: Human Papillomavirus (HPV) infection is a risk factor for cervical cancer, the fourth most common cancer among women globally. …
Éditorial
Editorial: Editor’s challenge: Mohamed Rahouma - how can we optimize the management and treatment of cardiac tumors and cardiac complications of cancer?
Editor's challenge: Mohamed Rahouma -how can we optimize the management and treatment of cardiac tumors and cardiac complications of cancer?Cardiac …
Article scientifique
Yes-associated protein-1 overexpression in ocular surface squamous neoplasia; a potential diagnostic marker and therapeutic target
Yes-associated protein-1 (YAP-1) is a Hippo system transcription factor, which serves as an oncogene in squamous cell carcinoma, and several …
Article scientifique
Photodynamic therapy induced cell cycle arrest and cancer cell synchronization: review
Cell cycle arrest (CCA) is seen as a prime candidate for effective cancer therapy. This mechanism can help researchers to …
Article scientifique
Outcome and toxicity of ifosfamide, carboplatin, and etoposide versus gemcitabine and vinorelbine regimen for pediatric patients with relapsed or refractory Hodgkin’s lymphoma
Background: Pediatric classical Hodgkin lymphoma (CHL) is a curable disease; however, the optimal salvage regimen is unclear for relapsed/refractory (R/R) …
Article scientifique
Breast self-examination practice and associated factors among women of reproductive age in southeast Ethiopia
Regular breast self-examination is the most cost-effective method for early detection of breast cancer, especially in resource-limited countries. However, breast …
Article scientifique
Effects of Adriamycin-Cytoxan chemotherapy on hematological and electrolyte parameters among breast cancer patients
Background Adriamycin-Cytoxan (AC) is a common chemotherapy treatment for breast cancer (BC) patients. Its electrolyte and hematological adverse effects have …
Article scientifique
Deciphering immune microenvironment and cell evasion mechanisms in human gliomas
Gliomas are considered one of the most malignant cancers in the body. Despite current therapies, including surgery, chemotherapy, and radiotherapy, …