272 publication(s) trouvée(s)
Article scientifique
Impact of COVID-19 on neglected tropical diseases in Zambia: a qualitative study of stakeholder perspectives
BACKGROUND: Neglected tropical diseases (NTDs) remain a major public health challenge in Zambia and other low‑ and middle‑income countries, and …
Article scientifique
Phytochemical synergy in artemisia annua herbal tea against malaria: a systematic review of its efficacy and safety in the context of emerging Pfkelch13 resistance
BACKGROUND: Emerging Plasmodium falciparum resistance to artemisinin derivatives, mediated principally by mutations in the Pfkelch13 propeller domain, is reshaping the …
Article scientifique
Contrasting patterns of trematode and host snail dispersal across clusters of tropical crater lakes
Abstract Background Comparing the genetic diversity and population structure of parasites and their hosts can improve understanding of their respective …
Article scientifique
Prevalence, determinants, and wealth-related inequalities in malaria among under five children in Uganda: evidence from the malaria indicator survey
BACKGROUND: Malaria remains a leading cause of morbidity and mortality among children under five in Uganda. Despite national control efforts, …
Article scientifique
An ensemble machine learning approach for predicting anemia among under-five children in malaria-endemic sub-Saharan African countries
BACKGROUND: Worldwide, anemia in children under-five is a major public health issue, particularly in sub-Saharan Africa. Sub-Saharan Africa also has …
Article scientifique
Short-term health system responses to epidemics across hard-to-reach areas in sub-Saharan Africa: a scoping review
BACKGROUND: Epidemics and disease outbreaks continue to threaten public health security in sub-Saharan Africa (SSA), disproportionately impacting impoverished and hard-to-reach …
Article scientifique
Climate justice as a public health imperative: a perspective from Sierra Leone considering the 2025 International Court of Justice opinion
Climate change poses an escalating threat to health, livelihoods, and economic development in Sierra Leone, a coastal, low-income country highly …
Article scientifique
Determining spatio-temporal distribution and hotspots for female schistosomiasis in Ghana, 2020–2024: a call for increased public health action against a neglected tropical disease
BACKGROUND: Schistosomiasis remains a major neglected tropical disease in Ghana with substantial health and social consequences for women and girls. …
Article scientifique
Diagnostic accuracy of plasma cell-free DNA qPCR for Schistosoma haematobium assessed by Bayesian latent class analysis in a cohort of pregnant women from Lambaréné, Gabon
BACKGROUND: Effective diagnosis of Schistosoma haematobium is critical for disease management. However, current tools often lack sensitivity for low-intensity infections, …
Article scientifique
Signature of resistance gene evolution and pyrethroid resistance escalation in the major malaria vector Anopheles funestus across Kenyan malaria-endemic regions separated by the Rift Valley
BACKGROUND: Landscape features such as the Rift Valley (RV) can restrict gene flow in malaria vectors and influence resistance patterns. …
Article scientifique
Comparative evaluation of Sm1-7-qPCR systems incorporated with Maxwell kit-based and NaOH-based DNA extraction methods for the detection of Schistosoma mansoni infection
Abstract Background The World Health Organization’s latest roadmap for neglected tropical diseases (NTDs) 2021–2030 has highlighted diagnostics as one of …
Article scientifique
Coverage validation survey of preventive chemotherapy for schistosomiasis in interruption of transmission districts of Ethiopia, 2025
BACKGROUND: Ethiopia bears a substantial burden of neglected tropical diseases, including schistosomiasis, which remains a major public health problem in …
Article scientifique
Diagnostic challenges of histidine-rich protein 2-based rapid diagnostic tests due to pfhrp2 and pfhrp3 gene deletions in asymptomatic malaria in Tanzania
Abstract Background Histidine-rich protein 2 (HRP2)-based rapid diagnostic tests (RDTs) are critical for malaria diagnosis in Africa, particularly in resource-limited …
Article scientifique
From dogma to data: charting a path forward for clinico-immunological research in Ethiopian cutaneous leishmaniasis
BACKGROUND: Rooted in long-standing assumptions and adapted from classifications mainly used for Latin American cutaneous leishmaniasis (CL), the nationally recommended …
Article scientifique
Prevalence, risk factors and trends of human schistosomiasis in Côte d’Ivoire from 1974–2023: systematic review and meta-analysis
Abstract Background Schistosomiasis is a parasitic worm infection that affects an estimated 250 million people. In Côte d’Ivoire, schistosomiasis remains …
Article scientifique
First report of pfhrp2 and pfhrp3 gene deletions compromising HRP2-based malaria rapid diagnostic tests in Malawi
BACKGROUND: Histidine Rich Protein 2-based rapid diagnostic tests (HRP2-based RDTs) are widely used for malaria diagnosis in Malawi, but their …
Article scientifique
An exploratory study to assess the influence of schistosomiasis on the occurrence of dengue virus in Madagascar
BACKGROUND: Dengue virus (DENV) is the most prevalent mosquito-borne virus worldwide, with approximately half of the world's population at risk …
Article scientifique
Harnessing community-based one health interventions implementation beyond Mpox outbreak management in Africa: insights and benefits
BACKGROUND: Little is documented on key community-based One Health (OH) approach implementation, pro-activeness and effectiveness of interactions and strategies against …
Article scientifique
Chronic kidney disease related to Loa loa microfilaremia in a rural area of the Republic of Congo: a population-based cross-sectional study
BACKGROUND: Loiasis affects millions in Central Africa and, though historically considered benign, emerging data suggest possible renal involvement. This study …
Article scientifique
Malaria-anemia comorbidity and its determinants among pregnant women in high- and moderate-malaria-risk countries in Sub-Saharan Africa
BACKGROUND: Malaria and anemia remain a major public health problem in Sub-Saharan Africa, with pregnant women being particularly vulnerable to …
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