51 publication(s) trouvée(s)
Article scientifique
Comparative Blood-Based Transcriptomic Profiles of Prostate Cancer Patients from South Africa and the USA: A Cross-Sectional Pilot Study
Prostate cancer (PCa) is a major health problem worldwide with variable incidence, progression and outcomes depending on genetic, environmental and …
Article scientifique
Hybrid Model with Wavelet Decomposition and EfficientNet for Accurate Skin Cancer Classification
Faced with anomalies in medical images, Deep learning is facing major challenges in detecting, diagnosing, and classifying the various pathologies …
Article scientifique
Construction of the metabolism-related models for predicting prognosis and infiltrating immune phenotype in lung squamous cell carcinoma
Purpose: Cancers often display disorder metabolism, which closely related to the poor outcome of patients.We aimed to establish prognostic models …
Article scientifique
Anti-PRL-3 Monoclonal Antibody inhibits the Growth and Metastasis of colorectal adenocarcinoma
Background: Colon cancer is the one of leading causes of cancer-related death.Chemotherapy, radiotherapy and immunotherapy will be the mainstream in …
Article scientifique
Prognostic Impact of Long-term Postoperative Pneumonia in Elderly Patients with Early Gastric Cancer
Background: Elderly patients with stage I gastric cancer, a disease that is curable by surgery, easily develop long-term postoperative pneumonia …
Article scientifique
New Clues to Prognostic Biomarkers of Four Hematological Malignancies
Globally, one out of every two reported cases of hematologic malignancies (HMs) results in death.Each year approximately 1.24 million cases …
Article scientifique
Helicobacter pylori associated aberrant methylation genes in blood leukocyte and gastric mucosa
Background and Aim: Methylation alterations may be involved in Helicobacter pylori-associated gastric carcinogenesis. This study aims to explore the potential …
Article scientifique
N6-methyladenosine regulates ATM expression and downstream signaling
N6-methyladenosine (m6A) is the most abundant modification in eukaryotic mRNAs, which plays an important role in regulating multiple biological processes. …
Article scientifique
Mucin 1 promotes tumor progression through activating WNT/β-catenin signaling pathway in intrahepatic cholangiocarcinoma
Background: Current treatment options for intrahepatic cholangiocarcinoma (ICC) are limited by the lack of understanding of the disease pathogenesis. It …
Article scientifique
Antiproliferative, Apoptotic Effects and Suppression of Oxidative Stress of Quercetin against Induced Toxicity in Lung Cancer Cells of Rats: In vitro and In vivo Study
In the present study, quercetin was examined against lung human cancer cells using A549 and H69 cancer cell lines in …
Article scientifique
Safety, Efficacy, Pharmacokinetic and Pharmacodynamic evaluation of YF-H-2015005 for mobilizing Hematopoietic stem cells in Non-Hodgkin's Lymphoma Patients
Background: Targeting the interaction between SDF1 and CXCR4 may provide an opportunity to intervene in the hematopoietic stem cell mobilization …
Article scientifique
The characteristics and long-term survival of patients with colorectal liver metastases with pathological complete response after chemotherapy
Purpose: Preoperative chemotherapy is widely used for colorectal liver metastasis (CRLM). Pathological complete response (PCR) after chemotherapy indicates complete tumor …
Article scientifique
Efficacy and Safety of Fulvestrant 500mg in Hormone-receptor Positive Human Epidermal Receptor 2 Negative Advanced Breast Cancer: A Real-world Study in China
Fulvestrant is an effective, safe and well-tolerated treatment regimen in endocrine therapy for HR+/HER2- metastatic breast cancer. Light tumor burden, …
Article scientifique
A Novel Pre-treatment Model Predicting Risk of Developing Refractoriness to Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma
Background and aim: Refractoriness to transarterial chemoembolization is common during the therapeutic process of hepatocellular carcinoma, which is an intractable …
Article scientifique
Albumin-to-Alkaline Phosphatase Ratio is an Independent Prognostic Indicator in Combined Hepatocellular and Cholangiocarcinoma
The clinical significance of Albumin-to-Alkaline Phosphatase Ratio (AAPR) has been discussed in hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC). The aim …
Article scientifique
CK19-positive Hepatocellular Carcinoma is a Characteristic Subtype
The heterogeneity of hepatocellular carcinoma (HCC) commonly leads to therapeutic failure of HCC. Cytokeratin 19 (CK19) is well acknowledged as …
Article scientifique
Epstein Barr Virus Associated Lymphomas and Epithelia Cancers in Humans
Epstein Barr virus (EBV) is a cosmopolitan oncogenic virus, infecting about 90% of the world's population and it is associated …
Article scientifique
FOXM1 functions collaboratively with PLAU to promote gastric cancer progression
Background: Gastric cancer (GC) is one of the main mortality cause worldwide. Previously, we found Forkhead box protein (FOXM1) or …
Article scientifique
The impact of Ki-67 in the context of multidisciplinary care in primary inflammatory breast cancer
Background: Research on the prognostic or predictive value of Ki-67 among patients with inflammatory breast cancer (IBC) is limited. Methods: …
Article scientifique
A Meta-Analysis of Higher-risk Myelodysplastic Syndrome Trials to Evaluate the Relationship between Short-term Endpoints and Overall Survival
The objective of this work was to evaluate the relationship between the response rates and median overall survival (OS) in …
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