221 publication(s) trouvée(s)
Article scientifique
Correlating SFTPC gene variants to interstitial lung disease in Egyptian children
BACKGROUND: Interstitial lung disease (ILD) is a broad heterogeneous group of lung disorders that is characterized by inflammation of the …
Article scientifique
Impact of rs11024102 PLEKHA7, rs3753841 COL11A1 single nucleotide polymorphisms, and serum levels of oxidative stress markers on the risk of primary angle-closure glaucoma in Egyptians
BACKGROUND: Primary angle-closure glaucoma (PACG) is one of the major causes of blindness in the Middle East with genetic loci …
Article scientifique
Osteogenic enhancement of modular ceramic nanocomposites impregnated with human dental pulp stem cells: an approach for bone repair and regenerative medicine
BACKGROUND/AIM: Human dental pulp-derived mesenchymal stem cells (hDP-MSCs) are a promising source of progenitor cells for bone tissue engineering. Nanocomposites …
Article scientifique
Association study of HIF-1α rs11549465 and VEGF rs3025039 genetic variants with diabetic retinopathy in Egyptian patients: crosslinks with angiogenic, inflammatory, and anti-inflammatory markers
BACKGROUND: Genetic factors are implicated in the progression of DR-a global cause of blindness. Hence, the current work investigated the …
Article scientifique
Polyhydroxyalkanoate recovery from newly screened Bacillus sp. LPPI-18 using various methods of extraction from Loktak Lake sediment sample
BACKGROUND: Nowadays, the conventional plastic wastes are very challenging to environments and its production cost also creates an economic crisis …
Article scientifique
Efficient generation of functional pancreatic β cells from dental-derived stem cells via laminin-induced differentiation
BACKGROUND: This study was designed to generate functional insulin-producing cells (IPCs) from dental-derived mesenchymal stem cells (MSCs) and further explore …
Article scientifique
Stable, efficient, and cost-effective system for the biosynthesis of recombinant bacterial cellulose in Escherichia coli DH5α platform
BACKGROUND: Owing to its remarkable mechanical properties that surpass the plant-based cellulose, bacterial cellulose production has been targeted for commercialization …
Article scientifique
Hesperidin abrogates bisphenol A endocrine disruption through binding with fibroblast growth factor 21 (FGF-21), α-amylase and α-glucosidase: an in silico molecular study
BACKGROUND: Fibroblast growth factor 21 (FGF-21), alpha-amylase, and alpha-glucosidase are key proteins implicated in metabolic dysregulations. Bisphenol A (BPA) is …
Article scientifique
QSAR, homology modeling, and docking simulation on SARS-CoV-2 and pseudomonas aeruginosa inhibitors, ADMET, and molecular dynamic simulations to find a possible oral lead candidate
In seek of potent and non-toxic iminoguanidine derivatives formerly assessed as active Pseudomonas aeruginosa inhibitors, a combined mathematical approach of …
Erratum
Correction: Immunoinformatics approach of epitope prediction for SARS-CoV-2
Article scientifique
Analysis of selected polymorphisms in FOXP3 gene in a cohort of Egyptian patients with schizophrenia
BACKGROUND: Schizophrenia is a chronic mental disorder with different symptoms. The environmental and genetic factors are suggested to be the …
Article scientifique
Genome sequencing reveals existence of SARS-CoV-2 B.1.1.529 variant in Egypt
BACKGROUND: Several SARS-CoV-2 variants with increased transmissibility and/or potential immune escape have emerged and rapidly spread worldwide. Ongoing surveillance analyses …
Article scientifique
The potential role of miR-27a and miR-320a in metabolic syndrome in obese Egyptian females
BACKGROUND: Metabolic syndrome (MetS) is a combination of many health complications, such as obesity, high blood pressure, hyperlipidemia, hyperglycemia, and …
Article scientifique
Molecular characterization of endophytic and ectophytic plant growth promoting bacteria isolated from tomato plants (Solanum lycopersicum L.) grown in different soil types
BACKGROUND: Successful rhizosphere colonization by plant growth promoting rhizobacteria (PGPR) is of crucial importance to perform the desired plant growth …
Article scientifique
Immunoinformatics approach of epitope prediction for SARS-CoV-2
BACKGROUND: The novel coronavirus (SARS-CoV-2) caused lethal infections worldwide during an unprecedented pandemic. Identification of the candidate viral epitopes is …
Article scientifique
A local Talaromyces atroroseus TRP-NRC isolate: isolation, genetic improvement, and biotechnological approach combined with LC/HRESI-MS characterization, skin safety, and wool fabric dyeing ability of the produced red pigment mixture
BACKGROUND: During the last decade, enormous research efforts have been directed at identifying potent microorganisms as sustainable green cell factories …
Article scientifique
In silico analysis of promoter regions to identify regulatory elements in TetR family transcriptional regulatory genes of Mycobacterium colombiense CECT 3035
BACKGROUND: Mycobacterium colombiense is an acid-fast, non-motile, rod-shaped mycobacterium confirmed to cause respiratory disease and disseminated infection in immune-compromised patients, …
Article scientifique
Omega-9 fatty acids: potential roles in inflammation and cancer management
BACKGROUND: Omega-9 fatty acids represent one of the main mono-unsaturated fatty acids (MUFA) found in plant and animal sources. They …
Erratum
Correction to: Livin/BIRC7 gene expression as a possible diagnostic biomarker for endometrial hyperplasia and carcinoma
Article scientifique
Edema in childhood nephrotic syndrome: possible genes–hormones interplay
BACKGROUND: The role of atrial natriuretic peptide (ANP) in edema formation in idiopathic nephrotic syndrome (INS) was studied before with …