66 publication(s) trouvée(s)
Article scientifique
Culturally adapted hypocaloric diet improves hepatic steatosis, inflammatory and oxidative biomarkers in Egyptian MASLD patients: a single-arm interventional study
BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a growing public health challenge in Egypt, driven by westernized dietary patterns, …
Article scientifique
Machine learning based identification potential feature genes for prediction of drug efficacy in nonalcoholic steatohepatitis animal model
BACKGROUND: Nonalcoholic Steatohepatitis (NASH) results from complex liver conditions involving metabolic, inflammatory, and fibrogenic processes. Despite its burden, there has …
Article scientifique
Association between biomarkers of inflammation and dyslipidemia in drug resistant tuberculosis in Uganda
BACKGROUND: Active tuberculosis (TB) significantly increases the risk of cardiovascular disease, but the underlying mechanisms remain unclear. This study aimed …
Article scientifique
Dyslipidemia: prevalence and association with precancerous and cancerous lesions of the cervix; a pilot study
BACKGROUND: In Sub-Saharan Africa, the prevalence of dyslipidemia is on the rise, with studies showing dyslipidemia as a contributing factor …
Article scientifique
Oxidized dietary lipids induce vascular inflammation and atherogenesis in post-menopausal rats: estradiol and selected antihyperlipidemic drugs restore vascular health in vivo
BACKGROUND: Thermoxidation of edible oil through deep fat frying results in the generation of several oxidized products that promote lipid …
Article scientifique
Comparative serum lipid and immunohematological values among adult pulmonary tuberculosis and tuberculosis lymphadenitis cases and their association with sputum bacilli load and time to culture positivity in Northwestern Ethiopia
BACKGROUND: The serum lipid and immunohematological values of tuberculosis lymphadenitis (TBLN) patients is poorly documented relative to pulmonary tuberculosis (PTB) …
Article scientifique
Lipoprotein subfraction patterns throughout gestation in The Gambia: changes in subfraction composition and their relationships with infant birth weights
BACKGROUND: Lipoprotein subfraction concentrations have been shown to change as gestation progresses in resource-rich settings. The objective of the current …
Article scientifique
Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation
BACKGROUND: Keloid formation following trauma or surgery is common among darkly pigmented individuals. Since lipoprotein(a) [Lp(a)] has been postulated to …
Article scientifique
Anthracycline-induced cardiotoxicity: targeting high-density lipoproteins to limit the damage?
Doxorubicin (DOX) is an anthracycline antibiotic frequently used against a wide range of cancers, including breast cancer. Although the drug …
Article scientifique
RNA-based therapy in the management of lipid disorders: a review
This review focuses on antisense oligonucleotides and small interfering ribonucleic acid therapies approved or under development for the management of …
Article scientifique
Lipid droplets and the transcriptome of Mycobacterium tuberculosis from direct sputa: a literature review
Mycobacterium tuberculosis (Mtb), the main etiology of tuberculosis (TB), is predominantly an intracellular pathogen that has caused infection, disease and …
Article scientifique
Cell surface sphingomyelin: key role in cancer initiation, progression, and immune evasion
Cell surface biochemical changes, notably excessive increase in outer leaflet sphingomyelin (SM) content, are important in cancer initiation, growth, and …
Article scientifique
Co-administration of HAART and antikoch triggers cardiometabolic dysfunction through an oxidative stress-mediated pathway
BACKGROUND: Antikoch and highly active anti-retroviral therapy are effective drugs in the management of tuberculosis and Human Immunodeficiency Virus, respectively. …
Article scientifique
Management strategy and novel ophthalmological findings in neonatal severe hypertriglyceridemia: a case report and literature review
BACKGROUND: Neonatal severe hypertriglyceridemia is rarely reported in the literature and there is no consensus for hypertriglyceridemia management at this …
Article scientifique
The impact of reactive oxygen species in the development of cardiometabolic disorders: a review
Oxidative stress, an alteration in the balance between reactive oxygen species (ROS) generation and antioxidant buffering capacity, has been implicated …
Article scientifique
Associations of linoleic acid with markers of glucose metabolism and liver function in South African adults
BACKGROUND: The relation between dietary and circulating linoleic acid (18:2 n-6, LA), glucose metabolism and liver function is not yet …
Article scientifique
Dietary fat quantity and quality in relation to general and abdominal obesity in women: a cross-sectional study from Ghana
BACKGROUND: Although relationships between obesity and total fat and fat types have been widely examined, the associations between the relative …
Article scientifique
Caspase-1 as a regulatory molecule of lipid metabolism
Caspase-1 is an evolutionarily conserved inflammatory mediated enzyme that cleaves and activates inflammatory cytokines. It can be activated through the …
Article scientifique
Leptin and psychiatric illnesses: does leptin play a role in antipsychotic-induced weight gain?
Antipsychotic-induced weight gain is the most prevalent somatic adverse event occurring in patients treated by antipsychotics, especially atypical antipsychotics. It …
Article scientifique
Leptin, resistin and visfatin as useful predictors of gestational diabetes mellitus
BACKGROUND: Lipids and adipokines including leptin, resistin and visfatin play various roles in the pathophysiology of Gestational Diabetes Mellitus (GDM). …
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