1722 publication(s) trouvée(s)
Article scientifique
Identification of factors associated with residual malaria transmission using school-based serological surveys in settings pursuing elimination
BACKGROUND: Targeted research on residual malaria transmission is important to improve strategies in settings pursuing elimination, where transmission reductions prove …
Article scientifique
An experimental hut study evaluating the impact of pyrethroid-only and PBO nets alone and in combination with pirimiphos-methyl-based IRS in Ethiopia
BACKGROUND: Pyrethroid resistance observed in populations of malaria vectors is widespread in Ethiopia and could potentially compromise the effectiveness of …
Article scientifique
Costs of treating childhood malaria, diarrhoea and pneumonia in rural Mozambique and Uganda
BACKGROUND: Globally, nearly half of all deaths among children under the age of 5 years can be attributed to malaria, …
Article scientifique
Molecular characterization and genotype distribution of thioester-containing protein 1 gene in Anopheles gambiae mosquitoes in western Kenya
Abstract Background Evolutionary pressures lead to the selection of efficient malaria vectors either resistant or susceptible to Plasmodium parasites. These …
Article scientifique
Field performance of Plasmodium falciparum lactate dehydrogenase rapid diagnostic tests during a large histidine-rich protein 2 deletion survey in Ethiopia
BACKGROUND: Malaria rapid diagnostic tests (RDTs) have expanded diagnostic service to remote endemic communities in Ethiopia, where 70% of malaria …
Article scientifique
Assessing the relationship between gravidity and placental malaria among pregnant women in a high transmission area in Ghana
BACKGROUND: Malaria infection during pregnancy can cause significant morbidity and mortality to a pregnant woman, her fetus and newborn. In …
Article scientifique
The in-vivo dynamics of Plasmodium falciparum HRP2: implications for the use of rapid diagnostic tests in malaria elimination
BACKGROUND: Rapid diagnostic tests (RDTs) that rely on the detection of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) have become key …
Article scientifique
Vivax malaria in Duffy-negative patients shows invariably low asexual parasitaemia: implication towards malaria control in Ethiopia
BACKGROUND: The increase in detections of Plasmodium vivax infection in Duffy-negative individuals in Africa has challenged the dogma establishing the …
Article scientifique
Population knowledge, attitudes and practices towards malaria prevention in the locality of Makenene, Centre-Cameroon
BACKGROUND: To contribute to the mission of the National Malaria Control Programme (NMCP) and guide future interventions in Cameroon in …
Article scientifique
Annual distributions of insecticide-treated nets to schoolchildren and other key populations to maintain higher ITN access than with mass campaigns: a modelling study for mainland Tanzania
BACKGROUND: Since 2013, the National Malaria Control Programme in mainland Tanzania has deployed annual distributions of insecticide-treated nets (ITNs) through …
Article scientifique
Evaluation of anti-malarial potency of new pyrazole-hydrazine coupled to Schiff base derivatives
BACKGROUND: The search for pharmacologically effective agents among molecules bearing multiple functionalities is commonly practiced. In continuation of the search …
Article scientifique
Quinine plus clindamycin vs artemether-lumefantrine for treatment of uncomplicated falciparum malaria in western Kenya
Article scientifique
Multiple Plasmodium falciparum drug resistance polymorphisms identified in a pregnant woman with severe malaria and a concomitant spontaneous abortion in Cross River, Nigeria, West Africa
BACKGROUND: The development of resistance by Plasmodium falciparum to anti-malarial drugs impedes any benefits of the drug. In addition, absence …
Article scientifique
Implementing OECD GLP principles for the evaluation of novel vector control tools: a case study with two novel LLINs, SafeNet® and SafeNet NF®
Abstract Background To sustain high universal Long-Lasting Insecticidal Nets (LLINs) coverage, affordable nets that provide equivalent or better protection than …
Article scientifique
Expression and copper binding characteristics of Plasmodium falciparum cytochrome c oxidase assembly factor 11, Cox11
Abstract Background Copper is an essential metal for living organisms as a catalytic co-factor for important enzymes, like cytochrome c …
Article scientifique
The private sector market for malaria rapid diagnostic tests in Nigeria: results of the 2018 market survey
BACKGROUND: To avoid misuse of anti-malarials, correct diagnosis of fever prior to drug prescription is essential. Presumptive treatment in the …
Article scientifique
A cluster randomized trial of delivery of intermittent preventive treatment of malaria in pregnancy at the community level in Malawi
BACKGROUND: Malaria in pregnancy doubles the risk of low birthweight; up to 11% of all neonatal deaths in sub-Saharan Africa …
Article scientifique
Cattle-related risk factors for malaria in southwest Ethiopia: a cross-sectional study
BACKGROUND: Despite the low to moderate intensity of malaria transmission present in Ethiopia, malaria is still a leading public health …
Article scientifique
Making data map-worthy—enhancing routine malaria data to support surveillance and mapping of Plasmodium falciparum anti-malarial resistance in a pre-elimination sub-Saharan African setting: a molecular and spatiotemporal epidemiology study
BACKGROUND: Independent emergence and spread of artemisinin-resistant Plasmodium falciparum malaria have recently been confirmed in Africa, with molecular markers associated …
Article scientifique
Cellular and antibody response in GMZ2-vaccinated Gabonese volunteers in a controlled human malaria infection trial
BACKGROUND: Antibody and cellular memory responses following vaccination are important measures of immunogenicity. These immune markers were quantified in the …