1722 publication(s) trouvée(s)
Article scientifique
Putative pleiotropic effects of the knockdown resistance (L1014F) allele on the life-history traits of Anopheles gambiae
BACKGROUND: (L1014F) is the most common. However, little knowledge is available on its effects on mosquito life-history traits. The fitness …
Article scientifique
Community knowledge, perceptions, and practices regarding malaria and its control in Jabi Tehnan district, Amhara Region, Northwest Ethiopia
BACKGROUND: Use of long-lasting insecticidal nets (LLINs), indoor residual spraying (IRS), community-based malaria education, prompt diagnosis and treatment are key …
Article scientifique
Genetic markers associated with insecticide resistance and resting behaviour in Anopheles gambiae mosquitoes in selected sites in Kenya
Abstract Background Molecular diagnostic tools have been incorporated in insecticide resistance monitoring programmes to identify underlying genetic basis of resistance …
Article scientifique
Investigating molecular mechanisms of insecticide resistance in the Eastern Democratic Republic of the Congo
BACKGROUND: Malaria vector control in the Democratic Republic of the Congo is plagued by several major challenges, including inadequate infrastructure, …
Article scientifique
Determinants of malaria testing at health facilities: the case of Uganda
BACKGROUND: The World Health Organization (WHO) recommends prompt malaria diagnosis with either microscopy or malaria rapid diagnostic tests (RDTs) and …
Article scientifique
Guiding placement of health facilities using multiple malaria criteria and an interactive tool
BACKGROUND: Access to healthcare is important in controlling malaria burden and, as a result, distance or travel time to health …
Article scientifique
The effect of long-lasting insecticidal nets (LLINs) physical integrity on utilization
BACKGROUND: In Ethiopia, despite improvements in coverage and access, utilization of long-lasting insecticidal nets (LLINs) remains a challenge. Different household-level …
Article scientifique
Insecticidal effect of ethnobotanical plant extracts against Anopheles arabiensis under laboratory conditions
BACKGROUND: The emergence and spread of resistant strains of malaria vectors to chemical insecticides are becoming major problems for malaria …
Article scientifique
Temporal evolution of the resistance genotypes of Plasmodium falciparum in isolates from Equatorial Guinea during 20 years (1999 to 2019)
BACKGROUND: Malaria is one of the deadliest diseases in the world, particularly in Africa. As such, resistance to anti-malarial drugs …
Article scientifique
Hyper-prevalence of submicroscopic Plasmodium falciparum infections in a rural area of western Kenya with declining malaria cases
BACKGROUND: The gold standard for diagnosing Plasmodium falciparum infection is microscopic examination of Giemsa-stained peripheral blood smears. The effectiveness of …
Article scientifique
Citizen science for monitoring the spatial and temporal dynamics of malaria vectors in relation to environmental risk factors in Ruhuha, Rwanda
BACKGROUND: As part of malaria prevention and control efforts, the distribution and density of malaria mosquitoes requires continuous monitoring. Resources …
Article scientifique
Risk factors associated with malaria infection identified through reactive case detection in Zanzibar, 2012–2019
BACKGROUND: Over the past two decades, Zanzibar substantially reduced malaria burden. As malaria decreases, sustainable improvements in control interventions may …
Article scientifique
Seven-year kinetics of RTS, S/AS01-induced anti-CSP antibodies in young Kenyan children
BACKGROUND: RTS,S/AS01, the leading malaria vaccine has been recommended by the WHO for widespread immunization of children at risk. RTS,S/AS01-induced …
Article scientifique
Hepatic safety and tolerability of cipargamin (KAE609), in adult patients with Plasmodium falciparum malaria: a randomized, phase II, controlled, dose-escalation trial in sub-Saharan Africa
BACKGROUND: The novel anti-malarial cipargamin (KAE609) has potent, rapid activity against Plasmodium falciparum. Transient asymptomatic liver function test elevations were …
Article scientifique
Impact of COVID-19 on routine malaria indicators in rural Uganda: an interrupted time series analysis
BACKGROUND: In March 2020, the government of Uganda implemented a strict lockdown policy in response to the COVID-19 pandemic. Interrupted …
Article scientifique
Prevalence of potential mediators of artemisinin resistance in African isolates of Plasmodium falciparum
Abstract Background The devastating public health impact of malaria has prompted the need for effective interventions. Malaria control gained traction …
Article scientifique
Efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria and prevalence of molecular markers associated with artemisinin and partner drug resistance in Uganda
BACKGROUND: In Uganda, artemether-lumefantrine (AL) is first-line therapy and dihydroartemisinin-piperaquine (DP) second-line therapy for the treatment of uncomplicated malaria. This …
Article scientifique
Acceptability of peer learning and education approach on malaria prevention (PLEA-malaria) through primary schools communities in rural Ethiopia: peer educators’ perspectives
BACKGROUND: Evidence on peer educators' experiences of implementing the school-based educational interventions on malaria prevention would be used as inputs …
Article scientifique
Longitudinal analysis of FcRL5 expression and clonal relationships among classical and atypical memory B cells following malaria
Abstract Background Chronic and frequently recurring infectious diseases, such as malaria, are associated with expanded populations of atypical memory B …
Article scientifique
Efficacy of artesunate-amodiaquine and artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria in Madagascar, 2018
BACKGROUND: Since 2005, artemisinin-based combination therapy (ACT) has been recommended to treat uncomplicated falciparum malaria in Madagascar. Artesunate-amodiaquine (ASAQ) and …