1722 publication(s) trouvée(s)
Article scientifique
Prevalence and distribution of G6PD deficiency: implication for the use of primaquine in malaria treatment in Ethiopia
BACKGROUND: G6PD enzyme deficiency is a common enzymatic X-linked disorder. Deficiency of the G6PD enzyme can cause free radical-mediated oxidative …
Article scientifique
Ultrasensitive loop mediated isothermal amplification (US-LAMP) to detect malaria for elimination
BACKGROUND: Malaria elimination requires diagnostic methods able to detect parasite levels well below what is currently possible with microscopy and …
Article scientifique
Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of chloroquine
BACKGROUND: A reversal of chloroquine (CQ) resistance following a period of withdrawal has raised the possibility of its re-introduction. This …
Article scientifique
Detection of malaria parasites in dried human blood spots using mid-infrared spectroscopy and logistic regression analysis
BACKGROUND: Epidemiological surveys of malaria currently rely on microscopy, polymerase chain reaction assays (PCR) or rapid diagnostic test kits for …
Article scientifique
Effect of LongRange™ eprinomectin on Anopheles arabiensis by feeding on calves treated with the drug
BACKGROUND: Misuse of long-lasting insecticidal nets together with resistance of vectors to most of the insecticides for indoor residual spraying …
Article scientifique
Differential expression of var subgroups and PfSir2a genes in afebrile Plasmodium falciparum malaria: a matched case–control study
BACKGROUND: Poor knowledge on the afebrile Plasmodium falciparum biology limits elimination approaches to target asymptomatic malaria. Therefore, the association of …
Article scientifique
Targeted Next Generation Sequencing for malaria research in Africa: current status and outlook
Targeted Next Generation Sequencing (TNGS) is an efficient and economical Next Generation Sequencing (NGS) platform and the preferred choice when …
Article scientifique
Intermittent preventive treatment of malaria delivered to primary schoolchildren provided effective individual protection in Jinja, Uganda: secondary outcomes of a cluster-randomized trial (START-IPT)
BACKGROUND: Intermittent preventive treatment (IPT) of malaria is recommended as policy for certain high-risk populations, but not currently for schoolchildren. …
Article scientifique
Getting ready for integrated vector management for improved disease prevention in Zimbabwe: a focus on key policy issues to consider
BACKGROUND: This paper outlines Zimbabwe's potential readiness in harnessing integrated vector management (IVM) strategy for enhanced control of vector-borne diseases. …
Article scientifique
Rare mutations in Pfmdr1 gene of Plasmodium falciparum detected in clinical isolates from patients treated with anti-malarial drug in Nigeria
BACKGROUND: Plasmodium falciparum, the deadliest causative agent of malaria, has high prevalence in Nigeria. Drug resistance causing failure of previously …
Article scientifique
Plasmodium vivax cerebral malaria in an adult patient in Sudan
BACKGROUND: Plasmodium vivax infection is rising in sub-Saharan Africa, where Plasmodium falciparum is responsible for more than 90% of malaria …
Article scientifique
Net age, but not integrity, may be associated with decreased protection against Plasmodium falciparum infection in southern Malawi
BACKGROUND: Distribution campaigns for insecticide-treated nets (ITN) have increased the use of ITNs in Malawi, but malaria prevalence remains high …
Article scientifique
Deployment and utilization of next-generation sequencing of Plasmodium falciparum to guide anti-malarial drug policy decisions in sub-Saharan Africa: opportunities and challenges
Parasite resistance against anti-malarial drugs is a major threat to the ongoing malaria control and elimination strategies. This is especially …
Article scientifique
Impact of Plasmodium falciparum malaria and intermittent preventive treatment of malaria in pregnancy on the risk of malaria in infants: a systematic review
BACKGROUND: Studies of the association between malaria in pregnancy (MiP) and malaria during infancy have provided mixed results. A systematic …
Article scientifique
Malaria around large dams in Africa: effect of environmental and transmission endemicity factors
BACKGROUND: The impact of large dams on malaria has received widespread attention. However, understanding how dam topography and transmission endemicity …
Article scientifique
Poverty and food security: drivers of insecticide-treated mosquito net misuse in Malawi
BACKGROUND: Over the past decade, food insecurity, connected to erratic rains and reduced agricultural outputs, has plagued Malawi. Many households …
Article scientifique
Eave ribbons treated with transfluthrin can protect both users and non-users against malaria vectors
BACKGROUND: Eave ribbons treated with spatial repellents effectively prevent human exposure to outdoor-biting and indoor-biting malaria mosquitoes, and could constitute …
Article scientifique
Extent of inappropriate prescription of artemisinin and anti-malarial injections to febrile outpatients, a cross-sectional analytic survey in the Greater Accra region, Ghana
BACKGROUND: Febrile children seen in malaria hypo-endemic settings, such as the Greater Accra region (GAR) of Ghana are more likely …
Article scientifique
Reduction of malaria vector mosquitoes in a large-scale intervention trial in rural Burkina Faso using Bti based larval source management
BACKGROUND: Malaria remains one of the most important causes of morbidity and death in sub-Saharan Africa. Along with early diagnosis …
Article scientifique
Applying next-generation sequencing to track falciparum malaria in sub-Saharan Africa
Next-generation sequencing (NGS) technologies are increasingly being used to address a diverse range of biological and epidemiological questions. The current …