1722 publication(s) trouvée(s)
Article scientifique
Measuring malaria diagnosis and treatment coverage in population-based surveys: a recall validation study in Mali among caregivers of febrile children under 5 years
BACKGROUND: Nationally-representative household surveys are the standard approach to monitor access to and treatment with artemisinin-based combination therapy (ACT) among …
Article scientifique
MiRNA-146a polymorphism increases the odds of malaria in pregnancy
BACKGROUND: Plasmodium falciparum infection during pregnancy is a major cause of poor maternal health, adverse foetal outcome and infant mortality …
Article scientifique
Development of an agent-based model to assess the impact of substandard and falsified anti-malarials: Uganda case study
BACKGROUND: Global efforts to address the burden of malaria have stagnated in recent years with malaria cases beginning to rise. …
Article scientifique
The impact of early life exposure to Plasmodium falciparum on the development of naturally acquired immunity to malaria in young Malawian children
BACKGROUND: Antibodies targeting malaria blood-stage antigens are important targets of naturally acquired immunity, and may act as valuable biomarkers of …
Article scientifique
Swarms of the malaria vector Anopheles funestus in Tanzania
BACKGROUND: Anopheles funestus mosquitoes currently contribute more than 85% of ongoing malaria transmission events in south-eastern Tanzania, even though they …
Article scientifique
Molecular monitoring of the diversity of human pathogenic malaria species in blood donations on Bioko Island, Equatorial Guinea
BACKGROUND: Malaria can be transmitted by blood transfusion from human to human and it is responsible for the majority of …
Article scientifique
Community knowledge and acceptance of indoor residual spraying for malaria prevention in Mozambique: a qualitative study
Malaria control remains a leading health challenge in Mozambique. Indoor residual spraying (IRS) is an effective strategy to control malaria …
Article scientifique
Measuring and characterizing night time human behaviour as it relates to residual malaria transmission in sub-Saharan Africa: a review of the published literature
BACKGROUND: Malaria cases and deaths decreased dramatically in recent years, largely due to effective vector control interventions. Persistence of transmission …
Article scientifique
Mitochondrial gene sequence variants in children with severe malaria anaemia with or without lactic acidosis: a case control study
BACKGROUND: Evolutionary pressure by Plasmodium falciparum malaria is known to have favoured a large number of human gene adaptations, but …
Article scientifique
Treatments used for malaria in young Ethiopian children: a retrospective study
BACKGROUND: In Ethiopia, medicinal plants have been used to treat different diseases, including malaria, for many centuries. People living in …
Article scientifique
Interplay between Plasmodium falciparum haemozoin and l-arginine: implication for nitric oxide production
BACKGROUND: Plasmodium falciparum haemozoin, a detoxification product of digested haemoglobin from infected erythrocytes, is released into the bloodstream upon schizont …
Article scientifique
Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools
BACKGROUND: Most epidemiological studies on the interplay between iron deficiency and malaria risk classify individuals as iron-deficient or iron-replete based …
Article scientifique
Accuracy of One Step malaria rapid diagnostic test (RDT) in detecting Plasmodium falciparum placental malaria infection in women living in Yaoundé, Cameroon
BACKGROUND: Plasmodium falciparum infected erythrocytes sequestering in placental tissue release Plasmodium lactate dehydrogenase (pLDH) and histidine-rich protein-II (HRP-II). These proteins …
Article scientifique
Diagnostic capacity, and predictive values of rapid diagnostic tests for accurate diagnosis of Plasmodium falciparum in febrile children in Asante-Akim, Ghana
BACKGROUND: This study seeks to compare the performance of HRP2 (First Response) and pLDH/HRP2 (Combo) RDTs for falciparum malaria against …
Article scientifique
Caregiver responses and association with delayed care-seeking in children with uncomplicated and severe malaria
BACKGROUND: Gaps remain in understanding the role of caregiver responses on time to seek appropriate care. The objective of this …
Article scientifique
Diagnostic performance of salivary urea nitrogen dipstick to detect and monitor acute kidney disease in patients with malaria
BACKGROUND: Acute kidney injury (AKI) is a common complication of malaria. In low resource settings, a lack of diagnostic tools …
Article scientifique
Malaria case investigation with reactive focal testing and treatment: operational feasibility and lessons learned from low and moderate transmission areas in Amhara Region, Ethiopia
BACKGROUND: When malaria transmission is very low, investigation of passively detected malaria cases and reactive focal testing and treatment (FTAT) …
Article scientifique
Heterogeneous distribution of k13 mutations in Plasmodium falciparum in Laos
BACKGROUND: The emergence and transnational spread of artemisinin resistance in Plasmodium falciparum in the Greater Mekong Sub-region (GMS) is a …
Article scientifique
Characterization of Plasmodium falciparum structure in Nigeria with malaria SNPs barcode
BACKGROUND: Plasmodium falciparum malaria remains a major health challenge in Nigeria despite the global decline of its incidence and mortality …
Article scientifique
Subpatent malaria in a low transmission African setting: a cross-sectional study using rapid diagnostic testing (RDT) and loop-mediated isothermal amplification (LAMP) from Zambezi region, Namibia
BACKGROUND: Subpatent malaria infections, or low-density infections below the detection threshold of microscopy or standard rapid diagnostic testing (RDT), can …