1722 publication(s) trouvée(s)
Article scientifique
Insecticide resistance in Anopheles gambiae from the northern Democratic Republic of Congo, with extreme knockdown resistance (kdr) mutation frequencies revealed by a new diagnostic assay
BACKGROUND: Mutations in the voltage-gated sodium channel at codon 1014 confer knock-down resistance (kdr) to pyrethroids in a wide range …
Article scientifique
Early treatment-seeking behaviour for malaria in febrile patients in northwest Ethiopia
BACKGROUND: As malaria is among the leading public health problems globally, early diagnosis and treatment of cases is one of …
Article scientifique
A multiplex assay for the sensitive detection and quantification of male and female Plasmodium falciparum gametocytes
The transmission of malaria to mosquitoes depends on the presence of gametocytes that circulate in the peripheral blood of infected …
Article scientifique
LLIN Evaluation in Uganda Project (LLINEUP): factors associated with ownership and use of long-lasting insecticidal nets in Uganda: a cross-sectional survey of 48 districts
BACKGROUND: Long-lasting insecticidal nets (LLINs) are a key malaria control intervention. To investigate factors associated with ownership and use of …
Article scientifique
Dry season occurrence of Anopheles mosquitoes and implications in Jabi Tehnan District, West Gojjam Zone, Ethiopia
BACKGROUND: Generating evidence on the dry season occurrence of the larval and adult stages of Anopheles mosquitoes helps to design …
Article scientifique
High purity high yield tandem B and T helper cell isolation for qRT-PCR analysis suitable for basically equipped laboratories
BACKGROUND: Malaria is still a major health problem in sub-Saharan Africa and south-east Asia, but research on malaria in low-income …
Article scientifique
Can malaria rapid diagnostic tests by drug sellers under field conditions classify children 5 years old or less with or without Plasmodium falciparum malaria? Comparison with nested PCR analysis
BACKGROUND: Malaria rapid diagnostic tests (RDTs) available as dipsticks or strips, are simple to perform, easily interpretable and do not …
Article scientifique
Household costs and time to treatment for children with severe febrile illness in rural Burkina Faso: the role of rectal artesunate
BACKGROUND: Community health workers (CHWs) were trained to identify children with malaria who could not take oral medication, treat them …
Article scientifique
Assessment of parasite clearance following treatment of severe malaria with intravenous artesunate in Ugandan children enrolled in a randomized controlled clinical trial
BACKGROUND: Malaria control largely depends on availability of highly efficacious drugs, however, over the years, has been threatened by emergence …
Article scientifique
Dynamics of Plasmodium falciparum gametocyte carriage in pregnant women under intermittent preventive treatment with sulfadoxine–pyrimethamine in Benin
BACKGROUND: In sub-Saharan Africa, malaria is a major cause of morbidity and mortality, in particular in children and pregnant women. …
Article scientifique
“I feel so bad but have nothing to do.” Exploring Ugandan caregivers’ experiences of parenting a child with severe malaria and subsequent repeated uncomplicated malaria
BACKGROUND: Severe malaria in children is often associated with long-term behavioural and cognitive problems. A sizeable minority of children go …
Article scientifique
Glucose-6-phosphate dehydrogenase activity measured by spectrophotometry and associated genetic variants from the Oromiya zone, Ethiopia
BACKGROUND: The study aimed to gain first data on the prevalence of G6PD enzyme deficiency measured by spectrophotometry and associated …
Article scientifique
‘For the poor, sleep is leisure’: understanding perceptions, barriers and motivators to mosquito net care and repair in southern Tanzania
BACKGROUND: The rate of physical deterioration of long-lasting insecticidal nets (LLINs) varies by household practices, net brand and environment. One …
Article scientifique
Completion of community health worker initiated patient referrals in integrated community case management in rural Uganda
BACKGROUND: Uganda has sought to address leading causes of childhood mortality: malaria, pneumonia and diarrhoea, through integrated community case management …
Article scientifique
Screening and field performance of powder-formulated insecticides on eave tube inserts against pyrethroid resistant Anopheles gambiae s.l.: an investigation into ‘actives’ prior to a randomized controlled trial in Côte d’Ivoire
BACKGROUND: The widespread emergence of insecticide resistance in African malaria vectors remains one of the main challenges facing control programmes. …
Article scientifique
Prevalence of Plasmodium falciparum infection among pregnant women at first antenatal visit in post-Ebola Monrovia, Liberia
BACKGROUND: Disruption of malaria control strategies during the West African 2014-2016 Ebola epidemic led to an increase in malaria-attributable mortality. …
Article scientifique
Knowledge, motivation, self-efficacy, and their association with insecticidal net use among pregnant women in a secondary health centre in Maiduguri, Nigeria
BACKGROUND: Despite the high prevalence of malaria among pregnant women and its associated complications, the level of compliance with insecticide-treated …
Article scientifique
Field assessment of potential sugar feeding stations for disseminating bacteria in a paratransgenic approach to control malaria
BACKGROUND: Using bacteria to express and deliver anti-parasite molecules in mosquitoes is among the list of genetic tools to control …
Article scientifique
Another challenge in malaria elimination efforts: the increase of malaria among adults after the implementation of long-lasting insecticide-treated nets (LLINs) in Dielmo, Senegal
The widespread use of artemisinin-based combination therapy (ACT) and long-lasting insecticide-treated nets (LLINs) has led to an impressive decrease of …
Article scientifique
Selective sweeps and genetic lineages of Plasmodium falciparum multi-drug resistance (pfmdr1) gene in Kenya
BACKGROUND: There are concerns that resistance to artemisinin-based combination therapy might emerge in Kenya and sub-Saharan Africa (SSA) in the …