1722 publication(s) trouvée(s)
Article scientifique
Efficacy of artesunate–amodiaquine, dihydroartemisinin–piperaquine and artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Maradi, Niger
BACKGROUND: Malaria endemic countries need to assess efficacy of anti-malarial treatments on a regular basis. Moreover, resistance to artemisinin that …
Article scientifique
The importance of morphological identification of African anopheline mosquitoes (Diptera: Culicidae) for malaria control programmes
BACKGROUND: The correct identification of disease vectors is the first step towards implementing an effective control programme. Traditionally, for malaria …
Article scientifique
Effect of individual and community-level bed net usage on malaria prevalence among under-fives in the Democratic Republic of Congo
BACKGROUND: Understanding the contribution of community-level long-lasting, insecticidal net (LLIN) coverage to malaria control is critical to planning and assessing …
Article scientifique
Extensive diversity in the allelic frequency of Plasmodium falciparum merozoite surface proteins and glutamate-rich protein in rural and urban settings of southwestern Nigeria
BACKGROUND: Nigeria carries a high burden of malaria which makes continuous surveillance for current information on genetic diversity imperative. In …
Article scientifique
Demand-related factors influencing caregivers’ awareness of malaria tests and health workers’ testing practices, in Makarfi, Nigeria
BACKGROUND: Despite the World Health Organization's recommendation of malaria test-treat strategy, which is the treatment of parasitological confirmed malaria cases …
Article scientifique
When it just won’t go away: oral artemisinin monotherapy in Nigeria, threatening lives, threatening progress
Oral artemisinin monotherapy (AMT), an important contributor to multi-drug resistant malaria, has been banned in Nigeria. While oral AMT has …
Article scientifique
In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine
Discovery of novel gametocytocidal molecules is a major pharmacological strategy in the elimination and eradication of malaria. The high patronage …
Article scientifique
Both inflammatory and regulatory cytokine responses to malaria are blunted with increasing age in highly exposed children
BACKGROUND: Young children are at greatest risk for malaria-associated morbidity and mortality. The immune response of young children differs in …
Article scientifique
Why some sites are responding better to anti-malarial interventions? A case study from western Kenya
BACKGROUND: In sub-Saharan Africa, malaria interventions over the last decades have been successful in reducing both mortality and morbidity. In …
Article scientifique
The malaria testing and treatment landscape in Kenya: results from a nationally representative survey among the public and private sector in 2016
BACKGROUND: Since 2004, Kenya's national malaria treatment guidelines have stipulated artemisinin-based combination therapy (ACT) as first-line treatment for uncomplicated malaria, …
Article scientifique
Plasmodium falciparum variant erythrocyte surface antigens: a pilot study of antibody acquisition in recurrent natural infections
BACKGROUND: During intra-erythrocytic replication Plasmodium falciparum escapes the human host immune system by switching expression of variant surface antigens (VSA). …
Article scientifique
Temporal variation in confirmed diagnosis of fever-related malarial cases among children under-5 years by community health workers and in health facilities between years 2013 and 2015 in Siaya County, Kenya
BACKGROUND: Malaria case management continues to experience dynamic changes. Building community capacity is instrumental in both prevention and treatment of …
Article scientifique
Age-specific Plasmodium parasite profile in pre and post ITN intervention period at a highland site in western Kenya
BACKGROUND: Monitoring and evaluation of entomological, parasitological and clinical data is an important component of malaria control as it is …
Article scientifique
Variation in the immune responses against Plasmodium falciparum merozoite surface protein-1 and apical membrane antigen-1 in children residing in the different epidemiological strata of malaria in Cameroon
Studies to assess the immune responses against malaria in Cameroonian children are limited. The purpose of this study was to …
Article scientifique
Shifting the burden or expanding access to care? Assessing malaria trends following scale-up of community health worker malaria case management and reactive case detection
BACKGROUND: Malaria is a significant burden to health systems and is responsible for a large proportion of outpatient cases at …
Article scientifique
Malaria prevalence metrics in low- and middle-income countries: an assessment of precision in nationally-representative surveys
BACKGROUND: One pillar to monitoring progress towards the Sustainable Development Goals is the investment in high quality data to strengthen …
Article scientifique
Evaluation of the Deki Reader™, an automated RDT reader and data management device, in a household survey setting in low malaria endemic southwestern Uganda
BACKGROUND: Early diagnosis of suspected malaria cases with a rapid diagnostic test (RDT) has been shown to be an effective …
Article scientifique
Host age and Plasmodium falciparum multiclonality are associated with gametocyte prevalence: a 1-year prospective cohort study
BACKGROUND: Since Plasmodium falciparum transmission relies exclusively on sexual-stage parasites, several malaria control strategies aim to disrupt this step of …
Article scientifique
Determination of the residual efficacy of carbamate and organophosphate insecticides used for indoor residual spraying for malaria control in Ethiopia
Indoor residual spraying is one of the key vector control interventions for malaria control in Ethiopia. As malaria transmission is …
Article scientifique
Malaria early warning tool: linking inter-annual climate and malaria variability in northern Guadalcanal, Solomon Islands
BACKGROUND: Malaria control remains a significant challenge in the Solomon Islands. Despite progress made by local malaria control agencies over …