397 publication(s) trouvée(s)
Article scientifique
Risk-stratification of febrile African children at risk of sepsis using sTREM-1 as basis for a rapid triage test
Identifying febrile children at risk of sepsis in low-resource settings can improve survival, but recognition triage tools are lacking. Here …
Article scientifique
Model-based assessment of Chikungunya and O’nyong-nyong virus circulation in Mali in a serological cross-reactivity context
Serological surveys are essential to quantify immunity in a population but serological cross-reactivity often impairs estimates of the seroprevalence. Here, …
Article scientifique
Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights
Understanding the molecular and phenotypic profile of colorectal cancer (CRC) in West Africa is vital to addressing the regions rising …
Article scientifique
Volcanic activity and hazard in the East African Rift Zone
Over the past two decades, multidisciplinary studies have unearthed a rich history of volcanic activity and unrest in the densely-populated …
Article scientifique
Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes
Black women across the African diaspora experience more aggressive breast cancer with higher mortality rates than white women of European …
Article scientifique
Quantifying previous SARS-CoV-2 infection through mixture modelling of antibody levels
As countries decide on vaccination strategies and how to ease movement restrictions, estimating the proportion of the population previously infected …
Article scientifique
Clinical outcomes and cost-effectiveness of COVID-19 vaccination in South Africa
Low- and middle-income countries are implementing COVID-19 vaccination strategies in light of varying vaccine efficacies and costs, supply shortages, and …
Article scientifique
SARS-CoV-2 antibody seroprevalence and associated risk factors in an urban district in Cameroon
The extent of SARS-CoV-2 circulation in many African countries remains unclear, underlining the need for antibody sero-surveys to assess the …
Article scientifique
Emergence and spread of SARS-CoV-2 lineage B.1.620 with variant of concern-like mutations and deletions
Distinct SARS-CoV-2 lineages, discovered through various genomic surveillance initiatives, have emerged during the pandemic following unprecedented reductions in worldwide human …
Article scientifique
Geographical drivers and climate-linked dynamics of Lassa fever in Nigeria
Lassa fever is a longstanding public health concern in West Africa. Recent molecular studies have confirmed the fundamental role of …
Article scientifique
The gut microbiome in konzo
Konzo, a distinct upper motor neuron disease associated with a cyanogenic diet and chronic malnutrition, predominately affects children and women …
Article scientifique
Modelling the persistence and control of Rift Valley fever virus in a spatially heterogeneous landscape
The persistence mechanisms of Rift Valley fever (RVF), a zoonotic arboviral haemorrhagic fever, at both local and broader geographical scales …
Article scientifique
Genomic sequencing of SARS-CoV-2 in Rwanda reveals the importance of incoming travelers on lineage diversity
COVID-19 transmission rates are often linked to locally circulating strains of SARS-CoV-2. Here we describe 203 SARS-CoV-2 whole genome sequences …
Article scientifique
Collaborative management of the Grand Ethiopian Renaissance Dam increases economic benefits and resilience
The landscape of water infrastructure in the Nile Basin is changing with the construction of the Grand Ethiopian Renaissance Dam. …
Article scientifique
Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya
Abstract Genomic surveillance of SARS-CoV-2 is important for understanding both the evolution and the patterns of local and global transmission. …
Article scientifique
The epidemiology of Plasmodium vivax among adults in the Democratic Republic of the Congo
Reports of P. vivax infections among Duffy-negative hosts have accumulated throughout sub-Saharan Africa. Despite this growing body of evidence, no …
Article scientifique
Plasmodium falciparum transcription in different clinical presentations of malaria associates with circulation time of infected erythrocytes
Following Plasmodium falciparum infection, individuals can remain asymptomatic, present with mild fever in uncomplicated malaria cases, or show one or …
Article scientifique
Distinct clinical and immunological profiles of patients with evidence of SARS-CoV-2 infection in sub-Saharan Africa
Although the COVID-19 pandemic has left no country untouched there has been limited research to understand clinical and immunological responses …
Article scientifique
Evidence of the interplay of genetics and culture in Ethiopia
The rich linguistic, ethnic and cultural diversity of Ethiopia provides an unprecedented opportunity to understand the level to which cultural …
Article scientifique
Two decades of neuroscience publication trends in Africa
Neuroscience research in Africa remains sparse. Devising new policies to boost Africa's neuroscience landscape is imperative, but these must be …