397 publication(s) trouvée(s)
Article scientifique
Risk of yellow fever virus transmission in the Asia-Pacific region
Historically endemic to Sub-Saharan Africa and South America, yellow fever is absent from the Asia-Pacific region. Yellow fever virus (YFV) …
Article scientifique
Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial
Young women in sub-Saharan Africa are disproportionally affected by HIV infection and unintended pregnancies. However, hormonal contraceptive (HC) use may …
Article scientifique
Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria
The mechanisms behind the ability of Plasmodium falciparum to evade host immune system are poorly understood and are a major …
Article scientifique
Pearl millet genomic vulnerability to climate change in West Africa highlights the need for regional collaboration
Climate change is already affecting agro-ecosystems and threatening food security by reducing crop productivity and increasing harvest uncertainty. Mobilizing crop …
Article scientifique
An integrated personal and population-based Egyptian genome reference
A small number of de novo assembled human genomes have been reported to date, and few have been complemented with …
Article scientifique
Livestock enclosures in drylands of Sub-Saharan Africa are overlooked hotspots of N2O emissions
Abstract Sub-Saharan Africa (SSA) is home to approximately ¼ of the global livestock population, which in the last 60 years …
Article scientifique
Yield reduction under climate warming varies among wheat cultivars in South Africa
Understanding extreme weather impacts on staple crops such as wheat is vital for creating adaptation strategies and increasing food security, …
Article scientifique
Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time
Recent outbreaks of viral hemorrhagic fevers (VHFs), including Ebola virus disease (EVD) and Lassa fever (LF), highlight the urgent need …
Erratum
Author Correction: Fossilized solidification fronts in the Bushveld Complex argue for liquid-dominated magmatic systems
An amendment to this paper has been published and can be accessed via a link at the top of the …
Article scientifique
Calcium isotopic ecology of Turkana Basin hominins
Abstract Diet is a major driver of hominin evolution, but most of the geochemical evidence relies on carbon isotopes (δ …
Article scientifique
Modelling the incremental benefit of introducing malaria screening strategies to antenatal care in Africa
Plasmodium falciparum in pregnancy is a major cause of adverse pregnancy outcomes. We combine performance estimates of standard rapid diagnostic …
Article scientifique
Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation
Genomic evolution, transmission and pathogenesis of Streptococcus pneumoniae, an opportunistic human-adapted pathogen, is driven principally by nasopharyngeal carriage. However, little …
Article scientifique
Long-term droughts may drive drier tropical forests towards increased functional, taxonomic and phylogenetic homogeneity
Tropical ecosystems adapted to high water availability may be highly impacted by climatic changes that increase soil and atmospheric moisture …
Article scientifique
Fossilized solidification fronts in the Bushveld Complex argue for liquid-dominated magmatic systems
Chemical differentiation of magma on Earth occurs through physical separation of liquids and crystals. The mechanisms of this separation still …
Article scientifique
Fossils from Mille-Logya, Afar, Ethiopia, elucidate the link between Pliocene environmental changes and Homo origins
Several hypotheses posit a link between the origin of Homo and climatic and environmental shifts between 3 and 2.5 Ma. …
Article scientifique
High residual carriage of vaccine-serotype Streptococcus pneumoniae after introduction of pneumococcal conjugate vaccine in Malawi
There are concerns that pneumococcal conjugate vaccines (PCVs) in sub-Saharan Africa sub-optimally interrupt Streptococcus pneumoniae vaccine-serotype (VT) carriage and transmission. …
Article scientifique
A microsporidian impairs Plasmodium falciparum transmission in Anopheles arabiensis mosquitoes
A possible malaria control approach involves the dissemination in mosquitoes of inherited symbiotic microbes to block Plasmodium transmission. However, in …
Article scientifique
Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection
Female children and adults typically generate more efficacious immune responses to vaccines and infections than age-matched males, but also suffer …
Article scientifique
Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin
Streptococcus pneumoniae serotype 1 is the predominant cause of invasive pneumococcal disease in sub-Saharan Africa, but the mechanism behind its …
Article scientifique
The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC
The Democratic Republic of the Congo (DRC) harbors 11% of global malaria cases, yet little is known about the spatial …