1320 publication(s) trouvée(s)
Article scientifique
The impact of COVID-19 on clinical research for Neglected Tropical Diseases (NTDs): A case study of bubonic plague
BACKGROUND: Among the many collaterals of the COVID-19 pandemic is the disruption of health services and vital clinical research. COVID-19 …
Article scientifique
Sero-prevalence of anti-Leptospira antibodies and associated risk factors in rural Rwanda: A cross-sectional study
BACKGROUND: Leptospirosis is a zoonotic disease transmitted through the urine of wild and domestic animals, and is responsible for over …
Article scientifique
Morbidity associated with Schistosoma mansoni infection in north-eastern Democratic Republic of the Congo
BACKGROUND: Reducing morbidity is the main target of schistosomiasis control efforts, yet only rarely do control programmes assess morbidity linked …
Article scientifique
Rapid establishment of a frontline field laboratory in response to an imported outbreak of Ebola virus disease in western Uganda, June 2019
The Democratic Republic of the Congo (DRC) declared an Ebola virus disease (EVD) outbreak in North Kivu in August 2018. …
Article scientifique
Epidemiology of Schistosoma mansoni infection in Ituri Province, north-eastern Democratic Republic of the Congo
BACKGROUND: Schistosomiasis, caused by Schistosoma mansoni, is of great significance to public health in sub-Saharan Africa. In the Democratic Republic …
Article scientifique
Spatial analysis of G.f.fuscipes abundance in Uganda using Poisson and Zero-Inflated Poisson regression models
BACKGROUND: Tsetse flies are the major vectors of human trypanosomiasis of the form Trypanosoma brucei rhodesiense and T.b.gambiense. They are …
Article scientifique
Clinical epidemiological characteristics of mycetoma in Eastern Sennar locality, Sennar State, Sudan
Mycetoma epidemiological features remain uncharacterised. Few studies have been conducted in a community-based setting to explore the epidemiological features and …
Article scientifique
Canine leishmaniosis in Tunisia: Growing prevalence, larger zones of infection
BACKGROUND: Discovered by Nicolle and Comte in 1908 in Tunisia, Leishmania infantum is an intracellular protozoan responsible for zoonotic canine …
Article scientifique
Modelling the impact of fexinidazole use on human African trypanosomiasis (HAT) transmission in the Democratic Republic of the Congo
Gambiense human African trypanosomiasis is a deadly disease that has been declining in incidence since the start of the Century, …
Article scientifique
Evaluation of facial cleanliness and environmental improvement activities: Lessons learned from Malawi, Tanzania, and Uganda
The World Health Organization promotes the SAFE (Surgery, Antibiotics, Facial cleanliness, and Environmental improvements) strategy for trachoma control and prevention. …
Article scientifique
Evaluation of photography using head-mounted display technology (ICAPS) for district Trachoma surveys
BACKGROUND: As the prevalence of trachoma declines worldwide, it is becoming increasingly expensive and challenging to standardize graders in the …
Article scientifique
Effectiveness of Nifurtimox Eflornithine Combination Therapy (NECT) in T. b. gambiense second stage sleeping sickness patients in the Democratic Republic of Congo: Report from a field study
BACKGROUND: Nifurtimox-eflornithine combination therapy (NECT) for the treatment of second stage gambiense human African trypanosomiasis (HAT) was added to the …
Article scientifique
Macrophage migration inhibitory factor in Nodding syndrome
Nodding syndrome (NS) is a catastrophic and enigmatic childhood epilepsy, accompanied by multiple neurological impairments and neuroinflammation. Of all the …
Article scientifique
The extent of protective footwear use among school-age rural children at high risk for podoconiosis and socio-economic correlates: A household cross-sectional survey in Southern Ethiopia
BACKGROUND: Podoconiosis is preventable if genetically susceptible people wear shoes starting from an early age and do so consistently. However, …
Article scientifique
The implementation and impact of a pilot hydrocele surgery camp for LF-endemic communities in Ethiopia
BACKGROUND: Ethiopia aims to eliminate lymphatic filariasis by 2020, through a dual approach of mass drug administration to interrupt transmission …
Article scientifique
Prevalence of glucose-6-phosphate dehydrogenase deficiency (G6PDd), CareStart qualitative rapid diagnostic test performance, and genetic variants in two malaria-endemic areas in Sudan
Glucose-6-phosphate dehydrogenase deficiency (G6PDd) is the most common enzymopathy globally, and deficient individuals may experience severe hemolysis following treatment with …
Article scientifique
Exposure, hazard, and vulnerability all contribute to Schistosoma haematobium re-infection in northern Senegal
BACKGROUND: Infectious disease risk is driven by three interrelated components: exposure, hazard, and vulnerability. For schistosomiasis, exposure occurs through contact …
Article scientifique
Species diversity and distribution of schistosome intermediate snail hosts in The Gambia
There is a need for recent information on intermediate snail hosts of schistosomes in The Gambia; the previous studies were …
Article scientifique
Emergence of dengue virus serotype 2 in Mauritania and molecular characterization of its circulation in West Africa
The number of sporadic and epidemic dengue fever cases have reportedly been increasing in recent years in some West African …
Article scientifique
Schistosoma mansoni egg-derived extracellular vesicles: A promising vaccine candidate against murine schistosomiasis
Extracellular vesicles (EVs) are protein-loaded nano-scaled particles that are extracellularly released by eukaryotes and prokaryotes. Parasite's EVs manipulate the immune …