1320 publication(s) trouvée(s)
Article scientifique
Monitoring the elimination of human African trypanosomiasis at continental and country level: Update to 2018
BACKGROUND: In 2012 human African trypanosomiasis (HAT), also known as sleeping sickness, was targeted for elimination as a public health …
Article scientifique
Performance evaluation of a prototype rapid diagnostic test for combined detection of gambiense human African trypanosomiasis and malaria
BACKGROUND: Malaria is endemic in all regions where gambiense or rhodesiense human African trypanosomiasis (HAT) is reported, and both diseases …
Article scientifique
Praziquantel and risk of visual disorders: Case series assessment
INTRODUCTION: Praziquantel has been in use by helminthiasis and schistosomiasis control programs for about 30 years. Although deemed to be …
Article scientifique
Elucidating the possible mechanism of action of some pathogen box compounds against Leishmania donovani
Leishmaniasis is one of the Neglected Tropical Diseases (NTDs) which is closely associated with poverty and has gained much relevance …
Article scientifique
Gender norms and mass deworming program access in Comé, Benin: A qualitative assessment of gender-associated opportunities and challenges to achieving high mass drug administration coverage
The World Health Organization's Neglected Tropical Disease Roadmap has accelerated progress towards eliminating select neglected tropical diseases (NTDs). This momentum …
Article scientifique
Field evaluation of DNA detection of human filarial and malaria parasites using mosquito excreta/feces
We recently developed a superhydrophobic cone-based method for the collection of mosquito excreta/feces (E/F) for the molecular xenomonitoring of vector-borne …
Article scientifique
Host genetic susceptibility to mycetoma
Mycetoma is one of the badly neglected tropical diseases, characterised by subcutaneous painless swelling, multiple sinuses, and discharge containing aggregates …
Article scientifique
Genomic analysis of natural intra-specific hybrids among Ethiopian isolates of Leishmania donovani
Parasites of the genus Leishmania (Kinetoplastida: Trypanosomatidae) cause widespread and devastating human diseases. Visceral leishmaniasis due to Leishmania donovani is …
Article scientifique
Evidence of the absence of human African trypanosomiasis in two northern districts of Uganda: Analyses of cattle, pigs and tsetse flies for the presence of Trypanosoma brucei gambiense
BACKGROUND: Large-scale control of sleeping sickness has led to a decline in the number of cases of Gambian human African …
Article scientifique
Investigating barriers and challenges to the integrated management of neglected tropical skin diseases in an endemic setting in Nigeria
BACKGROUND: There is a dearth of experience in and evidence for cost-effective integrated community-based management of skin neglected tropical diseases …
Article scientifique
Assessing expanded community wide treatment for schistosomiasis: Baseline infection status and self-reported risk factors in three communities from the Greater Accra region, Ghana
BACKGROUND: This paper reports on the baseline prevalence and associated risk factor findings of a pilot, longitudinal study exploring community-wide …
Article scientifique
Evaluation of copromicroscopy and serology to measure the exposure to Ascaris infections across age groups and to assess the impact of 3 years of biannual mass drug administration in Jimma Town, Ethiopia
BACKGROUND: The scientific community has recently summarized the desired characteristics for diagnostic tools across the different phases of a soil-transmitted …
Article scientifique
Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018
BACKGROUND: Intestinal parasites such as Cryptosporidium spp., Giardia lamblia and Entamoeba histolytica can cause severe diarrhea, especially among children in …
Article scientifique
Mycetoma in Uganda: A neglected tropical disease
Mycetoma is considered a neglected tropical disease globally. However, data on its burden and the associated complications in Uganda are …
Article scientifique
Risk factors for acute human brucellosis in Ijara, north-eastern Kenya
Brucellosis is an important zoonotic disease globally, with particularly high burdens in pastoral settings. While the zoonotic transmission routes for …
Article scientifique
Ecology of domestic dogs Canis familiaris as an emerging reservoir of Guinea worm Dracunculus medinensis infection
Global eradication of human Guinea worm disease (dracunculiasis) has been set back by the emergence of infections in animals, particularly …
Article scientifique
Non-typhoidal Salmonella bloodstream infections in Kisantu, DR Congo: Emergence of O5-negative Salmonella Typhimurium and extensive drug resistance
BACKGROUND: Non-typhoidal Salmonella (NTS) are a major cause of bloodstream infection (BSI) in sub-Saharan Africa. This study aimed to assess …
Article scientifique
Host immune responses during Taenia solium Neurocysticercosis infection and treatment
Taenia solium cysticercosis and taeniasis (TSCT), caused by the tapeworm T. solium, is a foodborne and zoonotic disease classified since …
Article scientifique
Economic benefits and costs of surgery for filarial hydrocele in Malawi
BACKGROUND: Lymphatic filariasis (LF) is endemic in 72 countries of Africa, Asia, Oceania, and the Americas. An estimated 25 million …
Article scientifique
Design of multi-epitope peptides containing HLA class-I and class-II-restricted epitopes derived from immunogenic Leishmania proteins, and evaluation of CD4+ and CD8+ T cell responses induced in cured cutaneous leishmaniasis subjects
Human leishmaniasis is a public health problem worldwide for which the development of a vaccine remains a challenge. T cell-mediated …