1320 publication(s) trouvée(s)
Article scientifique
Trachomatous trichiasis surgeons appreciate using HEAD START for extended training during periods of low surgical activity: A preliminary study
BACKGROUND: Trachomatous trichiasis (TT) surgeons routinely experience periods of low surgical activity, which may contribute to low or variable surgical …
Article scientifique
Liver and bladder morbidity in a Schistosoma mansoni and haematobium co-endemic area in the Democratic Republic of Congo
BACKGROUND: Both Schistosoma (S.) mansoni and S. haematobium are co-endemic in many regions of the Democratic Republic of the Congo …
Article scientifique
Molecular docking approaches in mycetoma: Toward improved patient management
Mycetoma is a neglected tropical disease characterised by chronic, granulomatous inflammation of the subcutaneous tissues, often leading to disfigurement, disability, …
Article scientifique
Reaching the last mile with ivermectin mass drug administration against onchocerciasis: The case of Kwanware-Ottou persistent transmission focus in the Wenchi health district of Ghana
BACKGROUND: Despite over two decades of Community-Directed Treatment with Ivermectin (CDTI), onchocerciasis transmission persists in localized pockets in Ghana, particularly …
Article scientifique
Social, environmental and policy contexts affecting the feasibility and acceptability of improving household flooring for better health in rural Kenya
BACKGROUND: Homes with unimproved floors (earth, sand, or clay) are associated with increased risks of soil-transmitted parasites and enteric infections, …
Article scientifique
Evaluation of surveillance-response interventions for Schistosoma haematobium elimination on Pemba Island, Tanzania: A 4-year intervention study with repeated cross-sectional surveys
BACKGROUND: The Zanzibar islands, Tanzania, have eliminated schistosomiasis as a public health problem since 2017 and need to rethink their …
Article scientifique
Early vascular toxicity induced by Bothrops atrox venom in the chorioallantoic membrane assay: Kinetic profile and translational insights
BACKGROUND: Snakebite envenoming is a neglected tropical disease with significant morbidity and mortality, particularly in areas with limited resources. Bothrops …
Article scientifique
Systemic inflammatory markers of visceral leishmaniasis treatment response in East Africa
BACKGROUND: Visceral leishmaniasis (VL) is the most severe form of leishmaniasis, with East Africa accounting for ~70% of global burden. …
Article scientifique
Strengthening health systems through NTD integration: Key insights from a multi-country webinar
The integration of Neglected Tropical Disease (NTD) control and elimination into national health systems is a strategic imperative, driven by …
Article scientifique
Exploring the health-seeking journeys of individuals affected by leprosy: Lived experiences in selected urban rehabilitation centers in Ethiopia
BACKGROUND: Despite widely available and effective treatment, leprosy remains a major public health issue in Ethiopia. The disease is often …
Article scientifique
Statistical methods for predicting the presence of Salmonella Typhi in wastewater samples at Asante Akyem Agogo, Ghana
BACKGROUND: Monitoring wastewater is vital for tracking typhoid fever in endemic areas. This study evaluated the performance of both spatial …
Article scientifique
Implementation of good clinical practice in clinical research in the context of limited resources settings: Lessons learnt from the freeBILy trial using an embedded mixed methods approach
INTRODUCTION: Limited financial and human resources and infrastructure can affect the implementation of Good Clinical Practice (GCP), which can have …
Article scientifique
Establishing a filarial clinical research platform in a resource-limited setting: Lessons and experiences from Tanzania
This paper examines the establishment and lessons learned from the LeDoxy Trial, a multinational, double-blind, randomized, placebo-controlled study that evaluated …
Article scientifique
Bleeding rectal polyp as an atypical presentation of intestinal schistosomiasis: A case report from Egypt
BACKGROUND: Schistosomiasis remains an important public health challenge in Egypt despite decades of control programs. Intestinal involvement is relatively common …
Article scientifique
Evaluating paratransgenesis using engineered symbiotic bacteria for Plasmodium inhibition in mosquito vectors: A systematic review
Malaria is a significant health problem in the world and has been increased by the emerging resistance to insecticides and …
Article scientifique
Mpox knowledge and positive attitudes in Sub-Saharan African healthcare workers after 2022 outbreak of disease: A systematic review and meta-analysis
BACKGROUND: Mpox remains a public health emergency of international concern, especially in regions beyond its usual endemic areas in Africa. …
Article scientifique
Soil-transmitted helminth infections and nutritional status of school-age children, in Mekhoni town, Tigray, Ethiopia
BACKGROUND: Soil-transmitted helminths pose a significant public health challenge among school-age children in developing countries, such as Ethiopia. This study …
Article scientifique
Cutaneous Leishmaniasis in Tigray, Ethiopia: Clinical patterns, environmental drivers and public health implications
BACKGROUND: Cutaneous leishmaniasis (CL) is a vector-borne skin disease caused by the bite of female sandflies infected with the Leishmania …
Article scientifique
Assessment of the efficacy and safety of two albendazole regimens for the treatment of hypermicrofilaraemic loiasis in adults in Woleu-Ntem Province, Gabon: A phase IIb single-blind randomised controlled trial
BACKGROUND: Loa (L.) loa hypermicrofilaraemia (≥ 8,000 mf/mL) increases the risk of severe adverse events during mass ivermectin administration for …
Article scientifique
Cost comparison of school-based mass drug administration of albendazole and ivermectin versus albendazole alone for soil-transmitted helminth control in Uganda
The co-administration of albendazole and ivermectin (ALB-IVM) is recommended for the treatment of soil-transmitted helminth (STH) infections, especially where the …