1320 publication(s) trouvée(s)
Article scientifique
Elimination within reach: A cross-sectional study highlighting the factors that contribute to persistent lymphatic filariasis in eight communities in rural Ghana
BACKGROUND: Despite the progress achieved in scaling-up mass drug administration (MDA) for lymphatic filariasis (LF) in Ghana, communities with persistent …
Article scientifique
A randomized trial of AmBisome monotherapy and AmBisome and miltefosine combination to treat visceral leishmaniasis in HIV co-infected patients in Ethiopia
BACKGROUND: Visceral leishmaniasis (VL) in human immunodeficiency virus (HIV) co-infected patients requires special case management. AmBisome monotherapy at 40 mg/kg …
Article scientifique
Enteric infection and dysfunction—A new target for PLOS Neglected Tropical Diseases
The past decade has seen a dramatic increase in global attention to neglected tropical diseases, with remarkable momentum in policy, …
Article scientifique
The effects of prednisolone treatment on serological responses and lipid profiles in Ethiopian leprosy patients with Erythema Nodosum Leprosum reactions
BACKGROUND: Erythema nodosum leprosum (ENL) is a systemic inflammatory complication occurring mainly in patients with lepromatous leprosy (LL) and borderline …
Article scientifique
Sounding the alarm: Defining thresholds to trigger a public health response to monkeypox
Endemic to the Democratic Republic of the Congo (DRC), monkeypox is a zoonotic disease that causes smallpox-like illness in humans. …
Article scientifique
Human antibody reaction against recombinant salivary proteins of Phlebotomus orientalis in Eastern Africa
BACKGROUND: Phlebotomus orientalis is a vector of Leishmania donovani, the causative agent of life threatening visceral leishmaniasis spread in Eastern …
Article scientifique
Trend analysis of leprosy in Morocco between 2000 and 2017: Evidence on the single dose rifampicin chemoprophylaxis
BACKGROUND: Morocco has achieved the goal of leprosy elimination as a public health problem several years ago (less than 1 …
Article scientifique
Serological and PCR-based markers of ocular Chlamydia trachomatis transmission in northern Ghana after elimination of trachoma as a public health problem
BACKGROUND: Validation of elimination of trachoma as a public health problem is based on clinical indicators, using the WHO simplified …
Article scientifique
Urban yellow fever outbreak—Democratic Republic of the Congo, 2016: Towards more rapid case detection
BACKGROUND: Between December 2015 and July 2016, a yellow fever (YF) outbreak affected urban areas of Angola and the Democratic …
Article scientifique
Translating preventive chemotherapy prevalence thresholds for Schistosoma mansoni from the Kato-Katz technique into the point-of-care circulating cathodic antigen diagnostic test
BACKGROUND: Intervention guidelines against Schistosoma mansoni are based on the Kato-Katz technique. However, Kato-Katz thick smears show low sensitivity, especially …
Article scientifique
Monitoring the elimination of human African trypanosomiasis: Update to 2016
BACKGROUND: Human African trypanosomiasis (HAT) is a neglected tropical disease targeted for elimination 'as a public health problem' by 2020. …
Article scientifique
Exploring the effect of human and animal population growth on vector-borne disease transmission with an agent-based model of Rhodesian human African trypanosomiasis in eastern province, Zambia
This paper presents the development of an agent-based model (ABM) to investigate Trypanosoma brucei rhodesiense human African trypanosomiasis (rHAT) disease …
Article scientifique
Use of anthropophilic culicid-based xenosurveillance as a proxy for Plasmodium vivax malaria burden and transmission hotspots identification
Vector-borne diseases account for more than 17% of all infectious diseases, causing more than one million deaths annually. Malaria remains …
Article scientifique
Identification and characterization of Loa loa antigens responsible for cross-reactivity with rapid diagnostic tests for lymphatic filariasis
The Global Program to Eliminate Lymphatic Filariasis (LF) relies on rapid diagnostic tests (RDTs) to determine where annual mass drug …
Article scientifique
Removal of adult subconjunctival Loa loa amongst urban dwellers in Nigeria
Loiasis is a neglected tropical disease caused by infection with the filarial parasite Loa loa. It is a disease considered …
Article scientifique
Serological evidence of inter-epizootic/inter-epidemic circulation of Rift Valley fever virus in domestic cattle in Kyela and Morogoro, Tanzania
BACKGROUND: Tanzania is among the Rift Valley fever (RVF) epizootic/endemic countries in sub Saharan Africa, where RVF disease outbreaks occur …
Article scientifique
Vertical transmission of naturally occurring Bunyamwera and insect-specific flavivirus infections in mosquitoes from islands and mainland shores of Lakes Victoria and Baringo in Kenya
BACKGROUND: Many arboviruses transmitted by mosquitoes have been implicated as causative agents of both human and animal illnesses in East …
Article scientifique
Genetic characterization of Lassa virus strains isolated from 2012 to 2016 in southeastern Nigeria
Lassa virus (LASV) is endemic in parts of West Africa where it causes Lassa fever (LF), a viral hemorrhagic fever …
Article scientifique
Rodent control to fight Lassa fever: Evaluation and lessons learned from a 4-year study in Upper Guinea
Lassa fever is a viral haemorrhagic fever caused by an arenavirus. The disease is endemic in West African countries, including …
Article scientifique
On-going transmission of human onchocerciasis in the Massangam health district in the West Region of Cameroon: Better understanding transmission dynamics to inform changes in programmatic interventions
BACKGROUND: Massangam health district (HD), in the West Region of Cameroon, has received ivermectin mass drug administration (MDA) for 20 …