140 publication(s) trouvée(s)
Article scientifique
Serum IL-38 and the rs7599662 polymorphism: novel biomarkers for pediatric idiopathic nephrotic syndrome
BACKGROUND: Idiopathic nephrotic syndrome (INS) is the most common chronic glomerular disorder in children and is characterized by a variable …
Article scientifique
Hemodynamic effects of high frequency oscillatory ventilation versus conventional mechanical ventilation in term neonates with persistent pulmonary hypertension: a single-center randomized trial
BACKGROUND: We aimed to evaluate the hemodynamics in full-term neonates with persistent pulmonary hypertension (PPH) on high frequency oscillatory ventilation …
Article scientifique
Implementation of an antimicrobial stewardship program in Alexandria University Children’s Hospital: an interventional study
BACKGROUND: Antimicrobial resistance (AMR) represents a threat to global public health. The antibiotics' effectiveness against a variety of infections consequently …
Article scientifique
Basilar artery flow velocities and optic nerve sheath diameter as adjuvant tools for early diagnosis of hypoxic ischemic encephalopathy in neonates
OBJECTIVE: We investigated potentiality ultrasonography measured optic nerve sheath diameter (ONSD) and basilar artery (BA) velocities to identify neonates with …
Article scientifique
Evaluating the myocardial functions of the forgotten right ventricle in children with nephrotic syndrome utilizing traditional echocardiography, two-dimensional speckle tracking and three-dimensional echocardiography
BACKGROUND: Primary nephrotic syndrome (NS) is associated with systemic effects that may impact cardiac function, although several studies have explored …
Article scientifique
Clinical and molecular characterization of 14 Egyptian children with fructose-1,6-bisphosphatase deficiency
BACKGROUND: Fructose-1,6-bisphosphatase (FBP1) deficiency is a rare inherited disease characterized by recurrent episodes of lactic acidosis and ketotic hypoglycemia. To …
Article scientifique
Long-term cardiometabolic and bone health consequences of ketogenic diet in children with refractory epilepsy
BACKGROUND: Ketogenic diet (KD) is a well-tolerated and efficacious therapy for refractory epilepsy (RE). While numerous mild short-term side effects …
Article scientifique
Left ventricular myocardial functions in pediatric patients with primary nephrotic syndrome: a comprehensive evaluation using conventional echocardiography, two-dimensional speckle tracking, and three-dimensional echocardiography
BACKGROUND: Nephrotic syndrome (NS) has been linked to cardiac morbidity and mortality. However, early cardiac implications in NS were studied …
Article scientifique
The landscape of pediatric genetic white matter disorders at a tertiary referral hospital in Upper Egypt and the report of 31 novel variants
BACKGROUND: Leukodystrophies (LDs) and genetic leukoencephalopathies (GLEs) encompass the spectrum of genetic white matter disorders (GWMDs). Despite their clinical significance, …
Article scientifique
Cardioprotective effects of CoQ10 in pediatric patients with lysosomal storage disorders
BACKGROUND: Lysosomal storage disorders (LSDs) result from an accumulation of specific substrates, due to the inability to break them down …
Article scientifique
Neutrophil CD64 can be an early predictor for sepsis during febrile neutropenic episodes in children with cancer: a case control study
BACKGROUND: Febrile neutropenia (FN) is a common treatment-related complication in pediatric cancer patients with substantial morbidities and mortalities. Previous studies …
Article scientifique
Hemodynamically significant anemia as an indication of transfusion in preterm infants
BACKGROUND: To transfuse or not to transfuse premature infants" is still one of debatable issues in neonatal care that has …
Article scientifique
Efficacy of treating Helicobacter pylori infection on seizure frequency in children with drug-resistant idiopathic generalized epilepsy: a randomized controlled trial
BACKGROUND: Helicobacter pylori (H. pylori) causes chronic infection in more than half of the population worldwide. Accumulating body of evidence …
Article scientifique
Native kidney and graft survival in a cohort of Egyptian children with nephropathic cystinosis: national referral center experience
BACKGROUND: Nephropathic Cystinosis is a rare autosomal recessive lysosomal storage disorder. In addition to kidney dysfunction, this disorder can also …
Article scientifique
Effects of community-acquired pneumonia on biventricular cardiac functions in children
BACKGROUND: This study aimed to evaluate the effects of community-acquired pneumonia (CAP) on cardiac function in children and compare the …
Article scientifique
Metabolic consequences and nailfold capillary changes in children with familial Mediterranean fever
BACKGROUND: There's an increasing role of nailfold capillaroscopy in the evaluation of peripheral vascular disease in chronic inflammatory disorders. Familial …
Article scientifique
Incidence and predictors of respiratory tract infections among birth cohorts in Ethiopia, 2023
BACKGROUND: Respiratory tract infection (RTI) has been a predominant health problem worldwide, including Ethiopia. It is one of the major …
Article scientifique
How long does it take to start minimal enteral feeding in preterm Neonates admitted to NICUs in Southern Oromia, Ethiopia?
BACKGROUND: The timely initiation of trophic feeding (TF) is crucial for premature newborns, but challenging due to immaturity, respiratory instability, …
Article scientifique
Determinants of prolonged exclusive breastfeeding among children aged 6–23 months in 21 sub-saharan African countries: evidence from nationally representative data
BACKGROUND: Under-five mortality and malnutrition are more common in many low- and middle-income countries, highlighting the grave consequences of improper …
Article scientifique
Clinical manifestations in Egyptian Pompe disease patients: Molecular variability and enzyme replacement therapy (ERT) outcomes
BACKGROUND: Pompe disease is a rare genetic disorder caused by a deficiency of the enzyme acid alpha-glucosidase. This condition leads …
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