846 publication(s) trouvée(s)
Article scientifique
Molecular characterization of selected nasal isolates of methicillin-resistant Staphylococcus aureus (MRSA) from healthy students of a tertiary institution
Purpose: To investigate the incidence of methicillin-resistant Staphylococcus aureus (MRSA) and carry out molecular characterization in selected nasal isolates from …
Article scientifique
Effect of montelukast/budesonide formoterol powder inhalation in chronic obstructive pulmonary disease
Purpose: To investigate the clinical efficacy of montelukast/budesonide formoterol powder inhalation in treating chronic obstructive pulmonary disease (COPD) and its …
Article scientifique
Ethno-botanical survey of medicinal plants used traditionally in the treatment of mental disorders in Kano, Nigeria
Purpose: To identify medicinal plants used by traditional medicine practitioners to treat mental disorders within Kano metropolis, Nigeria.Methods: A semi-structured …
Article scientifique
Myrcene exerts anti-tumor effects on oral cancer cells in vitro via induction of apoptosis
Purpose: To investigate the anticancer potential of myrcene against oral cancer cells.Methods: The effect of myrcene on oral cancer cell …
Article scientifique
Irbesartan protects against type 2 diabetic nephropathy by regulating miR-93/VEGF and its downstream effectors
Purpose: To investigate the protective effect of irbesartan against type 2 diabetic nephropathy (T2DN), and the mechanism involved.Methods: Wistar rats …
Article scientifique
Breviscapine alleviates MPP+-induced damage and apoptosis of SH-SY5Y cells by activating Nrf2 pathway
Purpose: To investigate the role and mechanism of action of breviscapine (Brp) in 1-methyl-4- phenylpyridinium ion (MPP+)-induced cell injury in …
Article scientifique
CK1α protects cardiomyocytes in sepsis-induced myocardial depression by repressing the interaction of ATG5 with myD88/NF-kappaB signaling
Purpose: To explore the effects of casein kinase 1α (CK1α) on cardiomyocytes in sepsis-induced myocardial depression.Methods: Colorectal ligation puncture (CLP) …
Article scientifique
Dexmedetomidine relieves inflammatory response in rats with acute spinal cord injury through IKK/NF-κB signaling pathway
Purpose: To examine the effect of dexmedetomidine (DEX) on inflammatory response in spinal cord damage, and involvement of IKK/NF-κB signaling …
Article scientifique
Polygonum cuspidatum glycoside mitigated LPS-induced human endometrial stromal cell inflammation by regulating NF-κB/Nrf2 signaling pathway-related proteins
Purpose: To study the influence of polydatin on LPS-provoked human endometrial stromal cell inflammation, and its mechanism of action.Methods: Fifty …
Article scientifique
Clinical efficacy and inflammatory factors in knee osteoarthritis with glucosamine hydrochloride plus meloxicam
Purpose: To evaluate the efficacy and change in serum levels of inflammatory factors in knee osteoarthritis (KOA) treated with glucosamine …
Article scientifique
Buddleoside inhibits TLR4-related pathway in a mouse model of acute liver failure, promotes autophagy, and inhibits inflammation
Purpose: To study the inhibitory influence of buddleoside on TLR4-associated pathway, autophagy and inflammation in a mouse model of acute …
Article scientifique
Minocycline inhibits nerve cell apoptosis caused by intracerebral hemorrhage in young mice via TRAIL signaling pathway
Purpose: To investigate the influence of minocycline on nerve cell apoptosis caused by intracerebral hemorrhage (ICH) in young mouse model, …
Article scientifique
Effect of tiotropium bromide, N-acetylcysteine and respiratory training on pulmonary function, activity tolerance and quality of life of patients with chronic obstructive pulmonary disease
Purpose: To investigate the effect of application of tiotropium bromide and N- acetylcysteine in combination with respiratory training on the …
Article scientifique
Antiallergic effects of ethanol extract of Cnidium monnieri (L.) Cuss. on DNCB-induced atopic dermatitis in mice
Purpose: To study the anti-allergic effects of ethanol extract of Cnidium monnieri (L.) Cuss. on 2, 4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis …
Article scientifique
MicroRNA-300 inhibits the metastasis of prostate cancer through the regulation of TRIM63
Purpose: To investigate the role of microRNA-300 in the tumorigenesis of prostate cancer (PCa), and the relationship between microRNA-300 level …
Article scientifique
Pharmacological evaluation of Typha domingensis for its potentials against diet-induced hyperlipidemia and associated complications
Purpose: To evaluate the hyperlipidemic potential of the methanolic-aqueous extract of Typha domingensis Pers.Method: Hyperlipidemia was induced in Wistar rats …
Article scientifique
Hypoglycemic, analgesic and anti-inflammatory effects of Pulicaria incisa (Lam.) DC extracts in animal models
Purpose: To investigate acute toxicity, hypoglycaemic, analgesic and anti-inflammatory activities of Pulicaria incisa (Lam.) DC.Methods: Acute toxicity analysis was assessed …
Article scientifique
Effect of tocilizumab treatment for COVID-19-induced acute respiratory distress syndrome (ARDS) on renal function of patients
Purpose: To study the effect of tocilizumab (TCZ) on the renal function of patients with severe coronavirus disease 2019 (COVID-19) …
Article scientifique
Isolation of a pentacyclic triterpenoid from the antiplasmodial bioactive fraction of Nauclea latifolia (Sm) roots
Purpose: To research the antiplasmodial property of aqueous extract, fractions, and residue of Nauclea latifolia roots and to isolate the …
Article scientifique
Inhibitory activity of CXCR4 attenuates intervertebral disc degeneration by regulating TXNIP/NLRP3 expression
Purpose: To explore the inhibitory effect and mechanism of action of CXCR4 on intervertebral disc degeneration.Methods: The expression of CXCR4 …