846 publication(s) trouvée(s)
Article scientifique
Dexmedetomidine inhibits oxidative stress in sepsis-induced acute kidney injury in rats by regulating GSK-3β/Nrf2/ARE axis
Purpose: To determine the effect of dexmedetomidine on sepsis-mediated acute kidney injury (SAKI) in rats. Methods: Twenty-four SD rats were …
Article scientifique
Effect of sodium butyrate on glucose and lipid metabolism, insulin expression and apoptosis of β-cells in obese pregnant rats
Purpose: To study the influence of sodium butyrate on the metabolism of lipid and glucose, insulin expression and apoptosis of …
Article scientifique
Isoxanthohumol exerts anticancer activity against drug-resistant thyroid cancer cells by inhibiting cell migration and invasion, apoptosis induction and targeting PI3K/AKT/m-TOR signaling pathway
Purpose: To investigate the anticancer effect of isoxanthohumol against drug-resistant thyroid cancer cells. Its effect on cellular PI3K/AKT/m-TOR signaling pathway, …
Article scientifique
Signal processing techniques for the spectrophotometric quantitation of binary mixture of dapagliflozin and saxagliptin: A comparative study
Purpose: To investigate the advantages and drawbacks of four signal processing methods for spectrophotometric quantitation of mixtures of dapagliflozin and …
Article scientifique
Glyphaea brevis (Spreng) Monachino (Tiliaceae) leaf fractions protect against pentylenetetrazole (PTZ)-induced convulsion in mice
Purpose: To investigate the anticonvulsant effect of Glyphaea brevis leaf fractions using a pentylenetetrazole (PTZ)-induced seizure model in mice. Methods: …
Article scientifique
Comparative effect of propofol and sevoflurane on chronic postsurgical pain and cognitive function after cardiac surgery in Chinese elderly patients: A preliminary clinical study
Purpose: To compare the effects of propofol and sevoflurane on chronic post-surgical pain and cognitive function after cardiac surgery in …
Article scientifique
Effect of Dachaihu decoction on traditional Chinese medicine-related indices of Type 2 diabetes in rats, and elucidation of its mechanism of action
Purpose: To study the influence of Dachaihu decoction on traditional Chinese medicine (TCM)-related indices of type 2 diabetes mellitus (T2DM) …
Article scientifique
Blocking NLRP3 inflammasome expression by RAS-like protein A mitigates neuropathic pain in chronic constriction injury rat models
Purpose: To investigate the role of RAS-like protein A (RalA) in lipopolysaccharide-induced inflammatory regulation in primary microglia of chronic constriction …
Article scientifique
Extraction, biological activities and stability of Hylocereus polyrhizus peel extract as a functional food colorant and nutraceutical
Purpose: To study the biological effects and the stability of H.polyrhizus peel extract as a natural colorant and nutraceutical in …
Article scientifique
Vitamin D associated inflammation and atherosclerosis
Vitamin D is known to play a crucial role in mineral homeostasis and bone metabolism. Recent discoveries showed that the …
Article scientifique
Irigenin exhibits anticancer activity against human colon cancer cells via autophagy, inhibition of cell migration and invasion, and targeting of ERK/MAPK signal pathway
Purpose: To study the anticancer effect of naturally-occurring irigenin isoflavonoid on colon cancer, and to determine the mechanism involved. Methods: …
Article scientifique
Neuropharmacological evaluation of the methanol leaf extract of Phyllanthus muellerianus (Kuntze) Exell and its ethyl acetate fraction in mice
Purpose: To investigate the neuropharmacological effects of the methanol leaf extract (ME) and fractions of Phyllanthus muellerianus (PM) (Phyllanthaceae) (Kuntze) …
Article scientifique
Effect of the plant flavonoid, rhoifolin, on memory and cognition in a rat model of Alzheimer’s disease
Purpose: To investigate the neuroprotective effect of the natural flavonoid rhoifolin in rats with streptozotocin (STZ)-induced (AD). Methods: Morris water-maze …
Article scientifique
Evidence of anti-inflammatory and anti-ulcer properties of aerial parts of Centaurea tougourensis Boiss. and Reut.
Purpose: To determine the anti-inflammatory and anti-ulcer properties of the aerial parts of Centaurea tougourensis Boiss. & Reut. Methods: The …
Article scientifique
Studies on the pharmacokinetics of piperacillin/tazobactam in renal replacement therapy in patients with chronic renal failure
Purpose: To study the pharmacokinetics of piperacillin/tazobactam in renal replacement therapy (CRRT) in patients with chronic renal failure (CRF). Methods: …
Article scientifique
Computational design of phosphoinositide 3-kinase gamma (PI3Kg) inhibitors as a newer therapy for rheumatoid arthritis
Purpose: To develop a potential therapy for rheumatoid arthritis (RA) by altering factors involved in the pathogenesis of the disease. …
Article scientifique
Effect of propofol on lung metastasis of circulating tumor cells after colorectal cancer surgery
Purpose: To investigate the effect of propofol on lung metastasis of circulating tumor cells (CTCs) after colorectal cancer (CRC) surgery, …
Article scientifique
Effect of soil type on chemical composition and antioxidant properties of Solanum nigrum (L.) shoot oil extracts
Purpose: To investigate the effect of different soil textures on chemical composition and antioxidant properties of essential oils from Solanum …
Article scientifique
Inhibitory effect and mechanism of action of tanshinone IIA on human bladder cancer cell J82
Purpose: To investigate the therapeutic influence of tanshinone IIA on human bladder cancer cell J82, and the possible signal route …
Article scientifique
Silencing CDCA8 inhibits the proliferation and invasion of gastric cancer cells and induces apoptosis by blocking the Akt pathway
Purpose: To investigate the effect of cell division cycle associated 8 (CDCA8) on malignant progression of gastric cancer (GC) cells. …