846 publication(s) trouvée(s)
Article scientifique
Isoglycyrrhizin protects mouse lungs against acute respiratory distress syndrome via regulation of AMPK/Nrf2/ARE pathway
Purpose: To study the effect of isoglycyrrhizin on LPS-mediated acute respiratory distress syndrome (ARDS) in a mouse model, as well …
Article scientifique
Fasudil ameliorated liposaccharide-induced acute kidney injury in mice by inhibiting NLRP3
Purpose: To determine the influence of fasudil on LPS-mediated acute kidney injury (AKI) in mice.Methods: Healthy C57 mice (n = …
Article scientifique
MiR-140-5p inhibits morphine tolerance in rats by targeting TLR4
Purpose: To determine the influence of miR-140-5p on morphine tolerance in rats.Methods: Sprague-Dawley (SD) rats were randomly divided into morphine …
Article scientifique
Dioscorea deltoidei (Dioscoreaceae) leaf extract exerts anti-atherosclerotic effect in rats via down-regulation of phosphorylated JAK/STAT
Purpose: To investigate the effect of leaf extract of Dioscorea deltoidea (Dioscoreaceae) leaf (DDE) on atherosclerosis-induced aorta wall damage in …
Article scientifique
Oxytocin protects neurons from hypoxic-ischemic brain injury by enhancing inhibitory neurotransmission in neonatal rats
Purpose: To study the protective effect of oxytocin on hypoxic-ischemic brain neuron injury in neonatal rats, and the mechanism of …
Article scientifique
Comparison of efficacy and safety of general anesthesia alone with those of combined epidural/general anesthesia in Chinese patients with gastric cancer undergoing laparoscopy-assisted tumor resection
Purpose: To compare postoperative opioid consumption, inflammatory response, survival/clinical outcomes and safety profile of epidural combined with general anesthesia (GA) …
Article scientifique
Resveratrol ameliorates necrotizing enterocolitis in neonatal rats through regulation of inflammatory and apoptotic pathways
Purpose: To determine the efficacy of resveratrol in mitigating necrotizing enterocolitis (NEC) in neonatal rats.Methods: Necrotizing enterocolitis (NEC) was induced …
Article scientifique
Forsythiaside A inhibits hydrogen peroxide-induced inflammation, oxidative stress, and apoptosis of cardiomyocytes
Purpose: To investigate the effect of forsythiaside A on heart failure.Methods: An in vitro cell model of myocardial injury was …
Article scientifique
Clinico-toxicological effects of ceftriaxone after intramuscular administration of graded doses in Basenji dogs
Purpose: The recent ceftriaxone-induced anaemia and mortalities at the dose of 50 mg/kg in Veterinary Teaching Hospital, University of Nigeria …
Article scientifique
Therapeutic efficacy of a combination of mesalazine and Bifid Triple Viable Capsules (BTVCs) on ulcerative colitis patients, and its effect on inflammation and oxidative stress
Purpose: To determine the curative impact of mesalazine (MSZ)-BTVCs combination on ulcerative colitis (UC), and its influence on inflammation and …
Article scientifique
Clinical efficacy of a combination of propofol and etomidate in pediatric anesthesia, and its effect on vital indices in patients
Purpose: To study the clinical effectiveness of a combination of propofol and etomidate as pediatricanesthesia, and its influence on some …
Article scientifique
Efficacy of a combination of sildenafil and magnesium sulfate in the treatment of persistent pulmonary hypertension of the newborn, and its influence on hemodynamics
Purpose: To investigate the efficacy of the combined use of sildenafil and magnesium sulfate in the treatment of persistent pulmonary …
Article scientifique
Leflunomide inhibits inflammation and apoptosis of H9c2 cells induced by hydrogen peroxide
Purpose: To investigate the effects of leflunomide (Lef) on inflammatory response and apoptosis after myocardial infarction, and to explore its …
Article scientifique
Trichostatin A reduces nerve cell apoptosis in depressive rats by regulating CREB/BDNF signaling pathway
Purpose: To investigate the influence of trichostatin A on nerve cell apoptosis in depressive rats and to explore the probable …
Article scientifique
Klotho protects chondrocyte viability via FOXO1/3 in osteoarthritis
Purpose: To investigate the effect of Klotho and FOXO1/3 on the CH viability in OA.Methods: The survival rate of CHs, …
Article scientifique
Therapeutic effect of a combination of montelukast and vitamins A and D drops in children with bronchial asthma, and its influence on quality of life
Purpose: To investigate the efficacy of a combination of montelukast and vitamins A and D drops in bronchial asthma children, …
Article scientifique
Differential expressions of TGF-β1, HIF-1, VEGF, α-SMA and E-cadherin in renal tissues of a neonatal rat model of hydronephrosis
Purpose: To investigate the differential expressions of transforming growth factor-β1 (TGF-β1), hypoxia inductive factor-1 (HIF-1), vascular endothelial growth factor (VEGF), …
Article scientifique
Effects of different doses of dexmedetomidine on postsurgical emergence agitation and oxidative stress in children
Purpose: To study the effects of various dexmedetomidine (DEX) doses on post-surgical emergence agitation (EA) and oxidative stress in children.Methods: …
Article scientifique
Protective effect of S-allyl cysteine against cerebral ischemia/reperfusion injury in experimental rats
Purpose: To investigate the protective effect of S-allyl cysteine (SAC) against cerebral ischemiareperfusion injury (CRI) in rats.Methods: The protective effect …
Article scientifique
Design, synthesis and cytotoxic evaluation of 2-amino-4- aryl-6-substituted pyridine-3,5-dicarbonitrile derivatives
Purpose: To synthesize novel pyridine derivatives and evaluate their efficiency as potent inhibitors of cyclin dependent kinase 2 (CDK2) enzyme …