846 publication(s) trouvée(s)
Article scientifique
Esomeprazole improves the acidic microenvironment of epithelial ovarian cancer by inhibiting the expression of VATPase
Purpose: To determine the effect of esomeprazole on apoptosis of ovarian cancer cells and their sensitivity to paclitaxel, and the …
Article scientifique
An overview of some medicinal plants and isolated active compounds with potential antiprotozoal activity
Diarrhoea associated illness presents with mortality and morbidity in rural communities in most low income countries especially in children < …
Article scientifique
MiR-28-3p enhances healing of fracture via negative regulation of the target gene Sox6 and activation of PI3K/Akt signaling pathway
Purpose: To investigate the effect of miR-28-3p on fracture healing, and the involvement of Sox6 gene and PI3K/Akt signaling pathway …
Article scientifique
Mitigating effect of metformin on polycystic ovarian syndrome and insulin resistance in rats, and the mechanisms involved
Purpose: To study the effect of metformin on polycystic ovarian syndrome (PCOS) and insulin resistance (IR) in rats, and the …
Article scientifique
Phytochemical composition and pharmacological assessment of callus and parent plant of Asteriscus graveolens (Forssk.) Less. from Algerian Sahara
Purpose: To determine the phytochemical composition, acute toxicity, as well as analgesic and antiinflammatory properties of extracts of the aerial …
Article scientifique
Strategic analysis of clinical pharmacy education in Saudi Arabia
Purpose: To analyze the strategic position of clinical pharmacy education in Saudi Arabia and ensure that it meets the needs …
Article scientifique
Oxidative degradation of some antibiotics by permanganate ion in alkaline medium: A kinetic and mechanistic approach
Purpose: To investigate the kinetics of oxidative removal of two β-lactam antibiotics (A), namely, ampicillin and flucloxacillin.Methods: In this study, …
Article scientifique
Baicalein inhibits cell development in papillary thyroid cancer by regulating miR-206/RAP1B pathway
Purpose: To investigate the therapeutic effect of baicalein on papillary thyroid cancer (PTC) cells in vitro and its underlying molecular …
Article scientifique
Chemical composition of the volatile oil of Chenopodium ambrosioides L. from Mianyang in Sichuan Province of China and its sub-chronic toxicity in mice
Purpose: To determine the chemical constituents of the volatile oil of Chenopodium ambrosioides L. from Mianyang in Sichuan Province of …
Article scientifique
Quality of life of patients with chronic kidney disease in two health facilities in Delta State, Nigeria
Purpose: To determine patients’ quality of life (QoL), impact of socio-demographic characteristics as well as biochemical parameters on the quality …
Article scientifique
Effect of berberine on hyperandrogenemia, ovulation dysfunction and inflammation in a mouse model of polycystic ovary syndrome
Purpose: To study the effect of berberine (BBR) on hyperandrogenemia (HA), ovulation dysfunction and inflammation in a mouse model of …
Article scientifique
Medication Adherence and Health Status in HIV Positive Patients in Akwa Ibom State, Nigeria
Purpose: To assess medication adherence and health status in ambulatory HIV positive patients in Akwa Ibom State, Nigeria.Methods: The 7-item …
Article scientifique
Antidepressant effect of methanol root bark extract of Acacia seyal Del. (Fabaceae): Possible involvement of the inflammatory pathway
Purpose: To study the involvement of inflammatory pathways in the antidepressant activity of Acacia seyal in mice.Methods: The median lethal …
Article scientifique
Suppressive efficiency of Kojic acid from Aspergillus tamarii MM11 against HepG-2 cell line derived from human liver cancer
Purpose: To evaluate the antioxidant and cytotoxic properties of Kojic acid (KOJIC ACID) from Aspergillus tamarii MM11 against HepG-2 cell …
Article scientifique
Saussurea lappa Clarke extract exhibits potent antioxidant effect and attenuates neuroinflammatory responses in lipopolysaccharide-stimulated microglial cells
Purpose: To investigate the antioxidant and anti-neuroinflammatory potential of Saussurea lappa Clarke (SLC-EA) extract in LPS-stimulated BV-2 microglial cells.Methods: Cell …
Article scientifique
Novel cholinesterase inhibitory effect of α-spinasterol isolated from the leaves of Acacia auriculiformis A. CUNN Ex. Benth (Fabaceae)
Purpose: To investigate the in vitro anticholinesterase, α-glucosidase and antioxidant activities of α-spinasterol isolated from Acacia auriculiformis leaves.Methods: The powdered …
Article scientifique
An ethnopharmacological review of Hyptis suaveolens (L.) Poit
This review aimed to provide a comprehensive overview of ethnobotanical uses, chemical constituents, posology, and toxicology of Hyptis suaveolens, and …
Article scientifique
Paclitaxel liposomes exert radio-sensitization effect on breast cancer cell line SK-BR-3 by regulating expressions of apoptotic proteins
Purpose: To study the radio-sanitization effect of paclitaxel liposomes on breast cancer cells, SK-BR-3.Methods: Breast cancer cell line SK-BR-3 was …
Article scientifique
Cordycepin reverses cisplatin resistance in human bladder cancer cells via the PTEN/PI3K/AKt pathway
Purpose: To study the influence of cordycepin (Cor) on cisplatin insensitivity in bladder carcinoma, and its underlying mechanism of action.Methods: …
Article scientifique
An oral vaccine against CVA16 (Coxsackievirus A16) was developed by constructing a recombinant Lactococcus lactis
Purpose: To develop an oral vaccine against CVA16 (Coxsackievirus A16) by constructing a recombinant Lactococcus lactis that expresses VP1 from …