Sciences de la santé

Article scientifique

Case Report: Primary bile acid synthesis defect: first cases series from Tunisia

Background Primary bile acid synthesis defects (BASD) are autosomal recessive disorders causing cholestatic liver disease and fat-soluble vitamin malabsorption. Despite …

2026 Open Access

Article scientifique

Systemic–local immune remodeling in colorectal cancer: CD14+ cell-derived cytokine responsiveness, mucosal immune-cell organization, and exploratory metastasis-associated patterns

Background: Immune regulatory networks contribute to colorectal cancer (CRC) progression, but most clinical studies focus on tissue immune-cell abundance or …

2026 Open Access

Article scientifique

Advancing early identification of at-risk children: a consensus-based refinement and validation roadmap for the pediatric malnutrition screening algorithm

Introduction: Mild malnutrition risk remains an underrecognized yet clinically important contributor to impaired growth and development in children aged 1-10 …

2026 Open Access

Article scientifique

Electrophysiological Risk in Pediatric Intermittent versus Persistent Ventricular Pre-excitation: A Large Single-Center Cohort

2026 Open Access

Article scientifique

Steatotic liver disease in people with HIV at Tshepong Hospital: A post-mortem analysis

Background: Liver disease is the leading cause of non-AIDS-related mortality in people living with HIV (PLWH). Steatotic liver disease (SLD) …

2024 Open Access

Article scientifique

“The COVID-19 pandemic in BRICS: Milestones, interventions, and molecular epidemiology”

Brazil, Russia, India, China, and South Africa (BRICS) are a group of developing countries with shared economic, healthcare, and scientific …

2024 Open Access

Article scientifique

Optimizing peer-led health interventions: A social network analysis approach for identifying influential fishermen in Malawi

Social network interventions (SNIs) can leverage influential individuals within personal networks to amplify health behavior adoption and intervention diffusion. While …

2026 Open Access

Article scientifique

Contextual factors influencing schistosomiasis treatment and identification of delivery platforms for arpraziquantel in hard-to-reach areas and populations in Homa Bay County, Kenya

A new formulation of praziquantel, arpraziquantel (arPZQ), has been developed for preschool-aged children (PSAC) to fill the treatment gap for …

2024 Open Access

Article scientifique

PHENOPLASTICITY AND KARYOTYPING OF CONVOLVULUS ARVENSIS L., 1753 (SOLANALES, CONVOLVULACEAE) GENOTYPES

Convolvulus arvensis L., 1753 (Solanales, Convolvulaceae) is a cosmopolitan polymorphic perennial herb and one of 15 noxious crop weeds. The …

2024 Open Access

Article scientifique

Graduate perceptions of their interprofessional practice: Lessons for undergraduate training

BACKGROUND: Interprofessional education (IPE) during undergraduate training (UGT) is considered important for new graduates to collaborate inter-professionally. There are, however, …

2024 Open Access

Article scientifique

Determinant factors of the longitudinal pulse pressure among hypertensive patients treated at Assosa general hospital, Western Ethiopia

BACKGROUND: Hypertension is a common, long-term condition that tends to be associated with age and can lead to significant cardiovascular …

2024 Open Access

Article scientifique

Barriers and opportunities to addressing social determinants of malaria in Wakiso District, Uganda

Malaria remains a significant public health threat in sub-Saharan Africa, particularly in Uganda, where it is the leading cause of …

2026 Open Access

Article scientifique

Promoting playfulness through a play-based occupational therapy intervention: A study protocol

Background: Play is integral to optimal childhood development. Occupational therapists often use play to improve play skills. However, when it …

2024 Open Access

Article scientifique

Researchers’ perspectives on the integration of molecular and genomic data into malaria elimination programmes in Africa: a qualitative study

BACKGROUND: Malaria remains a significant public health concern, despite global efforts to combat the disease with highest burden in Africa. …

2024 Open Access

Article scientifique

Influence of government policies on handwashing and vaccine uptake in Kenya, Uganda, and Tanzania to prevent and control COVID-19: a systematic review

Introduction: The government's role in influencing policies related to Coronavirus disease 2019 (COVID-19) vaccine distribution and handwashing practices is essential …

2024 Open Access

Article scientifique

Effectiveness of dissemination strategies of maternal clinical guidelines: A narrative review

BACKGROUND: Maternal clinical guidelines (MCGs) provide evidence-based recommendations for skilled birth professionals (SBPs) at the point of care. The dissemination …

2024 Open Access

Article scientifique

Integrated experimental and computational evaluation of atractylenolide III from Tubipora musica for anticancer lead identification

Abstract Hepatocellular carcinoma (HCC) remains a major global health challenge, with over 900,000 new cases annually and a pronounced male …

2026 Open Access

Article scientifique

Sexual and Family Planning Autonomy and Efficacy Among Married Women in Ethiopia: Psychometric Validation, Correlates, and the Autonomy-Efficacy Gap

2026 Open Access

Article scientifique

Compassion fatigue among oncology staff at Universitas Academic Hospital Annex

Background: Compassion fatigue (CF) and burnout are prevalent in the field of oncology, particularly among nurses and oncologists. Compassion fatigue …

2026 Open Access

Article scientifique

Enhancing West African family medicine curriculum through entrustable professional activities

The training of Family Medicine residents in the West Africa College of Physicians (WACP) has steadily upscaled to a competency-based …

2024 Open Access