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814 publication(s) trouvée(s)
Article scientifique
Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
BACKGROUND: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery …
Article scientifique
Global Health Diplomacy, Monitoring & Evaluation, and the Importance of Quality Assurance & Control: Findings from NIMH Project Accept (HPTN 043): A Phase III Randomized Controlled Trial of Community Mobilization, Mobile Testing, Same-Day Results, and Post-Test Support for HIV in Sub-Saharan Africa and Thailand
BACKGROUND: Provision and scale-up of high quality, evidence-based services is essential for successful international HIV prevention interventions in order to …
Article scientifique
Enhancing future acceptance of rural placement in Tanzania through peripheral hospital rotations for medical students
BACKGROUND: Mal-distribution of health care workers is a global health challenge that exacerbates health disparities, especially in resource-limited settings. Interventions …
Article scientifique
High prevalence of hypertension and cardiovascular disease risk factors among medical students at Makerere University College of Health Sciences, Kampala, Uganda
BACKGROUND: Cardiovascular disease has become a leading global health challenge representing the largest cause of mortality in adults worldwide. Non …
Article scientifique
Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance
BACKGROUND: Combating the spread of drug resistant tuberculosis is a global health priority. Whole genome association studies are being applied …
Article scientifique
Localization and interactions of Plasmodium falciparum SWIB/MDM2 homologues
BACKGROUND: Malaria remains a global health problem and the majority of deaths are caused by Plasmodium falciparum parasites. Due to …
Article scientifique
New approaches to measuring anthelminthic drug efficacy: parasitological responses of childhood schistosome infections to treatment with praziquantel
BACKGROUND: By 2020, the global health community aims to control and eliminate human helminthiases, including schistosomiasis in selected African countries, …
Article scientifique
Phase III evaluation of the insecticidal efficacy and durability of a deltamethrin-treated polypropylene long-lasting net LifeNet®, in comparison with long-lasting nets made from polyester and polyethylene: study protocol
BACKGROUND: Universal coverage of long-lasting insecticidal nets (LNs) made from polyester or polyethylene fibres has been adopted as the standard …
Article scientifique
Characterization of a novel inhibitory human monoclonal antibody directed against Plasmodium falciparum Apical Membrane Antigen 1
Abstract Malaria remains a major challenge to global health causing extensive morbidity and mortality. Yet, there is no efficient vaccine …
Article scientifique
Global health education in Germany: an analysis of current capacity, needs and barriers
BACKGROUND: In times of increasing global challenges to health, it is crucial to create a workforce capable of tackling these …
Article scientifique
Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses
BACKGROUND: Malaria, caused by Plasmodium falciparum, continues to have a devastating impact on global health, emphasizing the great need for …
Article scientifique
Validity of a Minimally Invasive Autopsy for Cause of Death Determination in Adults in Mozambique: An Observational Study
BACKGROUND: Despite global health efforts to reduce maternal mortality, rates continue to be unacceptably high in large parts of the …
Article scientifique
A Data-Driven Evaluation of the Stop TB Global Partnership Strategy of Targeting Key Populations at Greater Risk for Tuberculosis
OBJECTIVE: Identifying those infected with tuberculosis (TB) is an important component of any strategy for reducing TB transmission and population …
Article scientifique
Seeking order amidst chaos: a systematic review of classification systems for causes of stillbirth and neonatal death, 2009–2014
BACKGROUND: Each year, about 5.3 million babies die in the perinatal period. Understanding of causes of death is critical for …
Article scientifique
STING-Licensed Macrophages Prime Type I IFN Production by Plasmacytoid Dendritic Cells in the Bone Marrow during Severe Plasmodium yoelii Malaria
Malaria remains a global health burden causing significant morbidity, yet the mechanisms underlying disease outcomes and protection are poorly understood. …
Article scientifique
Granulomas and Inflammation: Host-Directed Therapies for Tuberculosis
Tuberculosis (TB) remains a leading global health problem that is aggravated by emergence of drug-resistant strains, which account for increasing …
Article scientifique
Training tomorrow’s leaders in global health: impact of the Afya Bora Consortium Fellowship on the careers of its alumni
BACKGROUND: Effective leadership is a cornerstone of successful healthcare delivery in resource limited settings throughout the world. However, few programs …
Article scientifique
Cannabidiol rather than Cannabis sativa extracts inhibit cell growth and induce apoptosis in cervical cancer cells
BACKGROUND: Cervical cancer remains a global health related issue among females of Sub-Saharan Africa, with over half a million new …
Article scientifique
Self-reported practices among traditional birth attendants surveyed in western Kenya: a descriptive study
BACKGROUND: The high rate of home deliveries conducted by unskilled birth attendants in resource-limited settings is an important global health …
Article scientifique
Risk factors for tuberculosis smear non-conversion in Eden district, Western Cape, South Africa, 2007–2013: a retrospective cohort study
BACKGROUND: Tuberculosis (TB) continues to be a major global health problem. While progress has been made to improve TB cure …