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7385 publication(s) trouvée(s)
Article scientifique
Awareness of the Importance of Genetic Counseling and Its Role in Preventing Genetic Disorders in Derna District
Abstract This study examined awareness, attitudes, and perceived barriers regarding genetic counseling among individuals in Derna District, focusing on its …
Éditorial
Editorial: Emerging pathogens and contaminants in the environment: human health risks, exposure pathways and epidemiological outcomes
After embarking on a Nigerian-based research project under the National Research Fund (NRF) of the TETFUND, Project Code TETF/DR&D CE/NRF/2020/SETI/99/VOL.1, …
Article scientifique
Pilot study: predicting the interplay between FOXO1 and its downstream long non-coding RNAs in HCC
Introduction Forkhead Box O-1 ( FOXO1 ) is one of the key regulatory transcription factors capable of regulating many critical …
Article scientifique
Whole-genome sequencing reveals genomic diversity and selection signatures for adaptation in South African Afrikaner and Bonsmara cattle
The indigenous Afrikaner and composite Bonsmara cattle breeds are hardy and adapted to the diverse South African climate and biomes. …
Article scientifique
Impact of COVID-19 on New – onset Type 1 diabetes mellitus: A six-year retrospective review from two Paediatric clinics, Kampala, Uganda
BACKGROUND: Type 1 Diabetes Mellitus is one of the most common chronic diseases in children, yet data from low-income countries …
Article scientifique
Circular bioeconomy-driven carotenoid production by Agrococcus sp. NP24 using cheese whey byproduct: process optimization and bioactivity assessment
Growing interest in the circular economy has promoted the use of agri-food wastes as fermentable and readily available substrates for …
Article scientifique
Genetic polymorphisms in DNA repair gene XRCC1 and the risk of diabetic polyneuropathy
Abstract This study aimed to investigate the association between XRCC1 Arg399Gln and Arg194Trp single nucleotide polymorphisms (SNPs) and the risk …
Article scientifique
Enhanced accumulation of anticancer compounds in C. roseus hairy root cultures through elicitation and precursor feeding
Catharanthus roseus is a medicinal plant known for producing numerous indole terpenoid alkaloids. This study investigated the effects of methyl …
Article scientifique
Prevalence and genotyping of Pseudomonas aeruginosa from food and human sources
Pseudomonas aeruginosa is a common pathogen of a wide range of nosocomial infections in humans, as well as foodborne illnesses. …
Article scientifique
Structural modeling and docking analysis of canonical and novel resistance-associated missense mutations in Sudanese Escherichia coli
Multidrug-resistant Escherichia coli represents a growing public health challenge in low-resource settings, where therapeutic options and routine genomic surveillance remain …
Article scientifique
Seasonal prevalence of extended-spectrum β-lactamase–producing bacteria in food-chain animals, humans, and the surrounding environment in Fayoum governorate: a one health approach
Extended-spectrum β-lactamase (ESBL) producers, particularly Escherichia coli and Klebsiella pneumoniae , pose a growing One Health challenge influenced by seasonal …
Article scientifique
Comparative in vitro cytotoxicity of free curcumin and a liposomal curcumin formulation on various human cancer cell lines
Phospholipids derived from plants are promising for drug delivery applications. This study aimed to develop liposomes from cost-effective, plant-derived soy …
Article scientifique
Transmission dynamics of Klebsiella pneumoniae in a neonatal intensive care unit in Zambia before and after an infection control bundle
Klebsiella pneumoniae is a leading cause of neonatal sepsis in low- and middle-income countries, with antimicrobial resistance (AMR) significantly contributing …
Article scientifique
Heme oxygenase-1 and malaria pathogenesis
Malaria is a life-threatening parasitic disease and remains a major cause of morbidity and mortality worldwide. The clinical course of …
Article scientifique
Essential micronutrients and biguanides (metformin) synergistic and antagonistic interactions on neurocognitive outcomes in type two diabetes mellitus: a systematic review of preclinical and clinical evidence
Background: Type 2 diabetes mellitus (T2DM) represents a systemic disease that extends beyond metabolic dysfunction to include accelerated neurocognitive decline …
Article scientifique
Carbapenemase-producing Enterobacteriaceae and Acinetobacter species among pregnant women in Rivers State, Nigeria
Purpose: To investigate the prevalence, antibiotic resistance profiles, and carbapenemase production among Enterobacteriaceae and Acinetobacter spp. isolated from pregnant women …
Article scientifique
Data Contamination in Neural Hieroglyphic Translation: A Reproducibility Study
Ancient and endangered languages pose a unique challenge for NLP: their datasets are inherently scarce, difficult to expand, and built …
Article scientifique
Prevalence, antibiogram and whole genome sequence of multidrug-resistant Klebsiella pneumoniae isolated from community-onset urinary tract infections in Calabar, Southern Nigeria.
Purpose: To carry out genome characterization of clinical multidrug-resistant Klebsiella pneumoniae strains isolated from urine samples and determine the clones …
Article scientifique
The importance of eels ( Anguilla spp.) for inland small-scale fisheries in local communities of the uMngeni and uThukela catchments, KwaZulu-Natal, South Africa
African freshwater eels (Anguilla spp.) are an overlooked economic resource currently under threat. In South Africa, these populations have been …
Article scientifique
Identification of Alstonia boonei-derived Phytocompounds as Promising Drug Candidates against Plasmodium falciparum Dihydroorotate Dehydrogenase Protein in Malaria Treatment
Purpose: To evaluate phytocompounds from Alstonia boonei as promising anti-malarial drug candidates and determine their interactions with a key Plasmodium …