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Publications
7385 publication(s) trouvée(s)
Article scientifique
Synergistic therapeutic impact of dichloroacetate nanoparticles and doxorubicin in modulating pyruvate dehydrogenase kinase in breast carcinoma model
Abstract Breast cancer is treated with chemotherapies causing severe organ side effects. Increased pyruvate dehydrogenase kinase (PDK) enzymes in cancer …
Article scientifique
A systematic review and meta-analysis of knowledge, attitudes, and practices toward anthrax prevention and control in Ethiopia: Implication for a one health policy
BACKGROUND: Anthrax is one of the tropical diseases that are often overlooked... Anthrax's burden extends beyond its effects on health; …
Article scientifique
Transcriptional regulator NtrC modulates nitrogen assimilation, virulence, and the extracellular glutamine synthetase activity in Acinetobacter baumannii
Acinetobacter baumannii is a growing threat characterized by worrisome antibiotic resistance. A deeper understanding of its resistance and virulence mechanisms …
Article scientifique
Parental knowledge and barriers to cleft lip and palate care: a cross-cultural study from the Middle East and South Asia
Background: Orofacial clefts, including cleft lip and/or palate (CLP), are common congenital anomalies that can cause feeding difficulties, speech articulation …
Article scientifique
Genetic diversity and population structure in Ethiopian Urochloa brizantha genotypes uncovered using inter simple sequence repeat (ISSR) markers
Urochloa brizantha is a tropical C4 grass belonging to the Urochloa genus. Despite its immense potential as animal feed and …
Article scientifique
Long-term preservation of bacteria in washed sterile sand: A 14-year study
BACKGROUND: Cryopreservation and lyophilization are standard methods for preserving microbial cultures, but they are expensive and labor-intensive, creating a barrier …
Article scientifique
Carbapenem resistant Klebsiella pneumoniae isolates at a tertiary hospital in Cape Town, South Africa, are dominated by specific local clones rather than previously described international lineages
Carbapenem-resistant K. pneumoniae (CRKP) are increasingly prevalent pathogens in hospital settings worldwide. In early 2019, an outbreak of carbapenem-resistant Enterobacterales …
Article scientifique
Biophysical techniques for protein secondary structure analysis: a comprehensive review
The determination of protein secondary structure constitutes a fundamental step in understanding protein function, folding mechanisms, and disease pathology. This …
Article scientifique
Unlocking Ethiopia’s genomic landscape and its global significance: a call for inclusive genomics research
Ethiopia, located at the intersection of Africa and Eurasia, is a hub of human genetic diversity and cultural richness. Its …
Article scientifique
Successes, constraints, and prospects for sustainable dairy cattle breeding using artificial insemination technology in Tanzania. A brief review
Dairy farming makes a substantial contribution to both food security and revenue generation, but because artificial insemination (AI) technology is …
Article scientifique
Seasonal dynamics of fish-borne pathogens and water quality in Lake Nasser, Egypt: Environmental correlates and One Health implications
Background and Aim: Seasonal variation profoundly influences aquatic ecosystems, altering water quality, microbial ecology, and food safety. In Egypt’s Lake …
Article scientifique
Modulation of PDX1 gene expression and glycemic control by Citrullus lanatus in experimental type 2 diabetes
Diabetes mellitus is a major global health burden characterized by hyperglycemia, oxidative stress, and progressive pancreatic β-cell dysfunction. Despite the …
Article scientifique
Screening anticancer activity by Brine shrimp lethality test of extracts of Annona stenophylla (Engl. & Diels), Strophanthus petersianus (Klotzsch) and Synadenium glaucescens (Pax)
Cancer continues to be one of the main public health challenges, driving the search for new compounds with therapeutic potential. …
Article scientifique
Dissemination of integrons and carbapenemase-encoding genes among multidrug resistant Proteus mirabilis isolated from urinary tract infections in Egypt
BACKGROUND: Proteus mirabilis (P. mirabilis) is an opportunistic pathogen responsible for various community-acquired and nosocomial infections, particularly urinary tract infections …
Article scientifique
Extended-spectrum β-lactamase and carbapenemase-producing Enterobacterales among adult patients and their family members at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
BACKGROUND: Extended-spectrum β-Lactamase and Carbapenemase-producing Enterobacterales cause severe infections and currently, they are spreading beyond hospitals and becoming a serious …
Article scientifique
Global research trends on bacterial contamination and microbiological quality of ready-to-eat foods: a bibliometric analysis
Background Ready-to-eat (RTE) foods are increasingly consumed worldwide due to urbanization, dietary shifts, and globalization of food systems, yet they …
Article scientifique
AI-powered analysis of viral metagenomic sequencing data for rapid outbreak investigation and novel pathogen discovery
Emerging viral outbreaks continue to pose a persistent global health threat, underscoring the urgent need for a shift from reactive …
Article scientifique
Detection of Antibiotic Resistance Genes in Escherichia coli Isolated From Healthy Livestock in Umuahia
The use of antimicrobials in animal farming is considered the most important factor promoting the emergence, selection, and dissemination of …
Article scientifique
Emerging trends and resistance patterns of extended-spectrum beta-lactamases producing Enterobacteriaceae: an epidemiological insight from Ibn Tofail hospital in Marrakesh, Morocco
INTRODUCTION: The epidemiology of ESBL infection varies widely from one region to another and rapidly evolves across hospital and community …
Article scientifique
Effect of Poly (2-hydroxyethyl methacrylate) on the Release of Phenylacetaldehyde from Chitosan Matrix
Abstract To investigate the effect of Poly (2-hydroxyethyl methacrylate) on the extended release of Phenylacetalde-hyde, considered as a prototype of …