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Publications
7369 publication(s) trouvée(s)
Article scientifique
Azurin a potent anticancer and antimicrobial agent isolated from a novel Pseudomonas aeruginosa strain
Abstract Azurin, a bacterial blue-copper protein, has garnered significant attention as a potential anticancer drug in recent years. Among twenty …
Article scientifique
Monascus red pigment influence on hydroxyapatite nanoparticles-mediated renal toxicity in rats
Hydroxyapatite nanoparticles (HANPs) have been applied in several biomedical fields. However, its interaction with biological systems is less exploited. This …
Article scientifique
Diabetic ketoacidosis treatment outcomes and its associated factors among adult patients with diabetes mellitus admitted to public hospitals in Nekemte Town, Ethiopia: a cross-sectional study
Background: Diabetic ketoacidosis (DKA) is a serious and acute complication of diabetes mellitus. In Ethiopia, the mortality associated with acute …
Article scientifique
Expression of some circulating microRNAs as predictive biomarkers for prognosis and treatment response in glioblastoma
Glioblastoma multiforme (GBM) is the most prevalent, treatment-resistant, and fatal form of brain malignancy. It is characterized by genetic heterogeneity, …
Article scientifique
Genetic diversity and population structure studies of West African sweetpotato [Ipomoea batatas (L.) Lam] collection using DArTseq
BACKGROUND: Sweetpotato is a vegetatively propagated crop cultivated worldwide, predominantly in developing countries, valued for its adaptability, short growth cycle, …
Article scientifique
Effect of a high dose atorvastatin as adjuvant therapy to mesalamine in attenuating inflammation and symptoms in patients with ulcerative colitis: a randomized controlled pilot study
Background Ulcerative colitis (UC) is a chronic inflammatory disorder of the colon. Several preclinical studies investigated the beneficial effects of …
Article scientifique
Optimization and characterization studies of poultry waste valorization for peptone production using a newly Egyptian Bacillus subtilis strain
Valorization of poultry waste is a significant challenge addressed in this study, which aimed to produce cost-effective and sustainable peptones …
Article scientifique
Antimicrobial activity of Monascus purpureus-derived red pigments against Salmonella typhimurium, Escherichia coli, and Enterococcus faecalis
The rise of antimicrobial-resistant microorganisms (AMR) poses a significant global challenge to human health and economic stability. In response, various …
Article scientifique
Therapeutic potential of Curcuma longa against monkeypox: antioxidant, anti-inflammatory, and computational insights
Background Monkeypox (Mpox) is a re-emerging zoonotic disease with limited therapeutic options, necessitating the exploration of novel antiviral agents. Curcuma …
Article scientifique
Building resilience against cholera: lessons from the implementation of integrated community strategy for cholera control in Zambia
Cholera has remained a persistent public health challenge in Zambia since the country's first reported outbreak in 1977. The recent …
Article scientifique
Evaluation of the phytochemical profile, biological activities, and acute toxicity of Cistus ladanifer aerial part extracts: experimental and in silico investigations
Introduction Using both experimental and in silico approaches, this study aimed to evaluate the phytochemical composition and biological activities of …
Article scientifique
Response surface methodology and repeated-batch fermentation strategies for enhancing lipid production from marine oleaginous Candida parapsilosis Y19 using orange peel waste
Oleaginous yeasts are considered promising sources for lipid production due to their ability to accumulate high levels of lipids under …
Article scientifique
The therapeutic role of naringenin nanoparticles on hepatocellular carcinoma
BACKGROUND: Naringenin, a flavonoid compound found in citrus fruits, possesses valuable anticancer properties. However, its potential application in cancer treatment …
Article scientifique
Effect of cisplatin/gold chitosan nanocomposite on oral squamous cell carcinoma and oral epithelial cells
Abstract Background Oral squamous cell carcinoma (OSCC) treatment represents a great challenge, since platinum-based therapeutic agents have deleterious effects on …
Article scientifique
Unmasking the Neglected Cholera Outbreaks in Sub-Saharan Africa
Cholera is a communicable infection that is predominantly transmitted by the bacterium Vibrio cholerae after ingesting contaminated water or food. …
Article scientifique
Passenger co-deletion confounds glutaminolysis signatures anchored on PTEN loss: a cautionary case for location-aware signature design
PTEN-deficient tumors are widely assumed to be glutamine-dependent, a view that has helped motivate the clinical development of glutaminase inhibitors. …
Article scientifique
Harnessing shrimp shell waste: enhanced chitinase production through optimization techniques for ecofriendly solutions using bacteria
Chitinous wastes, particularly shrimp shell residues, represent a major underutilized biomass resource with significant potential for bioconversion into high-value products. …
Article scientifique
Root colonization dynamics of alginate encapsulated rhizobacteria: implications for Arabidopsis thaliana root growth and durum wheat performance
Bioencapsulation in alginate capsules offers an interesting opportunity for the efficient delivery of microbial inoculants for agricultural purposes. The present …
Article scientifique
Genome-wide association mapping and genomic prediction analyses reveal the genetic architecture of grain yield and agronomic traits under drought and optimum conditions in maize
BACKGROUND: Drought is a major abiotic stress in sub-Saharan Africa, impacting maize growth and development leading to severe yield loss. …
Article scientifique
Genomic Factors Associated with Invasiveness in Klebsiella pneumoniae Isolates from Hospitalised Adults in Johannesburg, South Africa