Pregnancy Rate After Myomectomy and Associated Factors Among Reproductive Age Women Who Had Myomectomy at Saint Paul’s Hospital Millennium Medical College, Addis Ababa: Retrospective Cross-sectional Study.

Abstract Introduction: Uterine myoma occurs in 20-50% of reproductive age women. Uterine myomas may be associated with 5-10% of cases of infertility, but it is the sole cause or factor in only 2-3% of all infertility cases. Myomectomy is surgery done to remove myoma regardless of the methods.Objective: to assess impact of myomectomy on pregnancy rate and associated factors among reproductive age women who had myomectomy at St. Paul’s Hospital Millennium Medical College, in Addis Ababa. Methodology: Hospital based retrospective cross-sectional study was conducted to determine pregnancy rate after myomectomy & its associated factors. Patients who had myomectomy in SPHMMC from September, 2012 to September, 2017 were enrolled. Information was retrieved from hospital records & phone interviews with the patients. The strength of statistical association was measured by adjusted odds ratios and 95% confidence intervals. Statistical significance was declared at p-value < 0.05. Result: Among 180 females participated in this study, 52.2% got pregnant after myomectomy. The result showed that females with age >35 years were 0.31 times less likely to get pregnant after surgery than those ages 20-25 years [AOR=0.31(95%CI: 0.29-0.54)]. People with no infertility before surgery were 1.19 times more likely to be pregnant after surgery than those with unexplained infertility before the surgery [AOR=1.19(95%CI: 1.06-1.57)]. People with two uterine incisions were 0.06 times less likely [AOR=0.06(95%CI: 0.043-0.51)] while those with three or more than three incisions were 0.02 times less likely [AOR=0.02(95%CI: 0.002-0.22)] to get pregnant compared with those with one incision on uterine wallConclusion: Age, number of incision and infertility before surgery were significantly associated with rate of pregnancy after myomectomy.