The diagnosis and management of depression in the era of the DSM-5

Depressive disorders comprise a range of conditions that can be viewed along many dimensions. The Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) introduced several changes to the chapter on depressive disorders largely informed by advances in neuroscience, clinical and public health needs and difficulties identified with the previous DSM-IV classification system and criteria. Clinical characteristics vary across depressive disorders, as do the corresponding treatments. Pharmacotherapy and psychotherapy should be tailored to the individual patient.