Prophylactic and immune modulatory influences of Nigella sativa Linn. in broilers exposed to biological challenge

BACKGROUND AND AIM: Linn. in broilers under biological stress. MATERIALS AND METHODS: day old. A total of 1050 samples (150 serum, 150 swab, and 750 organ samples) were collected and examined. RESULTS: Linn. supplemented group in performance traits (body weight, weight gain, and performance index), biochemical parameters (proteinogram, liver enzymes, and creatinine), immunoglobulins concentration, and immune organs' weight. Meanwile, liver showed improvement of histoarchitecture without fibrosis. Heart showed a mild pericarditis with a mild degree of hydropic degeneration. Bursa, thymus, and spleen showed lymphoid hyperplasia. CONCLUSION: Linn. in broiler's feed can improve the immune response and subsequent resistance of broilers against diseases.