Clinical profile and outcome of children with shock admitted at a tertiary hospital in Addis Ababa

Abstract Background: Shock is an acute syndrome characterized by the body's inability to deliver adequate oxygen to meet the metabolic demands of vital organs and tissues. Early diagnosis and initiation of aggressive management is critical before it reaches irreversible stage and finally death occurs Objective: To determine the prevalence, type, outcome and determinants of outcome of shock in children at Saint Paul hospital Millennium Medical College. Methods: This is a cross-sectional analytical study conducted from January 1, 2020 to June 30, 2020 at Saint Paul hospital Millennium Medical College, a tertiary teaching hospital. All Children above neonatal age with a diagnosis of shock was included in the study. Results: Out of 1605 patients seen in the pediatric department 31 (1.9%) of them were diagnosed with shock. The most common type of shock was hypovolemic shock (64.2%) followed by septic shock (32.3%) and only 1 patient with a diagnosis of cardiogenic shock. Most of the participants were below the age of two years (74.2%). Mortality rate was 25.8%. Highest mortality was seen in septic shock (50%) and in hypovolemic shock (15%). Significant correlation was found between hypoglycemia, need of mechanical ventilation support, multi organ dysfunction and poor outcome with P value of 0.038, 0.04, and 0.00 respectively. Conclusion: Hypovolemic shock was the commonest type of shock. Septic shock carries the highest mortality. Hypoglycemia, need of MV support, and MOD was significantly related with poor outcome