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Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya

Article scientifique 2021 Anglais

Résumé

Observed SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observed nationwide and seroprevalence was 9.1% (95%CI 7.6-10.8%). Seroprevalence in Nairobi was 22.7% (18.0-27.7%). Although most people remained susceptible, SARS-CoV-2 had spread widely in Kenya with apparently low associated mortality.

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Adetifa, I., Uyoga, S., Gitonga, J., Mugo, D., Otiende, M., Nyagwange, J., Karanja, H., Tuju, J., Wanjiku, P., Aman, R., Mwangangi, M., Amoth, P., Kasera, K., Ng’ang’a, W., Rombo, C., Yegon, C., Kithi, K., Odhiambo, E., Rotich, T., Orgut, I., Kihara, S., Bottomley, C., Kagucia, E., Gallagher, K., Etyang, A., Voller, S., Lambe, T., Wright, D., Barasa, E., Tsofa, B., Bejon, P., Ochola‐Oyier, L., Agweyu, A., Scott, J., Warimwe, G. (2021). Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya. https://doi.org/10.1038/s41467-021-24062-3

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