Evaluation of human-specific RNA enrichment kits for transcriptome sequencing in a non-model organism: the African savanna elephant (Loxodonta africana)
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S. Engel, Tracey Jooste, Tanya J. Kerr
A pilot study of antiseptic pleural irrigation with povidone-iodine in adults with pleural infection
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Maged Hassan, Basma Elshaarawy, Asmaa Elshazly
Gold Price Dynamics and Economic Growth in Ghana: Evidence from an ARDL Bounds Testing Approach
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Thomas Osei Bonsu Dankwah, Selva D. Kumar, Samuel Kwarteng
High clonal diversity, resistome, and virulome of Escherichia coli causing sepsis in Ethiopian tertiary hospitals: a multicenter genomic study
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Melese Hailu Legese, Daniel Asrat, Dejenie Shiferaw Teklu
Background WHO-priority multidrug-resistant (MDR) Escherichia coli poses major global health challenges, especially in low- and middle-income countries. Methods From October 2019 to September 2020, a …
Neonatal left lung agenesis presenting as pneumonia in a resource-limited setting: a case report
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Beniam Tadewos Lamboro, Samuel Girma, Nathanael Elias Temesgen
Optimization of recyclable citric acid pretreatment for enhanced bioethanol production from heterogeneous starchy food wastes
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Amr Kamal, Mohamed Gomaa, Nivien A. Nafady
Adherence to medications, lifestyle advice, and self-monitoring for type 2 diabetes and hypertension in sub-Saharan Africa: A systematic review, meta-analysis, and interactive network analysis
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Angeliki Apostolou, Reuben Simfukwe, Adrias Saint
BACKGROUND: Type 2 diabetes and hypertension are major public health challenges in sub-Saharan Africa, yet treatment control remains poor. Patient adherence to key treatment pillars …
Factors associated with the recurrence of cholera outbreaks in Rumonge Health District in Southern Burundi: An unmatched case-control study
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Emile Nkurunziza, Robert Kogi
Cholera remains a public health concern in Rumonge Health District. The area is regularly affected by the disease outbreaks despite control measures that are periodically …
Application of quality by design principles in topical semisolid formulations development: a systematic review of CQA, DoE, and control strategies
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Yesuneh Tefera Mekasha, Melaku Getahun Feleke, Yousuf Mohammed
Abstract Topical semisolid formulations such as creams, ointments, and gels play a critical role in dermatological therapy by delivering drugs locally while minimizing systemic exposure. …
The Cascading Failure Chain: A Scoping Review of Barriers to Disruptive Digital Technology Adoption in South African Disaster Management
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Mosekama Osia Mokhele
Optimized plant-based peanut- and milk-free RUTF meets protein quality standards and demonstrates favourable maternal acceptability
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Oluwaseun F. Akinmoladun, Victoria A. Jideani, Oluwaseun Peter Bamidele
Conventional ready-to-use therapeutic foods (RUTFs) rely on peanut and milk ingredients, contributing to high cost, allergen concerns and import dependency in low-resource settings. This study …
Investigation of lakes sediment and solar-integrated photo-bioreactors effect on the lipid production from Spirulina platensis
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El-Sayed Sehsah, Ayoup M. Ghrair, Nabiha Abuelhana
The main objectives of the current research assess how engineering and environmental factors affect the production of lipids oil from Spirulina (Arthrospira platensis) in solar-integrated …
Impact of hydrological variability on the quality of irrigation water from the Beni Bahdel Dam (western Algeria)
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Hadjila Othman, Baghli-Merabet Naoual, Kazi Tani Hicham Abdeslam
In semi-arid regions, climate fluctuations and recurrent drought episodes strongly affect both the quantity and quality of surface water stored in reservoirs.In this context, the …
The pathway to establishing and implementing opioid agonist therapy (OAT) for people who inject drugs in Nairobi, Kenya
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Emily Koech, Christopher Welsh, Mercy Karanja
Sub-Saharan Africa (SSA) is experiencing a burgeoning population of people who inject heroin. This has created an urgent need for the scale-up of comprehensive harm …
The potential therapeutic effect of quercetin on mitochondrial dysfunction in hepatorenal toxicity induced by aluminum chloride in an experimental rat model
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Tasneem N. Hafez, Magda Abdel-Ghany Megahed, Bothaina F. Mahmoud
Aluminum is a xenobiotic element known to induce hepatorenal toxicity through mechanisms involving mitochondrial dysfunction, oxidative stress, and inflammation. Quercetin, a dietary flavonoid with potent …
Hydro-demographic drivers of aquifer depletion and urban water insecurity in Borama, Somaliland: a mixed-methods assessment
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Ahmed Awale Ahmed, Suleiman Hassan Ali, Abdirizak Mohamed Moumin
Background In semi-arid, data-scarce regions, the convergence of climate change and rapid urbanization poses a severe threat to groundwater-dependent cities. This study evaluates the impact …
Effects of hydrogen cyanamide and garlic extract on dormancy release, yield, and fruit quality of low-chill apple cultivars at Debre Tabor, northwestern Ethiopia
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Dessie Fisseha Bitew, Daniel Ayalew Mengistu, Melkamu Alemayehu
Abstract Incomplete dormancy release due to insufficient winter chilling is a major constraint to apple ( Malus domestica Borkh.) production in tropical highland environments. This …
Acaricidal activity of silver nanoparticles biosynthesized from unripe fruits of Solanum elaeagnifolium Cav. against Tetranychus urticae Koch
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Salwa Mahmoud El-Sayed, Amany M. Ahmed, Heba Emam
Abstract Background Tetranychus urticae Koch, is a globally significant agricultural pest. Its rapid development of resistance to conventional acaricides poses a major challenge to effective …
Artificial intelligence approach for predicting suicide-related behaviour in emergency departments
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Tsholofelo Mokheleli, Tebogo Bokaba, Patrick Ndayizigamiye
Abstract Suicide remains a major public health challenge, with emergency departments (EDs) representing a critical point of contact for individuals at risk. However, conventional suicide …
Artificial intelligence-based photographic detection of pink esthetic score attributes using a hybrid deep learning segmentation pipeline: a method development study
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Mihad Ibrahim, Ghada Gamal Adayil, Nouran Hany
This study aimed to develop and internally validate a novel anatomy-driven artificial intelligence (AI) system for automated postoperative Pink Esthetic Score (PES) evaluation from intraoral …